Combined Immunodeficiency
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Genetic Basis of Immunodeficiency
This update describes an NHLBI-funded study investigating the genetic basis of severe combined immunodeficiency (SCID) that is currently rec…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Immune Disorder HSCT Protocol [Phase 2]
Phase 2 clinical trial update on a hematopoietic stem cell transplant protocol for several inherited immune deficiency disorders; the study …
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Expanded Access to CD34+ Selection Utilizing Miltenyi CliniMACS Prodigy® for Patients Receiving Peripheral Blood Stem Cell Transplantations and Stem Cell Boosts
This clinical trial update describes expanded access to CD34+ selection using the Miltenyi CliniMACS Prodigy for patients receiving peripher…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Autologous Gene Therapy for Artemis-Deficient SCID [Phase 1, Phase 2]
Clinical trial update for autologous Artemis-deficient SCID gene therapy, currently recruiting in Phase 1/Phase 2.
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Study of Populations at Risk of Developing Chronic Hepatitis Linked to Chronic Enteric Virus Infection in Patients With Primary Immunodeficiency and Secondary Humoral Deficiency
This clinical trial update indicates the study is currently recruiting to evaluate populations at risk of developing chronic hepatitis linke…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a haploidentical transplant approach using TCRα/β depletion followed by CD45RA-depleted donor lymphocy…
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Feasibility Study to Assess an Adapted Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Transplantation [NA]
This ClinicalTrials.gov update reports a completed feasibility study evaluating an adapted physical activity program for children, adolescen…
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CLINICAL_TRIALS research · 2014-09-04Clinical Trial Update: Clinical Characteristics and Genetic Profiles of Severe Combined Immunodeficiency in China
An update on a study examining the clinical characteristics and genetic profiles of Severe Combined Immunodeficiency in China.