Septic Shock
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Sign up freeTop drugs studied for this disease
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FDA approval · 2021-01-29FDA Approved: NOREPINEPHRINE BITARTRATE — Original Application (Sun Pharmaceutical Industries, Inc.)
FDA approved norepinephrine bitartrate injection from Sun Pharmaceutical Industries as an original-application generic product.
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CLINICAL_TRIALS trial_result · 2021-01-29Clinical Trial Update: Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial [Phase 2, Phase 3]
Phase 2/Phase 3 trial investigating ascorbic acid, corticosteroids, and thiamine (ACTS) in sepsis and septic shock; study completed with res…
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CLINICAL_TRIALS trial_result · 2021-01-26Clinical Trial Update: Triple Therapy in Septic Shock Patients [Phase 3]
A Phase 3 clinical trial evaluating triple therapy in septic shock/sepsis patients has completed recruitment and status is listed as complet…
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CLINICAL_TRIALS trial_result · 2021-01-06Clinical Trial Update: Release of Nociceptin From Granulocytes in Sepsis
Clinical trial update on releasing nociceptin from granulocytes in sepsis; study completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-10-28Clinical Trial Update: Ascorbic Acid and Thiamine Effect in Septic Shock [Phase 2]
Phase 2 clinical trial on the effect of ascorbic acid and thiamine in septic shock/sepsis has completed.
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis [Phase 3]
Phase 3 trial evaluating a vitamin C, thiamine, cyanocobalamine, pyridoxine, and hydrocortisone regimen in sepsis and septic shock has compl…
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CLINICAL_TRIALS trial_result · 2020-09-02Clinical Trial Update: Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic Shock [Phase 1, Phase 2]
A pharmacokinetic and biomarker study of pioglitazone conducted in adolescents with severe sepsis and septic shock completed Phase 1 and Pha…
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CLINICAL_TRIALS trial_result · 2020-07-30Clinical Trial Update: Evaluation of the Role of Hydrocortisone Either Alone or Combined With Fludrocortisone in the Outcome of Septic Shock in Adults [Phase 4]
Phase 4 clinical trial evaluating hydrocortisone alone or with fludrocortisone for outcomes in adults with septic shock; study completed.
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CLINICAL_TRIALS trial_result · 2020-07-09Clinical Trial Update: A Study of IL-7 to Restore Absolute Lymphocyte Counts in Sepsis Patients [Phase 2]
Phase 2 trial evaluating IL-7 to restore absolute lymphocyte counts in patients with severe sepsis and septic shock; study completed with re…
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CLINICAL_TRIALS trial_result · 2020-06-18Clinical Trial Update: Effect of Emergency Department Care Reorganization on Door-to-antibiotic Times for Sepsis (LDS SWARM)
A completed trial assessing how emergency department care reorganization affected door-to-antibiotic times in sepsis and septic shock.
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CLINICAL_TRIALS trial_result · 2020-04-28Clinical Trial Update: Low-chlorine Vs High-chlorine Crystalloids in Septic Shock Adults [Phase 4]
Phase 4 trial update comparing low-chlorine versus high-chlorine crystalloids in adults with septic shock; status not specified.
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CLINICAL_TRIALS trial_result · 2020-03-05Clinical Trial Update: Methylene Blue and Microcirculation in Septic Shock [Phase 3]
Phase 3 clinical trial investigating methylene blue for microcirculation in septic shock; status and results are not provided.
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CLINICAL_TRIALS trial_result · 2020-02-11Clinical Trial Update: Effect of Hydrocortison on Post-ischemic Flow-mediated Dilation and on Thenar Oxygen Saturation in Human Septic Shock. [Phase 2, Phase 3]
A clinical trial evaluating hydrocortisone's effect on flow-mediated dilation and thenar oxygen saturation in adult septic shock patients; t…
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: Effect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic Shock [Phase 3]
Phase 3 trial evaluating IV vitamin C, thiamine, and steroids on mortality in septic shock; study terminated.
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CLINICAL_TRIALS trial_result · 2020-01-28Clinical Trial Update: Ketamine Versus Fentanyl for Induction of Anesthesia in Septic Shock [Phase 4]
A Phase 4 trial comparing ketamine and fentanyl for induction of anesthesia in septic shock has been completed.
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CLINICAL_TRIALS trial_result · 2020-01-09Clinical Trial Update: Impact of Midodrine Administration on the Clinical Outcome of Septic Shock Patients [Phase 4]
Phase 4 clinical trial evaluating the impact of midodrine on outcomes in septic shock patients has completed.
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CLINICAL_TRIALS trial_result · 2019-11-26Clinical Trial Update: Lidocaine-Ketamine Versus Ketamine for Induction of Anesthesia in Septic Shock Patients [Phase 3]
A Phase 3 trial comparing lidocaine-ketamine to ketamine for induction of anesthesia in septic shock patients has completed.
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CLINICAL_TRIALS trial_result · 2019-10-22Clinical Trial Update: Steroids, Thiamine and Ascorbic Acid in Septic Shock [Phase 3]
Phase 3 clinical trial update investigating steroids, thiamine, and ascorbic acid in septic shock.
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CLINICAL_TRIALS trial_result · 2019-10-10Clinical Trial Update: The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial [Phase 2]
Phase 2 trial update for a vitamin C, hydrocortisone, and thiamine regimen in septic shock patients; study completed.
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CLINICAL_TRIALS trial_result · 2019-08-05Clinical Trial Update: Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis: A Pilot Feasibility Study [Phase 1]
A Phase 1 pilot feasibility trial comparing balanced versus normal saline fluids for pediatric sepsis conducted, completed with results post…
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CLINICAL_TRIALS trial_result · 2019-06-04Clinical Trial Update: Rapid Administration of Carnitine in sEpsis [Phase 2]
Phase 2 trial assessing rapid administration of carnitine in septic shock has completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-04-02Clinical Trial Update: Use of Amiodarone in Atrial Fibrillation Associated With Severe Sepsis or Septic Shock [Phase 4]
Phase 4 trial update on using amiodarone for atrial fibrillation in patients with severe sepsis or septic shock; the study is terminated wit…
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CLINICAL_TRIALS trial_result · 2019-02-26Clinical Trial Update: Esmolol to Control Adrenergic Storm in Septic Shock- ROLL-IN 2 [Phase 2]
Phase 2 trial investigating esmolol to control adrenergic storm in septic shock.
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic Shock [Phase 4]
A Phase 4 terminated clinical trial evaluating whether the combination of vitamin C, thiamine, and hydrocortisone affects the clinical cours…
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CLINICAL_TRIALS research · 2019-02-11Clinical Trial Update: Blood Lactate Level for Pre-hospital Orientation of Septic Shock
A clinical trial update evaluating whether blood lactate levels can guide pre-hospital assessment and management of septic shock.