Septic Shock
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-02Clinical Trial Results: Serum Biomarkers to Predict Response to Angiotensin II in Septic Shock [Phase 4]
Phase 4 trial evaluating serum biomarkers to predict response to Angiotensin II in septic shock; results completed and posted.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Role of Echocardiography and Ultrasound Indices in Resuscitation of Septic Shock Patients
A clinical trial update describing a study evaluating the role of echocardiography and ultrasound indices in guiding fluid resuscitation for…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Early Norepinephrine Administration and Rapid Dose Adjustment [NA]
Ongoing clinical trial at Siriraj Hospital evaluating early norepinephrine administration and rapid dose adjustment in sepsis and septic sho…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Effect of oXiris Hemofilter Use in Septic Shock: A Multicenter Retrospective Cohort Study
An ongoing multicenter retrospective cohort study evaluating the use of the oXiris hemofilter in septic shock and multiorgan dysfunction, cu…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Comparative Efficacy and Safety of Propofol-Ketamine Combination Versus Propofol Monotherapy in Geriatric Patients Under Invasive Ventilation [Phase 3]
Phase 3 clinical trial comparing propofol-ketamine combination versus propofol alone in geriatric patients on invasive ventilation; currentl…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Paramedic Initiated Treatment of Sepsis Targeting Out-of-hospital Patients (PITSTOP) [Phase 4]
Phase 4 clinical trial evaluating paramedic-initiated treatment for severe sepsis or septic shock in out-of-hospital patients has completed.
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Clinical Efficacy of Megadose Vitamin C in Sepsis [Phase 2]
A Phase 2 trial evaluating the clinical efficacy of megadose vitamin C in patients with sepsis and septic shock has completed.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: In Vivo Antibiotics Removal During Hemoadsorption Cartridges and Continuous Renal Replacement Therapy in the Intensive Care Unit
Clinical trial update describing a recruiting study that investigates removal of antibiotics during hemoadsorption and continuous renal repl…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock [NA]
This clinical trial evaluates the venous-arterial CO2 gap (CO2gap) as a potential guide for early resuscitation in septic shock and is curre…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Blood Purification for the Treatment of Pathogen Associated Shock [NA]
A clinical trial evaluating blood purification for septic shock sponsored by ExThera Medical Corporation is currently active but not recruit…
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CLINICAL_TRIALS other · 2026-04-14Clinical Trial Update: Study SOLACE SEPSIS [Phase 2]
Phase 2 SOLACE SEPSIS trial is currently recruiting to study septic shock and intracranial hypertension.
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Personalized Mean Arterial Pressure Management on Renal Function During Septic Shock [NA]
This clinical trial update indicates termination of the study NCT01473498 evaluating personalized mean arterial pressure management to prote…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Peripheral Perfusion Index-guided Fluid Resuscitation for Preventing Acute Skin Failure in Elderly Critically Ill Patients [NA]
This clinical trial is recruiting to evaluate whether guiding fluid resuscitation by peripheral perfusion index can prevent acute skin failu…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Dynamic SvO2 in Predicting Fluid Responsiveness in Septic Shock
This clinical trial investigating Dynamic SvO2 to predict fluid responsiveness in septic shock is currently not recruiting, sponsored by Men…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study [NA]
This document provides an update on a randomized, open-label trial evaluating Polymyxin B hemoperfusion for endotoxemic septic shock; the st…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis [NA]
The University of Oklahoma is conducting a clinical trial to study neuromodulation to regulate inflammation and autonomic imbalance in septi…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Protocolized Reduction of Non-resuscitation Fluids Versus Usual Care in Septic Shock Patients [NA]
This clinical trial update describes a protocol evaluating protocolized reduction of non-resuscitation fluids versus usual care in septic sh…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Mechanistic Assessment of Norepinephrine Therapy vs. Angiotensin-II in Septic Shock [Phase 4]
Phase 4 mechanistic trial comparing norepinephrine versus angiotensin II in septic shock; the study is currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Multimodal Vasopressor Strategy in Septic Shock [Phase 2, Phase 3]
The document reports that a Phase 2/Phase 3 trial evaluating a multimodal vasopressor strategy for septic shock has completed.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: The PvCO2-PaCO2/CaO2-CvO2 Ratio in Septic Shock
This clinical trial investigates the PvCO2-PaCO2/CaO2-CvO2 ratio in septic shock and is currently recruiting participants.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Assessing the Efficacy of Dapagliflozin as a Vasculoprotective Treatment in Septic Shock Patients With Microcirculatory Dysfunction [Phase 3]
Phase 3 clinical trial evaluating dapagliflozin as a vasculoprotective treatment for septic shock with microcirculatory dysfunction; sponsor…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Time to Lose the Weight? Comparison of Weight-based and Non-weight-based Vasopressors for Septic Shock
A completed clinical trial comparing weight-based dosing to non-weight-based dosing of vasopressors in patients with septic shock.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Early Methylene Blue in the Microhemodynamics of Septic Patients [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating methylene blue for septic shock and hypoperfusion is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Validation of the Use of the Arteriovenous Tension Difference in CO2 Under Hyperbaric Conditions
An update on a clinical trial validating arteriovenous tension difference in CO2 under hyperbaric conditions. The study is not yet recruitin…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Ivabradine for Heart Rate Control In Septic Shock [Phase 3]
Phase 3 clinical trial evaluating ivabradine for heart rate control in septic shock is currently active but not recruiting.