Septic Shock
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-03-16Clinical Trial Update: Effect of Mesenchymal Stromal Cells on Sepsis and Septic Shock [Phase 1, Phase 2]
Clinical trial update on mesenchymal stromal cells for sepsis and septic shock across Phase 1 and Phase 2 has completed.
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CLINICAL_TRIALS trial_result · 2021-12-10Clinical Trial Update: Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock [Phase 2, Phase 3]
A clinical trial evaluating hydrocortisone, vitamin C, and thiamine for septic shock was terminated after phases 2 and 3.
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CLINICAL_TRIALS trial_result · 2021-10-13Clinical Trial Update: An Open Randomized Study of Dalargin Efectiveness in Combination With Leitragin Drug in Patients With Severe and Critical Manifestations of SARS-COVID-19 [Phase 3]
Phase 3 randomized trial evaluating the combination of Dalargin with Leitragin for severe and critical SARS-CoV-2 infections has completed.
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CLINICAL_TRIALS trial_result · 2021-09-29Clinical Trial Update: Anisodamine Critically Ill SeptIc Shock [Phase 1, Phase 2]
Phase 1/2 trial update for anisodamine in critically ill patients with septic shock; study completed.
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CLINICAL_TRIALS trial_result · 2021-09-24Clinical Trial Update: Terlipressin for Refractory Septic Shock [Phase 2]
Phase 2 trial update for terlipressin in refractory septic shock, currently with unknown status.
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CLINICAL_TRIALS trial_result · 2021-09-23Clinical Trial Update: Unsupervised Machine Learning for Clustering of Septic Patients to Determine Optimal Treatment [Phase 2]
Phase 2 trial exploring unsupervised machine learning to cluster septic patients to determine optimal treatment.
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CLINICAL_TRIALS trial_result · 2021-09-23Clinical Trial Update: Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock [Phase 3]
Phase 3 trial update on vitamin C, thiamine, and hydrocortisone for septic shock has completed.
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CLINICAL_TRIALS trial_result · 2021-09-21Clinical Trial Update: Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis. [Phase 2]
Phase 2 trial updating metabolic resuscitation with ascorbic acid, thiamine, and glucocorticoids in sepsis/septic shock has completed with r…
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CLINICAL_TRIALS trial_result · 2021-09-08Clinical Trial Update: Short-course Antimicrobial Therapy in Sepsis [Phase 2]
Phase 2 trial evaluating a short-course antimicrobial therapy for sepsis.
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CLINICAL_TRIALS trial_result · 2021-09-08Clinical Trial Update: Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa [Phase 2]
Phase 2 clinical trial evaluating safety and dosing of a vitamin C bundle for sepsis treatment in Africa; status and results not publicly pr…
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CLINICAL_TRIALS trial_result · 2021-09-05Clinical Trial Update: COMPACT 2 - COMbining Plasma-filtration and Adsorption Clinical Trial 2 [NA]
A clinical trial update for COMPACT 2 evaluating plasma-filtration and adsorption in septic shock; the study is terminated with results post…
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CLINICAL_TRIALS trial_result · 2021-08-30Clinical Trial Update: The Randomized Controlled Trial of Inferior Vena Cava Ultrasound-guided Fluid Management in Septic Shock Resuscitation [NA]
Completed randomized trial investigating inferior vena cava ultrasound-guided fluid management in septic shock resuscitation; results posted…
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CLINICAL_TRIALS trial_result · 2021-08-10Clinical Trial Update: Clinical Trial of Antioxidant Therapy in Patients With Septic Shock [Phase 3]
Phase 3 trial update of an antioxidant therapy in patients with septic shock and oxidative stress; status currently UNKNOWN.
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CLINICAL_TRIALS trial_result · 2021-07-14Clinical Trial Update: Vitamin C and Septic Shock [Phase 2, Phase 3]
Phase 2/3 trial update on vitamin C for septic shock and sepsis; the study has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-06-28Clinical Trial Update: Esmolol to Treat the Hemodynamic Effects of Septic Shock [Phase 2]
Phase 2 trial investigating esmolol to treat hemodynamic effects of septic shock was terminated with posted results.
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CLINICAL_TRIALS trial_result · 2021-05-20Clinical Trial Update: HCT+F vs. HCT Alone in Critically Ill Medical Septic Shock Patients [Phase 2]
Phase 2 clinical trial comparing HCT+F to HCT alone in critically ill septic shock patients has completed recruitment with results posted.
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CLINICAL_TRIALS trial_result · 2021-05-06Clinical Trial Update: Efficacy and Safety of Therapy With IgM-enriched Immunoglobulin With a Personalized Dose vs Standard Dose in Patients With Septic Shock. [Phase 3]
Phase 3 trial evaluating IgM-enriched immunoglobulin with personalized dosing versus standard dosing in septic shock; efficacy and safety ou…
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CLINICAL_TRIALS trial_result · 2021-04-08Clinical Trial Update: Early Metabolic Resuscitation for Septic Shock [Phase 2]
Phase 2 trial evaluating early metabolic resuscitation for septic shock was terminated, with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-04-06Clinical Trial Update: Selepressin Evaluation Programme for Sepsis-Induced Shock - Adaptive Clinical Trial [Phase 2, Phase 3]
Adaptive trial evaluating selepressin for sepsis-induced shock was terminated; results posted in 2021.
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FDA approval · 2021-03-26FDA Approved: VASOSTRICT — Supplemental Application (Par Health USA, LLC)
The FDA approved a supplemental application for VASOSTRICT (vasopressin) by Par Health USA, LLC.
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CLINICAL_TRIALS trial_result · 2021-03-24Clinical Trial Update: Treatment of Patients With Early Septic Shock and Bio-Adrenomedullin(ADM) Concentration > 70 pg/ml With ADRECIZUMAB [Phase 2]
Phase 2 trial assessing adrecizumab in early septic shock patients with high bio-ADM concentration; completed with posted results.
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FDA approval · 2021-03-15FDA Approved: VASOSTRICT — Supplemental Application (Par Health USA, LLC)
FDA approved a supplemental application for Vasostrict (vasopressin) submitted by Par Health USA, LLC.
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CLINICAL_TRIALS trial_result · 2021-03-09Clinical Trial Update: The Effect of Fluid Resuscitation With 0.9% Sodium Chloride Versus Balanced Crystalloid Solution on Renal Function of Sepsis Patients [Phase 3]
Phase 3 trial comparing 0.9% sodium chloride to balanced crystalloids for renal function in sepsis patients has completed.
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CLINICAL_TRIALS trial_result · 2021-03-03Clinical Trial Update: The Effect of Remote Ischemic Conditioning on the Microcirculation in Sepsis [Phase 1, Phase 2]
Clinical trial update on remote ischemic conditioning for microcirculation in septic patients (Phase 1/Phase 2) completed.
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CLINICAL_TRIALS trial_result · 2021-02-10Clinical Trial Update: Therapeutic Plasmaexchange in Early Septic Shock [Phase 2]
Phase 2 trial update on therapeutic plasmaexchange for septic shock has completed.