Septic Shock
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Near Infrared Spectroscopy (St02)
This entry notes the completed clinical trial using near-infrared spectroscopy (St02) in septic shock conducted by Beth Israel Deaconess Med…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Effects of Electrical Stimulation for Preventing Loss of Muscle Mass in Patients With SIRS, Sepsis and Septic Shock [NA]
A completed clinical trial evaluating whether electrical stimulation can prevent loss of muscle mass in patients with systemic inflammatory …
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Observational Study to Evaluate Peripheral IntraVenous Analysis (PIVA) in Euvolemic, Hypovolemic, and Hypervolemic Emergency Department Patients
The observational trial evaluating Peripheral IntraVenous Analysis (PIVA) in euvolemic, hypovolemic, and hypervolemic emergency department p…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: Albumin Replacement Therapy in Septic Shock [Phase 3]
Phase 3 trial evaluating albumin replacement therapy for septic shock was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-10-26Clinical Trial Update: Microcirculation Properties of Albumin for Fluid Resuscitation in Septic Shock [NA]
A completed clinical trial evaluating the microcirculation effects of albumin for fluid resuscitation in patients with septic shock.
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Study of Subcutaneous Interstitial Pressure During Sepsis [NA]
Clinical trial update indicating completion of a study examining subcutaneous interstitial pressure in patients with septic shock.
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Quantitative Ultrasound Assessment of Abdominal Cavity Space
Clinical trial update describing a quantitative ultrasound study to assess the abdominal cavity space in patients with sepsis and multi-orga…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of 3 Doses of MOTREM (Nangibotide) in Patients With Septic Shock [Phase 2]
Phase 2 study evaluating safety, tolerability, pharmacokinetics and pharmacodynamics of three doses of MOTREM (nangibotide) in patients with…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Lipopolysaccharide Adsorption At Septic Shock [NA]
A completed trial evaluating lipopolysaccharide adsorption for septic shock.
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: Renin and Renal Biomarker Response to Angiotensin II [Phase 4]
This Phase 4 trial update reports results evaluating renin and renal biomarker responses to Angiotensin II in patients with septic shock and…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Diastolic Dysfunction in Septic Shock and Cardiomyopathy Genetic Variants
A completed clinical trial update examining diastolic dysfunction in septic shock and genetic variants associated with cardiomyopathy.
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Gender-based Differences in the Outcome of the Treatment of Persistent Septic Shock With Hydrocortisone
A completed clinical trial from Alexandria University evaluates whether gender influences outcomes when treating persistent septic shock wit…
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CLINICAL_TRIALS trial_result · 2024-07-22Clinical Trial Update: Impact of Early Sepsis Care Guided by the National Early Warning Score 2 in the Emergency Department [NA]
Completed study evaluating early sepsis care guided by the National Early Warning Score 2 in the emergency department.
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CLINICAL_TRIALS trial_result · 2024-07-10Clinical Trial Update: Adjuvant Use of Neostigmine in Sepsis and Septic Shock. [Phase 2]
A Phase 2 trial led by Mansoura University evaluating adjuvant neostigmine for sepsis and septic shock has completed.
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: Low Dose Versus High Dose Methylene Blue in Septic Patients [Phase 2, Phase 3]
This document reports the completion of a Phase 2/3 trial comparing low-dose versus high-dose methylene blue in patients with septic shock.
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: ILOPROST in Septic Shock With Persistent Microperfusion Defects (I-MICRO) [Phase 3]
Phase 3 trial of iloprost for septic shock with persistent microperfusion defects has completed.
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: TRANSfusion in Patients With Onco-hematological Malignancies ResusciTated From Septic Shock [Phase 3]
A Phase 3 clinical trial evaluating transfusion in patients with hematologic malignancies resuscitated from septic shock has completed.
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Role and Mechanisms of Lipid and Lipoprotein Dysregulation in Sepsis
A completed clinical trial investigating the role and mechanisms of lipid and lipoprotein dysregulation in sepsis and septic shock.
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CLINICAL_TRIALS trial_result · 2024-06-20Clinical Trial Update: The Effect of Early Norepinephrine on Stroke Volume Index, Cardiac Index, Lactate, and Arterial Elastance in Pediatric Septic Shock [Phase 2, Phase 3]
This trial update notes the completion of Phase 2/Phase 3 studies evaluating early norepinephrine in pediatric septic shock, with measuremen…
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CLINICAL_TRIALS trial_result · 2024-06-07Clinical Trial Update: Effects of Fluid Therapy on Peripheral TIssse Perfusion During Sepsis/Septic Shock
This entry notes the completion of a clinical trial evaluating the effect of fluid therapy on peripheral tissue perfusion in septic shock or…
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CLINICAL_TRIALS trial_result · 2024-06-05Clinical Trial Update: Combined Hemoperfusion and Therapeutic Plasma Exchange for Treatment of Patients With Septic Shock
A clinical trial evaluating the combination of hemoperfusion and therapeutic plasma exchange for septic shock has completed.
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Effect of Norepinephrine Administration on Ventricular Systolic Function in Septic Shock
A completed clinical trial evaluating the effect of norepinephrine administration on ventricular systolic function in patients with septic s…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Can Shock Indices Be Prognostic Indicators in Sepsis/Septic Shock?
A completed clinical study evaluated whether shock indices can serve as prognostic indicators in patients with sepsis and septic shock.
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Infusion of Prostacyclin (Iloprost) vs Placebo for 72-hours in Patients With Septic Shock Suffering From Organ Failure [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating 72-hour infusion of iloprost versus placebo in septic shock with organ failure has completed.
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CLINICAL_TRIALS trial_result · 2024-04-26Clinical Trial Update: Pro-inflammatory Role of Blood Platelets in Critically Ill Patients With Septic Shock.
This completed clinical trial investigated the pro-inflammatory role of blood platelets in critically ill patients with septic shock.