Septic Shock
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CLINICAL_TRIALS trial_result · 2026-07-02Clinical Trial Results: Serum Biomarkers to Predict Response to Angiotensin II in Septic Shock [Phase 4]
Phase 4 trial evaluating serum biomarkers to predict response to Angiotensin II in septic shock; results completed and posted.
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Paramedic Initiated Treatment of Sepsis Targeting Out-of-hospital Patients (PITSTOP) [Phase 4]
Phase 4 clinical trial evaluating paramedic-initiated treatment for severe sepsis or septic shock in out-of-hospital patients has completed.
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Clinical Efficacy of Megadose Vitamin C in Sepsis [Phase 2]
A Phase 2 trial evaluating the clinical efficacy of megadose vitamin C in patients with sepsis and septic shock has completed.
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Personalized Mean Arterial Pressure Management on Renal Function During Septic Shock [NA]
This clinical trial update indicates termination of the study NCT01473498 evaluating personalized mean arterial pressure management to prote…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study [NA]
This document provides an update on a randomized, open-label trial evaluating Polymyxin B hemoperfusion for endotoxemic septic shock; the st…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Multimodal Vasopressor Strategy in Septic Shock [Phase 2, Phase 3]
The document reports that a Phase 2/Phase 3 trial evaluating a multimodal vasopressor strategy for septic shock has completed.
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Time to Lose the Weight? Comparison of Weight-based and Non-weight-based Vasopressors for Septic Shock
A completed clinical trial comparing weight-based dosing to non-weight-based dosing of vasopressors in patients with septic shock.
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Ivabradine for Heart Rate Control In Septic Shock [Phase 3]
Phase 3 clinical trial evaluating ivabradine for heart rate control in septic shock is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Adjunctive Methylene Blue in Septic Shock [Phase 3]
Phase 3 trial evaluating adjunctive methylene blue for septic shock has completed with status listed as COMPLETED.
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Prognostic Assessment of Diastolic and Systolic Left Ventricular Function in Septic Shock
This completed clinical trial assesses the prognostic value of diastolic and systolic left ventricular function in septic shock using echoca…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Study Assessing Efficacy of Plasmatherapy in Septic Shock-induced Coagulopathy: Feasibility Study [NA]
This clinical trial update reports a completed feasibility study evaluating plasmatherapy for septic shock–induced coagulopathy.
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Relation Between Mean Arterial Pressure and Renal Resistive Index in the Early Phase of Septic Shock [NA]
This clinical trial update examines the relationship between mean arterial pressure and the renal resistive index in the early phase of sept…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: A Study Looking at the Use of Biomarkers to Provide Early Indication of Acute Kidney Injury in Patients With Sepsis (Limiting AKI Progression In Sepsis) [NA]
BioMérieux's biomarker study to provide early indication of acute kidney injury in sepsis patients has been terminated. The study did not pr…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis [Phase 3]
A Phase 3 pediatric trial comparing balanced crystalloids versus normal saline for sepsis has completed.
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Fluids in Septic Shock (FISSH) [Phase 2, Phase 3]
The Fluids in Septic Shock (FISSH) trial, spanning Phase 2 and Phase 3, has completed its studies. It investigates fluid therapy options for…
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: Antibiotic De-escalation in Onco-hematology Patients for Sepsis or Septic Shock [Phase 3]
Phase 3 trial assessing de-escalation of antibiotic therapy in cancer patients with sepsis or septic shock has completed.
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Early and Late Neutrophil CD64 and Monocyte HLA-DR as Biomarkers for Septic Shock
The clinical trial evaluating early and late neutrophil CD64 and monocyte HLA-DR as biomarkers for septic shock has completed.
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Comparison of Extubation Delay After Prolonged Sedation [Phase 4]
Phase 4 clinical trial update indicating the study on extubation delay after prolonged sedation in septic shock has been terminated.
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Strong Albumin Solutions in Patients With Septic Shock [Phase 2, Phase 3]
This clinical trial update reports on Phase 2 and Phase 3 studies evaluating strong albumin solutions in patients with sepsis and septic sho…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: I.D.E.A.L.-I.C.U. (Initiation of Dialysis EArly Versus deLayed in Intensive Care Unit) [Phase 3]
The Phase 3 IDEAL-I.C.U. trial evaluating early versus delayed dialysis initiation in septic shock patients with acute kidney injury was ter…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: COrporeal Compression at the ONset of Severe Sepsis and Septic Shock [NA]
This clinical trial evaluating corporal compression at the onset of severe sepsis and septic shock has completed.
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Fluid Challenge in Intensive Care The FENICE II Study
The FENICE II study, sponsored by Humanitas Clinical and Research Center, evaluated fluid challenge practices in critically ill patients in …
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Expression of Protein Tyrosine Phosphatase 1B (PTP1B) and Body Composition Modification in Patients With Septic Shock [NA]
Completed clinical trial evaluating expression of PTP1B and its relation to body composition in patients with septic shock.
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Correlation of VEGF-A and Fluid Balance in Septic Shock [NA]
This clinical trial update reports the completion of a study examining the correlation between VEGF-A and fluid balance in septic shock.
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Serum Biomarkers to Predict Response to Angiotensin II in Septic Shock [Phase 4]
A Phase 4 clinical trial update reports on serum biomarkers to predict response to Angiotensin II in septic shock, and notes the trial statu…