Septic Shock
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-04-03Clinical Trial Update: The Effect of Restrictive Fluid Management on Cardiac Function and Glycocalyx Degradation [Phase 4]
Phase 4 clinical trial evaluating the effects of restrictive fluid management on cardiac function and glycocalyx degradation in septic shock…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Impact of Prior SGLT2 Inhibitors Use on the Development and Progression of Sepsis-Associated Acute Kidney Injury
This clinical trial update investigates whether prior use of SGLT2 inhibitors affects the development and progression of sepsis-associated a…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Procalcitonin and Antimicrobial Utilization in Critically Ill Cancer Patients with Sepsis [NA]
ClinicalTrials.gov update on a terminated study evaluating procalcitonin-guided antimicrobial use in critically ill cancer patients with sep…
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: Hypotension in the Weaning From Vasopressor Drugs [Phase 4]
Phase 4 clinical trial evaluating hypotension during weaning from vasopressor therapy in septic shock has completed.
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Evaluation of Hemodynamic Effects of Cascade Hemofiltration in Septic Shock [NA]
Completed clinical trial evaluating the hemodynamic effects of cascade hemofiltration in septic shock.
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Efficacy of Add-on Plasma Exchange As an Adjunctive Strategy Against Septic Shock [NA]
This clinical trial update reports on evaluating add-on plasma exchange as an adjunctive therapy for septic shock; the study is currently re…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: High Cut-Off Continuous Veno-venous Hemodialysis (CVVHD) in Patients Treated for Acute Renal Failure After Systemic Inflammatory Response Syndrome (SIRS)/Septic Shock [NA]
A terminated clinical trial evaluating high cut-off CVVHD in patients with acute kidney failure after systemic inflammatory response syndrom…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: ALBumin Italian Outcome Septic Shock-BALANCED Trial (ALBIOSS-BALANCED) [Phase 3]
This update notes that the ALBIOSS-BALANCED Phase 3 trial evaluating albumin therapy for septic shock has completed.
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CLINICAL_TRIALS trial_result · 2025-03-03Clinical Trial Update: Midodrine Effect on the Mortality Rates in Septic Shock Patients [Phase 2]
Phase 2 trial evaluating midodrine's effect on mortality in septic shock has completed.
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CLINICAL_TRIALS trial_result · 2025-03-03Clinical Trial Update: PCT Guided Stopping of Antibiotic Therapy in Children With Sepsis [NA]
A pediatric sepsis trial evaluated stopping antibiotic therapy early using procalcitonin guidance; the study has completed.
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: The Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care Trial [Phase 4]
A Phase 4 trial comparing conservative versus liberal fluid therapy in septic shock has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Use of Neurostimulation As a Tool for Reconditioning the Neuromuscular System of Patients Admitted to the ICU for Septic Shock [NA]
The clinical trial evaluating neurostimulation to recondition the neuromuscular system in ICU patients with septic shock has been terminated…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Intravenously Administered M6229 in Critically Ill Sepsis Patients [Phase 1]
Phase 1 trial of intravenously administered M6229 in patients with sepsis and septic shock has completed.
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Intravenous Metoprolol in Septic Shock [Phase 2]
A Phase 2 trial evaluating intravenous metoprolol in septic shock has completed, including patients with ventilator-associated pneumonia.
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: Citrulline and Arginase Activity in Severe Sepsis and Septic Shock
A completed clinical trial investigating citrulline levels and arginase activity in patients with severe sepsis and septic shock.
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: PK/PD of Extended-infusion Meropenem, Piperacillin-tazobactam and Cefepime in the Early Phase of Septic Shock [Phase 3]
Phase 3 trial update reports pharmacokinetic/pharmacodynamic data for extended-infusion meropenem, piperacillin-tazobactam, and cefepime in …
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: Evaluating the Effect of Chronic Antihypertensive Therapy on Vasopressor Dosing in Septic Shock
This clinical trial evaluated whether chronic antihypertensive therapy influences vasopressor dosing requirements in septic shock. The study…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Rotational Thromboelastometry Versus DIC Score in Sepsis
An update on a completed clinical trial comparing rotational thromboelastometry to the DIC score in sepsis and septic shock.
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Vitamin C, Hydrocortisone and Thiamine for Septic Shock [Phase 2]
A Phase 2 trial evaluating the combination of vitamin C, hydrocortisone, and thiamine for septic shock was terminated.
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating high-dose vitamin C, hydrocortisone, and thiamine for septic shock, assessing cerebral autoregul…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Muscle Ultrasound Study in Shock Patients
A completed clinical trial at University Hospital, Geneva evaluating muscle ultrasound in patients with septic shock. The snippet does not r…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Thiamine, Vitamin C and Hydrocortisone in the Treatment of Septic Shock [NA]
A completed clinical trial evaluating the combination of thiamine, vitamin C, and hydrocortisone for septic shock.
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CLINICAL_TRIALS trial_result · 2024-11-27Clinical Trial Update: A Trial of Vitamin B12 in Septic Shock [Phase 2]
The document reports completion of a Phase 2 trial evaluating Vitamin B12 in patients with septic shock.
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Risk Factors Identification of Sepsis and Septic Shock After Major Abdominal Surgery Based on Artificial Intelligence
A completed clinical trial investigated artificial intelligence–based identification of risk factors for sepsis and septic shock after major…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Endothelium in Severe Sepsis
A clinical trial investigating endothelial function in severe sepsis has completed.