Septic Shock
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Predictive Mini-bolus Fluid Responsiveness in Pediatric Septic Shock [NA]
A completed pediatric septic shock trial evaluating predictive mini-bolus fluid responsiveness; the update does not report results.
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Does the Time Between the End of Vascular Filling and Evaluation of Its Effectiveness Modify Fluid Challenge Results in Septic Shock?
This completed clinical trial examined whether the timing of evaluating fluid challenges after vascular filling affects the measured respons…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Prospective Validation of Clini-biological Parameters Including Initial Hemostasis, Which Improve the Prediction of Death at 1 Month Among Patients With Septic Shock
This completed clinical trial prospectively validated clini-biological parameters, including initial hemostasis, to improve prediction of 1-…
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Therapeutic Plasma Exchange in Adult Patients With Severe Sepsis [Phase 1]
A Phase 1 clinical trial evaluating therapeutic plasma exchange in adults with septic shock has completed.
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Midodrine Use in Septic Shock [Phase 3]
A Phase 3 trial evaluating midodrine for septic shock was terminated; results were posted on 2025-09-24.
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Guiding Fluid Resuscitation in Septic Shock: Ultrasound vs. Noninvasive Cardiac Output Monitoring [NA]
A completed clinical trial comparing ultrasound-guided fluid resuscitation to noninvasive cardiac output monitoring in patients with septic …
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Guided Fluid-balance Optimization With Mini-fluid chALlenge During Septic Shock [NA]
This clinical trial update reports the completion of a study evaluating guided fluid-balance optimization using mini-fluid challenges in sep…
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: GM-CSF to Decrease ICU Acquired Infections [Phase 3]
Phase 3 clinical trial evaluating GM-CSF to decrease ICU-acquired infections has completed in patients with septic shock and sepsis.
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: Non-Invasive Cardiac Output Monitor (NICOM) for Goal-directed Fluid Resuscitation for Inpatients With Hypotension and/or Septic Shock [NA]
This is a clinical trial update evaluating the NICOM non-invasive cardiac output monitor for goal-directed fluid resuscitation in inpatients…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: L-carnitine as an Adjunct Treatment for Septic Shock Patients With Acute Kidney Injury [Phase 3]
A Phase 3 trial investigating L-carnitine as an adjunct treatment for septic shock patients with acute kidney injury has been terminated.
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: Optimization of Sepsis Therapy Based on Patient-specific Digital Precision Diagnostics [NA]
A completed clinical trial evaluating optimization of sepsis therapy guided by patient-specific digital precision diagnostics.
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: LIPIDS-P Trial Phase I/II Trial [Phase 1, Phase 2]
The LIPIDS-P trial, a Phase I/II study, has completed and posted results evaluating its safety and preliminary efficacy in sepsis and septic…
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: Multicenter Symphony IL-6 Monitoring Sepsis ICU Study
A multicenter clinical trial evaluating interleukin-6 monitoring in ICU patients with sepsis has completed.
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: Recombinant Human Brain Natriuretic Peptide for the Recovery Stage of Septic Shock [NA]
This clinical trial is evaluating recombinant human brain natriuretic peptide for the recovery phase of septic shock in patients with sepsis…
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: Evaluation of Droplet Digital PCR Rapid Detection Method and Precise Diagnosis and Treatment for Suspected Sepsis [NA]
This clinical trial update reports the completed evaluation of a droplet digital PCR rapid detection method aimed at enabling precise diagno…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Empirical Meropenem Versus Piperacillin/Tazobactam for Adult Patients With Sepsis [Phase 4]
A Phase 4 clinical trial comparing empirical meropenem versus piperacillin/tazobactam in adults with sepsis (including septic shock) is curr…
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: Effect of Simulation Application in Septic Shock Management [NA]
A completed clinical trial evaluated the effect of a simulation application on septic shock management. The sponsor listed is Amasya Univers…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Prognostic Value Serum Concentration of Indoxyl Sulfate During Acute Kidney Injury in Septic Shock Patients. [NA]
Completed clinical trial evaluating whether serum indoxyl sulfate levels have prognostic value in patients with acute kidney injury due to s…
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: Lipopolysaccharide Adsorption (Efferon LPS NEO) in Children With Sepsis [NA]
The pediatric sepsis trial evaluating Efferon LPS NEO for lipopolysaccharide adsorption has completed.
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: Hyperdynamic Left Ventricular Ejection Fraction as a Predictor of Mortality in Intensive Care Unit Patients With Septic Shock
The update discusses findings on hyperdynamic left ventricular ejection fraction as a predictor of mortality among septic shock patients in …
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Medical Device (MD) Derived Pharmacokinetic (PK) Parameters for Vancomycin (MD-PK)
Completed clinical trial evaluating pharmacokinetic parameters of vancomycin derived from a medical device. The study investigates how a dev…
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Effect of Fluid Deresuscitation With Central Venous Pressure Target 0-4 mmHg in Septic Shock Patients [NA]
A clinical trial evaluating fluid deresuscitation with a central venous pressure target of 0-4 mmHg in septic shock patients has completed.
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CLINICAL_TRIALS trial_result · 2025-05-01Clinical Trial Update: Vasopressin Use in Septic Shock From Türkiye
This document reports a completed clinical trial from Türkiye evaluating the use of vasopressin in septic shock.
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: The Effect Of Resuscitation Guided By Two Different Dynamic Parameters On Time To Normalization Of The Capillary Refill Time In Adult Patients With Septic Shock [Phase 3]
Phase 3 trial evaluating resuscitation guided by two dynamic parameters in adults with septic shock has completed; the study assessed time t…
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CLINICAL_TRIALS trial_result · 2025-04-15Clinical Trial Update: PLatelets Acetyl-CoA Carboxylase Phosphorylation State in SEPtic Shock [NA]
This trial update notes the completion of a study on platelet acetyl-CoA carboxylase phosphorylation state in septic shock, sponsored by Cli…