Septic Shock
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CLINICAL_TRIALS trial_result · 2017-06-02Clinical Trial Update: Effects of the V1a Agonist FE 202158 in Patients With Septic Shock [Phase 2]
Phase 2 clinical trial evaluating the V1a agonist FE 202158 in patients with septic shock has completed and results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Thiamine as a Metabolic Resuscitator in Septic Shock [Phase 1, Phase 2]
Phase 1 and Phase 2 trials evaluating thiamine as a metabolic resuscitator in septic shock were completed, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-05-02Clinical Trial Update: Candida Host Defense Response After Septic Shock in the Critically Ill
This ClinicalTrials.gov entry reports the completion of a study evaluating the Candida host defense response in critically ill patients foll…
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Balanced Salt Solution VS. Normal Saline Solution in Septic Shock [Phase 3]
Phase 3 trial comparing Balanced Salt Solution to Normal Saline in septic shock has completed.
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CLINICAL_TRIALS trial_result · 2017-04-25Clinical Trial Update: The Effects of Blood Pressure on Renal Function and Oxygenation in Septic Shock [NA]
A completed clinical trial examining how different blood pressure targets influence renal function and oxygenation in septic shock patients.
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CLINICAL_TRIALS trial_result · 2017-04-24Clinical Trial Update: Co-administration of Iloprost and Eptifibatide in Septic Shock Patients [Phase 2]
This document reports the completion of a Phase 2 clinical trial evaluating co-administration of iloprost and eptifibatide in patients with …
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CLINICAL_TRIALS trial_result · 2017-04-14Clinical Trial Update: IMproved PREdiction of Severe Sepsis in the Emergency Department
Completed clinical trial evaluating improved prediction of severe sepsis in the emergency department, sponsored by Axis Shield Diagnostics L…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Effects of Chronic Antihypertensive Therapy on Clinical Outcomes in Septic Shock
A completed clinical trial evaluating the effects of long-term antihypertensive therapy on clinical outcomes in patients with septic shock, …
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Microcirculation After MAP Increase in Septic Shock Patients With Previous Hypertension [Phase 4]
A Phase 4 clinical trial update evaluating microcirculatory effects after increasing mean arterial pressure in septic shock patients with a …
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CLINICAL_TRIALS trial_result · 2017-03-21Clinical Trial Update: Effects of Nursing Staff on Empiric Antibiotic in Septic Shock
Completed clinical trial evaluating how nursing staffing influences empiric antibiotic use in patients with septic shock.
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CLINICAL_TRIALS trial_result · 2017-02-08Clinical Trial Update: Hemodynamic Effects of Dexmedetomidine in Septic Shock [Phase 3]
Phase 3 clinical trial evaluating the hemodynamic effects of dexmedetomidine in septic shock has completed.
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CLINICAL_TRIALS trial_result · 2017-02-02Clinical Trial Update: Clinical Practice Guidelines and Impact of Audit and Feedback in the Emergency Department [NA]
This completed clinical trial evaluated the impact of implementing clinical practice guidelines and audit-and-feedback in the emergency depa…
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CLINICAL_TRIALS trial_result · 2017-01-26Clinical Trial Update: Protocolized Care for Early Septic Shock [NA]
This clinical trial update reports completion and results posting for a study evaluating protocolized care for early septic shock.
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CLINICAL_TRIALS trial_result · 2017-01-26Clinical Trial Update: The Effect of Three Different Fluids(Albumin 5%, Normal Saline, Hydroxyethyl Starch 130 kD) on Microcirculation in Severe Sepsis/Septic Shock Patients
A completed clinical trial evaluated the effects of three IV fluids—albumin 5%, normal saline, and hydroxyethyl starch 130 kDa—on microcircu…
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CLINICAL_TRIALS trial_result · 2017-01-25Clinical Trial Update: Influence of Age, Sepsis and SLCO1A2 Polymorphisms on Rocuronium Pharmacokinetics [Phase 4]
A Phase 4 trial update investigating how age, sepsis, and SLCO1A2 genetics affect rocuronium pharmacokinetics in septic conditions; the stud…
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CLINICAL_TRIALS trial_result · 2017-01-16Clinical Trial Update: Investigating FE 202158 as Potential Primary Treatment in Patients With Early Septic Shock [Phase 2]
Phase 2 clinical trial evaluating FE 202158 as a primary treatment in patients with early septic shock has completed and results were posted…
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: Pharmacokinetic of Doripenem and Piperacillin/Tazobactam in More Than 120 kg Critically Ill Patients [NA]
A completed clinical trial assessing the pharmacokinetics of doripenem and piperacillin/tazobactam in critically ill patients weighing more …
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CLINICAL_TRIALS trial_result · 2016-11-22Clinical Trial Update: Efficacy and Safety of Monotherapy With Noradrenaline and Terlipressin in Patients of Cirrhosis With Septic Shock Admitted to Intensive Care Unit [NA]
A completed clinical trial evaluating the efficacy and safety of monotherapy with noradrenaline and terlipressin in patients with cirrhosis …
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CLINICAL_TRIALS trial_result · 2016-11-22Clinical Trial Update: The Cooling And Surviving Septic Shock Study (CASS) [Phase 2, Phase 3]
The Cooling And Surviving Septic Shock Study (CASS) Phase 2/3 trial has been terminated.
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CLINICAL_TRIALS trial_result · 2016-10-26Clinical Trial Update: Immune Failure in Critical Therapy (INFECT) Study
The INFECT study, investigating immune failure in critical therapy for sepsis and septic shock, has completed its course per ClinicalTrials.…
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: Hypoxia Inducible Factor 1 Alpha as a Novel Biomarker in Septic Shock
The completed clinical trial evaluated hypoxia-inducible factor 1 alpha as a biomarker in septic shock, assessing its potential utility in s…
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CLINICAL_TRIALS trial_result · 2016-08-31Clinical Trial Update: Modulation of Vasoreactivity in Septic Shock: Impact of Recombinant Protein C [Phase 4]
Phase 4 trial evaluating how recombinant protein C modulates vasoreactivity in septic shock has completed.
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CLINICAL_TRIALS trial_result · 2016-08-18Clinical Trial Update: Pilot Study for the SQUEEZE Trial [Phase 3]
The SQUEEZE Trial's pilot Phase 3 study for septic shock has been completed.
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CLINICAL_TRIALS trial_result · 2016-08-12Clinical Trial Update: Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis [Phase 3]
Phase 3 placebo-controlled trial evaluating sodium selenite with procalcitonin-guided antimicrobial therapy in severe sepsis and septic shoc…
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CLINICAL_TRIALS trial_result · 2016-08-04Clinical Trial Update: Study on the Frequency of de Novo Atrial Fibrillation in Septic Shock in Medical Intensive Care [NA]
A completed clinical trial examining how often patients with septic shock in the medical intensive care unit develop de novo atrial fibrilla…