Septic Shock
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Study on the Construction and Application of Early Warning Model of Sepsis in Critically Ill Patients
An ongoing clinical trial from the Second Affiliated Hospital of Wenzhou Medical University is evaluating an early warning model for sepsis …
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: The Preventive Effect of Shenfu Injection on Myocardial Dysfunction in Sepsis [Phase 4]
Phase 4 clinical trial update evaluating Shenfu Injection for preventing myocardial dysfunction in sepsis, with recruitment ongoing for sept…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: First in Human Trial to Assess the Feasibility and Preliminary Safety of Adjunctive Treatment with the HemoSystem REBOOT in Critically Ill Patients with Sepsis-induced Immunosuppression [NA]
This clinical trial update announces a first-in-human study to assess feasibility and preliminary safety of HemoSystem REBOOT as an adjuncti…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Effects of Intravenous Metabolic Recovery Agent in Elderly Septic Patients on Prognosis and Microcirculation. [NA]
A clinical trial update announcing ongoing recruitment for a study of an Intravenous Metabolic Recovery Agent in elderly septic shock patien…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Evaluation of Early Administration of Levetiracetam in the Prevention and Treatment Encephalopathy in Septic Shock: Randomized, Double-blind, Placebo-controlled Trial [Phase 3]
A Phase 3 randomized, double-blind, placebo-controlled trial evaluating early administration of levetiracetam to prevent and treat encephalo…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Ultrasound-guided Blood Sampling Drawing for Microbiological Analysis in the Critically Ill
The document outlines a clinical trial evaluating ultrasound-guided blood sampling for microbiological analysis in critically ill patients w…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Renin Levels as Prognostic Indicators of Septic Shock Severity and Outcome
A clinical trial is investigating whether renin levels can serve as prognostic indicators for severity and outcomes in septic shock and is c…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: Hemodynamic Measurements of Macrocirculatory and Perfusion Parameters in ICU
This clinical trial is recruiting in the ICU to measure macrocirculatory and perfusion parameters in patients with septic shock. The study i…
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CLINICAL_TRIALS research · 2025-03-03Clinical Trial Update: Ventriculo-arterial Coupling and Myocardial Work in Sepsis and Septic Shock [NA]
A clinical trial investigating ventriculo-arterial coupling and myocardial work in sepsis and septic shock is listed as not yet recruiting.
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Evaluating Dynamic Arterial Elastance in Septic Shock Patients. [NA]
This record notes a clinical trial evaluating dynamic arterial elastance in patients with septic shock. The study is currently not yet recru…
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: Evaluation of Blood Protein O-GlcNAcylation Levels in Children
ClinicalTrials.gov shows a pediatric study evaluating blood protein O-GlcNAcylation levels in children with sepsis and septic shock that is …
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: Study on the Improvement of Microcirculation in Patients With Sepsis by Vitamin B6, Vitamin B12 and Vitamin C [NA]
A clinical trial evaluating whether vitamin B6, vitamin B12, and vitamin C can improve microcirculation in patients with septic shock; the s…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Types of Photoplethysmographic Waves in Adult Patients with Septic Shock
A clinical trial evaluating different photoplethysmographic waveforms in adult patients with septic shock; currently recruiting.
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Beta-Lactam Antibiotics InitiaL ExpoSure OptimisEd in CriticallY Ill Patients with SEpsis [Phase 4]
Phase 4 clinical trial assessing optimized exposure of beta-lactam antibiotics in critically ill patients with sepsis, currently recruiting.
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: Pentaglobin in CRE and PA Neutropenic Infections [Phase 2]
Phase 2 clinical trial update for Pentaglobin in neutropenic infections due to CRE and Pseudomonas aeruginosa in septic shock; the study is …
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: Effects of Paroxetine on Cardiovascular Function in Septic Patients [Phase 2]
A Phase 2 clinical trial is investigating the effects of paroxetine on cardiovascular function in patients with septic shock or sepsis, and …
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: Doppler Echocardiography Versus Clinical Targets Guided Therapy on the Outcome of Postpartum Septic Shock. [NA]
This clinical trial compares Doppler echocardiography-guided therapy to clinically guided therapy for outcomes in postpartum septic shock, a…
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CLINICAL_TRIALS research · 2025-01-03Clinical Trial Update: Restricted or Liberal Fluid for Haemodynamic Resuscitation in Sepsis
A registered clinical trial compares restricted versus liberal fluid administration for hemodynamic resuscitation in septic shock, with stat…
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Efficacy and Safety of Methylene Blue in the Treatment of Severe Septic Shock [NA]
A clinical trial is evaluating the efficacy and safety of methylene blue for the treatment of severe septic shock and is currently recruitin…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Use of Epoetin Alfa and Iron Derisomaltose in Treatment of Anemia in Patients With Sepsis or Septic Shock: a Randomized Controlled Trial [Phase 4]
Phase 4 randomized controlled trial evaluating epoetin alfa with iron isomaltose for treating anemia in patients with sepsis or septic shock…
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: Role of Ivabradine for Heart Rate Control in Management of Patients With Sepsis and Septic Shock [NA]
A clinical trial is evaluating ivabradine for heart rate control in patients with sepsis and septic shock; the study status is not yet recru…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: Fever Control Using External Cooling in Mechanically Ventilated Patients With Septic Shock [NA]
Clinical trial investigating external cooling to control fever in mechanically ventilated patients with septic shock; currently recruiting.
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Hemodynamic Phenotype-Based,Capillary Refill Time-Targeted Resuscitation In Early Septic Shock:ANDROMEDA-SHOCK-2 [NA]
The ANDROMEDA-SHOCK-2 trial evaluating hemodynamic phenotype-based, capillary refill time-targeted resuscitation in early septic shock is cu…
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock [Phase 2]
Phase 2 clinical trial evaluating umbilical cord-derived mesenchymal stromal cells as cellular immunotherapy for septic shock, currently rec…
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Efficacy and Safety of Hemoperfusion With Polymyxin B in Septic Shock Associated With Severe Endotoxemia in Cardiac Surgery Patients (РМХ vs SS) [NA]
A recruiting clinical trial evaluating hemoperfusion with Polymyxin B for septic shock associated with severe endotoxemia in cardiac surgery…