Progressive Multiple Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Multiple Sclerosis-Simvastatin Trial 2 [Phase 3]
Phase 3 trial evaluating simvastatin for secondary progressive multiple sclerosis has completed.
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Real-world Study to Assess the Use of Siponimod in Spain to Treat Patients With Secondary Progressive Multiple Sclerosis
A completed real-world study conducted in Spain evaluating the use of siponimod for secondary progressive multiple sclerosis.
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Study to Assess Changes in Immunoglobulins in Patients With Relapsing Multiple Sclerosis Treated With Anti-CD20 Therapies
A completed study evaluating changes in immunoglobulin levels in patients with relapsing multiple sclerosis treated with anti-CD20 therapies…
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CLINICAL_TRIALS research · 2024-07-24Clinical Trial Update: Development of Camera Based Gait Quality Measure for Persons With Multiple Sclerosis
This trial update describes the development of a camera-based gait quality measure for people with multiple sclerosis and notes that recruit…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Telerehabilitation in Progressive Multiple Sclerosis [NA]
A telerehabilitation clinical trial for progressive multiple sclerosis, sponsored by Universita di Verona, has not yet started recruiting.
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FDA approval · 2024-06-05FDA Approved: MAYZENT — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for Mayzent (siponimod) submitted by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Study to Explore the Mechanism of Action of Ocrelizumab and B-Cell Biology in Participants With Relapsing Multiple Sclerosis (RMS) or Primary Progressive Multiple Sclerosis (PPMS) [Phase 3]
Phase 3 study exploring the mechanism of action of ocrelizumab and B-cell biology in relapsing and primary progressive multiple sclerosis; r…
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CLINICAL_TRIALS research · 2024-05-21Clinical Trial Update: Serial Collection of Primary Progressive Multiple Sclerosis Participants in the MURDOCK Study
This update reports the completion of serial collection from participants with Primary Progressive Multiple Sclerosis in the MURDOCK study.
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Exploring the Immune Response to SARS-CoV-2 modRNA Vaccines in Patients With Secondary Progressive Multiple Sclerosis (AMA-VACC) [Phase 4]
Phase 4 AMA-VACC trial results assess the immune response to SARS-CoV-2 modRNA vaccines in patients with secondary progressive multiple scle…
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: Remote Ischemic Conditioning in PPMS [NA]
A clinical trial is evaluating remote ischemic conditioning for primary progressive multiple sclerosis and is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: A Study to Assess the Effectiveness and Safety of Mayzent in Chinese Patients With Relapsing Forms of Multiple Sclerosis
This clinical trial update reports the completion of a study evaluating the effectiveness and safety of Mayzent (fingolimod) in Chinese pati…
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CLINICAL_TRIALS trial_result · 2023-11-09Clinical Trial Update: Phase II Clinical Trial of OCH-NCNP1 [Phase 2]
Phase II clinical trial update for OCH-NCNP1 completed; study conditions include relapsing-remitting and secondary progressive multiple scle…
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CLINICAL_TRIALS trial_result · 2023-09-06Clinical Trial Update: Effect of Ocrelizumab on Brain Innate Immune Microglial Cells Activation in MS Using PET-MRI With 18F-DPA714 [Phase 3]
Phase 3 trial exploring ocrelizumab's effect on brain innate immune microglial activation in multiple sclerosis using PET-MRI.
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FDA approval · 2023-08-18FDA Approved: OCREVUS — Supplemental Application (Genentech, Inc.)
The FDA approved a supplemental application for Ocrevus (ocrelizumab) from Genentech, Inc. The action expands the drug's approved indication…
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CLINICAL_TRIALS trial_result · 2023-05-03Clinical Trial Update: A Trial of Bile Acid Supplementation in Patients With Multiple Sclerosis [Phase 1, Phase 2]
A combined Phase 1/2 trial evaluating bile acid supplementation in progressive multiple sclerosis has been completed with posted results.
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CLINICAL_TRIALS trial_result · 2023-03-10Clinical Trial Update: Intranasal Insulin for Improving Cognitive Function in Multiple Sclerosis [Phase 1, Phase 2]
Clinical trial update for intranasal insulin in multiple sclerosis across Phase 1 and Phase 2 has been completed with results posted.
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FDA approval · 2022-06-21FDA Approved: MAYZENT — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA granted approval of a supplemental application for MAYZENT (siponimod) from Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2022-02-14Clinical Trial Update: G-EO Gait Rehabilitation Training in Progressive Multiple Sclerosis [NA]
Clinical trial update for G-EO Gait Rehabilitation Training in progressive multiple sclerosis; study completed with posted results in 2022.
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FDA approval · 2021-09-10FDA Approved: MAYZENT — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for Mayzent (siponimod) by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2021-07-09Clinical Trial Update: A Study of the Effectiveness of Fampridine in Improving Upper Limb Function in MS [Phase 4]
Phase 4 trial assessing the effectiveness of fampridine in improving upper limb function in people with secondary progressive and primary pr…
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CLINICAL_TRIALS research · 2021-05-19Clinical Trial Update: Idebenone for Primary Progressive Multiple Sclerosis [Phase 1, Phase 2]
Clinical trial update on idebenone for primary progressive multiple sclerosis completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-03-08Clinical Trial Update: Patient Research Cohort: Rapidly Evolving Multiple Sclerosis
A completed clinical trial update from Imperial College London on a patient research cohort for Relapsing-remitting and Secondary Progressiv…
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CLINICAL_TRIALS trial_result · 2020-12-24Clinical Trial Update: Dimethyl Fumarate Treatment of Primary Progressive Multiple Sclerosis [Phase 2]
Phase 2 clinical trial update for dimethyl fumarate in primary progressive multiple sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2020-07-28Clinical Trial Update: Safety, Tolerability and Activity Study of Ibudilast in Subjects With Progressive Multiple Sclerosis [Phase 2]
Phase 2 trial update on ibudilast in progressive multiple sclerosis assessing safety, tolerability, and activity.
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FDA label_change · 2020-05-15FDA Approved: OCREVUS — Supplemental Application (Genentech, Inc.)
FDA approved a supplemental application for Ocrevus (ocrelizumab) from Genentech, Inc., resulting in labeling changes for its multiple scler…