Progressive Multiple Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis [Phase 3]
A Phase 3 trial evaluating remibrutinib for efficacy and safety in secondary progressive multiple sclerosis is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Ocrelizumab in Participants With Relapsing Multiple Sclerosis and Primary Progressive Multiple Sclerosis [Phase 4]
This Phase 4 clinical trial is evaluating the efficacy, safety, pharmacokinetics, and pharmacodynamics of ocrelizumab in participants with R…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Serum GFAP, NfL, VEGF and Clinical Progression in Progressive MS
This clinical trial update from Ondokuz Mayıs University investigates serum biomarkers GFAP, NfL, and VEGF and their relation to clinical pr…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Safety and Efficacy of Extracorporeal Photopheresis (ECP) in the Treatment of Multiple Sclerosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial is assessing the safety and efficacy of Extracorporeal Photopheresis for Multiple Sclerosis, including Relapsing-…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Functional Outcomes From Diets in Multiple Sclerosis [NA]
This clinical trial update reports on functional outcomes from dietary interventions in people with relapsing-remitting multiple sclerosis a…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS) [Phase 3]
A Phase 3 study to evaluate the efficacy, safety, and pharmacokinetics of a higher dose of ocrelizumab in adults with primary progressive mu…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple Sclerosis [Phase 3]
A Phase 3 trial compares fenebrutinib to ocrelizumab in adults with primary progressive multiple sclerosis; the study status is ACTIVE_NOT_R…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Obe-cel in Refractory Progressive Forms of Multiple Sclerosis [Phase 1]
A Phase 1 clinical trial update indicates Obecel (Obe-cel) for refractory progressive multiple sclerosis is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis [Phase 3]
Phase 3 clinical trial investigating Orelabrutinib for secondary progressive multiple sclerosis is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Intermittent Hypoxia in Persons With Multiple Sclerosis [NA]
A clinical trial update indicates a study evaluating intermittent hypoxia in people with Multiple Sclerosis is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial sponsored by Tr1X, Inc. is currently recruiting to evaluate a treatment for Primary Progressive Multiple Sclerosi…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: The Effect of Rituximab on Cognitive and Hand Functions in Secondary Progressive Multiple Sclerosis [Phase 2]
Phase 2 clinical trial assessing rituximab for cognitive and hand function in secondary progressive multiple sclerosis. The study is current…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Study of Mesenchymal Autologous Stem Cells as Regenerative Treatment for Multiple Sclerosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating autologous mesenchymal stem cells as a regenerative treatment for multiple sclerosis, currently active…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Neuroprotection With N-acetyl Cysteine for Patients With Progressive Multiple Sclerosis [Phase 2]
Phase 2 study evaluating N-acetylcysteine for neuroprotection in progressive multiple sclerosis; currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: The Synergistic Effects of AIH and FES in Persons With MS [NA]
This clinical trial update covers a study evaluating the synergistic effects of AIH and Functional Electrical Stimulation (FES) in people wi…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Bringing the Outdoors In: Virtual Nature Walks for Depression in Multiple Sclerosis (MS) Patients [NA]
A University of Michigan–led clinical trial is recruiting to test whether virtual nature walks can alleviate depressive symptoms in people w…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis [Phase 3]
This document describes an ongoing Phase 3 clinical trial evaluating ocrelizumab in participants with progressive multiple sclerosis, with t…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: A Study of KYV-101, a CD19 CAR T Cell Therapy, in Participants With Treatment Refractory Progressive Multiple Sclerosis [Phase 1]
Phase 1 study update on KYV-101, a CD19 CAR T cell therapy, for treatment-refractory Progressive Multiple Sclerosis, with the trial currentl…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Home Based Functional Balance Intervention for Multiple Sclerosis [NA]
A clinical trial is recruiting to evaluate a home-based functional balance intervention for people with multiple sclerosis. The study appear…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS) [Phase 3]
BEAT-MS is a Phase 3 trial comparing best available therapy to autologous hematopoietic stem cell transplantation for multiple sclerosis; it…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Clinnova-MS: A Prospective Cohort Study of Patients With Multiple Sclerosis: A Trans-regional Digital Health Effort Unlocking the Potential of Artificial Intelligence and Data Science in Health Care
A prospective cohort study called Clinnova-MS investigates AI and data science applications in health care for various forms of multiple scl…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Allogenic Adipose Tissue-derived Mesenchymal Stromal Cells for the Treatment of Primary Progressive Multiple Sclerosis [Phase 1]
A Phase 1 clinical trial investigating allogeneic adipose tissue–derived mesenchymal stromal cells for primary progressive multiple sclerosi…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Study of Circadian Focused Light Therapy in Progressive Multiple Sclerosis [Phase 1]
A Phase 1 study evaluating circadian-focused light therapy for progressive multiple sclerosis is currently enrolling by invitation, sponsore…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Senolytics for Secondary Progressive MS [Phase 1]
A Phase 1 clinical trial evaluating senolytic therapies for secondary progressive multiple sclerosis, sponsored by Ohio State University; th…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Open-label, Multi-center, Phase I/II Study to Assess Safety, Disease Progression and Cellular Kinetics Following YTB323 Administration in Participants With Non-active Progressive Multiple Sclerosis (PMS) [Phase 1, Phase 2]
Open-label Phase 1/2 clinical trial assessing safety, disease progression and cellular kinetics of YTB323 in participants with non-active pr…