Richter Transformation
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Study of Brexucabtagene Autoleucel in Adults With Rare B-cell Malignancies [Phase 2]
Phase 2 trial of Brexucabtagene Autoleucel in adults with rare B-cell malignancies has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: Study of a Triple Combination Therapy, DTRM-555, in Patients With R/R CLL or R/R Non-Hodgkin's Lymphomas [Phase 2]
A Phase 2 study evaluating the triple combination therapy DTRM-555 in relapsed/refractory chronic lymphocytic leukemia and relapsed/refracto…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Study of TG-1801 Alone or in Combination With Ublituximab in Subjects With B-Cell Lymphoma or Chronic Lymphocytic Leukemia [Phase 1]
Phase 1 study assessing TG-1801 alone or with ublituximab in patients with CLL, SLL, and other B-cell lymphomas was terminated.
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CLINICAL_TRIALS trial_result · 2024-03-20Clinical Trial Update: Nivolumab and Ibrutinib in Treating Patients With Relapsed, Refractory, or High-Risk Untreated Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Richter Transformation [Phase 2]
Phase 2 trial evaluating nivolumab and ibrutinib in relapsed/refractory or high-risk untreated chronic lymphocytic leukemia, small lymphocyt…
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CLINICAL_TRIALS trial_result · 2023-02-17Clinical Trial Update: Ibrutinib, Nivolumab and Blinatumomab in Richter Transformation [Phase 2]
Phase 2 trial evaluating a combination of ibrutinib, nivolumab, and blinatumomab in Richter transformation has been terminated; results post…
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CLINICAL_TRIALS trial_result · 2022-05-06Clinical Trial Update: ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies [Phase 1, Phase 2]
Phase 1/2 trial of acalabrutinib (ACP-196) in combination with pembrolizumab in hematologic malignancies has completed with results posted i…
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CLINICAL_TRIALS trial_result · 2021-08-05Clinical Trial Update: R-EPOCH in Combination With Ibrutinib for Patients With Classical RT of CLL [Phase 2]
Phase 2 trial evaluating R-EPOCH with Ibrutinib for Richter Transformation in chronic lymphocytic leukemia, status unknown.
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CLINICAL_TRIALS trial_result · 2021-01-06Clinical Trial Update: A Study of Acalabrutinib and Vistusertib in Subjects With Relapsed/Refractory B-cell Malignancies [Phase 1, Phase 2]
Phase 1/2 trial of acalabrutinib plus vistusertib in relapsed/refractory B-cell malignancies (DLBCL and Richter syndrome) was terminated.
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CLINICAL_TRIALS trial_result · 2020-03-10Clinical Trial Update: PNT2258 for Treatment of Patients With Richter's Transformation (Brighton) [Phase 2]
Phase 2 trial update for PNT2258 in Richter's transformation has been terminated with posted results.
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CLINICAL_TRIALS trial_result · 2020-02-11Clinical Trial Update: Selinexor in Initial or Refractory and/or Relapsed Richter's Transformation [Phase 2]
Phase 2 clinical trial update for selinexor in Richter's transformation (initial or refractory/relapsed); study terminated with results post…
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CLINICAL_TRIALS trial_result · 2016-10-03Clinical Trial Update: Combination Chemotherapy and Rituximab in Treating Patients With Chronic Lymphocytic Leukemia (CLL) That Did Not Respond to Fludarabine, CLL With Autoimmune Haemolytic Anemia (AIHA) or Richter's Transformation (RT) [Phase 2]
Phase 2 trial evaluating rituximab-based combination chemotherapy in patients with chronic lymphocytic leukemia that did not respond to flud…
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CLINICAL_TRIALS trial_result · 2011-08-29Clinical Trial Update: Oxaliplatin, Fludarabine, Cytarabine and Rituximab in Richter's Syndrome, Refractory CLL and PLL [Phase 1, Phase 2]
A Phase 1/2 study evaluating oxaliplatin, fludarabine, cytarabine, and rituximab in Richter's syndrome and refractory chronic lymphocytic le…