Richter Transformation
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Study of BGB-21447, a Bcl-2 Inhibitor, in Mature B-Cell Malignancies [Phase 1]
Phase 1 clinical trial update of BGB-21447, a Bcl-2 inhibitor developed by BeOne Medicines, evaluating safety and preliminary activity in mu…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Study of Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006) [Phase 2]
This clinical trial update reports on a Phase 2 study of Zilovertamab Vedotin (MK-2140) as monotherapy and in combination for aggressive and…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: CD45BE-HSPC + CART-45 Cells [Phase 1]
Phase 1 study evaluating CD45BE-HSPC with CART-45 cells is not yet recruiting and targets B-cell non-Hodgkin lymphoma and Richter transforma…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-naïve Chronic Lymphocytic Leukemia (CLL) or Richter Transformation (RT) [Phase 2]
A Phase 2 clinical trial is evaluating a time-limited triplet therapy of pirtobrutinib, venetoclax, and obinutuzumab for treatment-naïve chr…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: ONO-4538 Study in Patients With Richter's Transformation [Phase 2]
Phase 2 clinical trial of ONO-4538 (nivolumab) in patients with Richter's transformation is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Phase 2 Study of Glofitamab Monotherapy & With Polatuzumab Vedotin, Pirtobrutinib, or Atezolizumab in Richter's Transformation [Phase 2]
Phase 2 clinical trial evaluating glofitamab as monotherapy and in combination with polatuzumab vedotin, pirtobrutinib, or atezolizumab for …
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Efficacy and Safety of Zanubrutinib Plus Tislelizumab Treatment with or Without Sonrotoclax for Patients with Richter Transformation [Phase 2]
Phase 2 clinical trial evaluating zanubrutinib plus tislelizumab with or without sonrotoclax for Richter transformation; currently recruitin…