Retinitis Pigmentosa
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CLINICAL_TRIALS trial_result · 2026-06-05Clinical Trial Update: A Study of AAV5-hRKp.RPGR for the Treatment of Japanese Participants With X-linked Retinitis Pigmentosa [Phase 3]
Phase 3 trial update for AAV5-hRKp.RPGR in Japanese participants with X-linked Retinitis Pigmentosa (inactive/recruiting status noted).
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Cell Collection to Study Eye Diseases
An NEI-sponsored clinical trial update describes cell collection to study eye diseases, including age-related macular degeneration, retinal …
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: A Study in Subjects With Retinitis Pigmentosa [Phase 2]
Phase 2 trial in Retinitis Pigmentosa completed; results have been posted by Aldeyra Therapeutics.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Impact of Capsular Tension Ring on Intraocular Lens Position in Retinitis Pigmentosa Cataract Patients [NA]
Clinical trial update on whether a capsular tension ring affects intraocular lens position in cataract patients with retinitis pigmentosa. T…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Observational Study to Investigate the Short-term Effects of Transcorneal Electrical Stimulation on Visual Performance
An observational trial update evaluating the short-term effects of transcorneal electrical stimulation on visual performance in patients wit…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Rod and Cone Mediated Function in Retinal Disease
Clinical trial registry entry for a study of rod and cone mediated function in retinal disease, sponsored by the National Eye Institute, cur…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years of Age or Older With Retinitis Pigmentosa [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the safety of DSP-3077 given by unilateral intravitreal injection in adults with retinitis pigmento…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants
A registry and natural history study investigating retinal dystrophies associated with rare disease-causing genetic variants; currently recr…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Prospective, Randomized, Sham-controlled, Dose-finding I/II Trial of Safety and Efficacy of Modified Optogenetic Gene Therapy (ZM-02 Injection) [Phase 1, Phase 2]
A Phase 1/2 prospective, randomized, sham-controlled dose-finding trial assessing the safety and efficacy of ZM-02 Injection, a modified opt…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: SAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects [Phase 1]
Phase 1 study of intravitreal VP-001 in PRPF31 mutation-associated retinal dystrophy (RP11) has completed; no detailed results are provided …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Natural History of PRPF31 Mutation-Associated Retinal Dystrophy
This clinical trial update describes an ongoing natural history study of PRPF31 mutation-associated retinal dystrophy, an inherited retinal …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Safety of a Single, Intravitreal Injection of 6.0M jCell (Famzeretcel) in Retinitis Pigmentosa (RP) [Phase 2]
Phase 2 clinical trial evaluating the safety of a single intravitreal injection of jCell (Famzeretcel) for Retinitis Pigmentosa; the study i…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO) [Phase 1, Phase 2]
This clinical trial update reports that recruitment is ongoing for a Phase 1/2 study evaluating the safety of OpCT-001 in adults with primar…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: CNGB1 and Allied Disorders
The CNGB1-related retinitis pigmentosa clinical trial has been suspended.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Expanded Access Program for RP in Adults
The document notes that the expanded access program for Ocugen's retinitis pigmentosa treatment in adults is no longer available.
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: 9-cis Beta-Carotene-Rich Extract of Dunaliella Alga in Retinitis Pigmentosa Patients [Phase 1, Phase 2]
A Phase 1/2 trial of a 9-cis beta-carotene-rich extract from Dunaliella algae in retinitis pigmentosa is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Restoration of Central Vision With PRIMA in Patients With Photoreceptor Degeneration [NA]
A clinical trial evaluating PRIMA for photoreceptor degeneration is currently recruiting, focusing on Stargardt disease and retinitis pigmen…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Development and Evaluation of Functional Visual Field and Navigation Endpoints in Moderate to Profound Inherited Retinal Disease (DEFINE-IRD)
Clinical trial update on the development and evaluation of functional visual field and navigation endpoints for moderate-to-profound inherit…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Safety and Efficacy Study of Novel Gene Therapy ZM-02 for Retinitis Pigmentosa Patients [EARLY_Phase 1]
An early-phase trial evaluating the safety and potential efficacy of the novel gene therapy ZM-02 in patients with retinitis pigmentosa, cur…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Study to Evaluate Ultevursen in Subjects With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene [Phase 2]
Ultevursen is being evaluated in a Phase 2 trial for retinitis pigmentosa caused by USH2A exon 13 mutations, and recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Subtenon Autologous Platelet-Rich Plasma in Inherited and Degenerative Retinal Diseases [Phase 1, Phase 2]
This clinical trial update notes a Phase 1/Phase 2 study evaluating subtenon autologous platelet-rich plasma for inherited and degenerative …
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Intravitreal Adalimumab in Inherited and Degenerative Retinal Diseases [Phase 1, Phase 2]
This clinical trial update covers an intravitreal adalimumab study for inherited and degenerative retinal diseases, including Retinitis Pigm…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: A Phase 3 Study Of OCU400 Gene Therapy for the Treatment Of Retinitis Pigmentosa [Phase 3]
Ocugen reports a Phase 3 trial of the OCU400 gene therapy for retinitis pigmentosa is active but not recruiting.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Rate of Progression in EYS Related Retinal Degeneration
Clinical trial update on the rate of progression in EYS-related retinal degeneration (Retinitis Pigmentosa); the study is active but not rec…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Dose-escalation Study to Evaluate the Safety and Tolerability of GS030 in Subjects With Retinitis Pigmentosa [Phase 1, Phase 2]
GenSight Biologics is conducting a dose-escalation Phase 1/2 trial of GS030 to evaluate safety and tolerability in non-syndromic Retinitis P…