Retinitis Pigmentosa
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Oral N-acetylcysteine for Retinitis Pigmentosa [Phase 3]
Phase 3 trial of oral N-acetylcysteine for Retinitis Pigmentosa is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Prospective, Observational Study in Adults With Retinitis Pigmentosa (RP)
Prospective observational study in adults with Retinitis Pigmentosa, sponsored by Sumitomo Pharma America, currently active but not recruiti…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Electro-acupuncture and Transcorneal Electrical Stimulation (TES) for Retinitis Pigmentosa [NA]
Clinical trial update noting an ongoing study evaluating electro-acupuncture and transcorneal electrical stimulation for retinitis pigmentos…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Role of UC-MSC and CM to Inhibit Vision Loss in Retinitis Pigmentosa Phase I/II [Phase 2, Phase 3]
Clinical trial update on using Umbilical Cord Mesenchymal Stem Cells (UC-MSC) and conditioned media (CM) to slow vision loss in Retinitis Pi…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Long-term Safety of UC-MSC Transplantation in Patients With Retinitis Pigmentosa
This clinical trial update describes a study assessing the long-term safety of umbilical cord-derived mesenchymal stem cell (UC-MSC) transpl…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Study to Evaluate Safety of RTx-015 Injection in Retinitis Pigmentosa or Choroideremia Patients (ENVISION) [Phase 1]
ENVISION is a Phase 1 trial evaluating the safety of RTx-015 injection in patients with retinitis pigmentosa or choroideremia; the study is …
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EMA approval · 2026-02-16EMA Authorised: Luxturna (voretigene neparvovec) — Novartis Europharm Limited
The European Medicines Agency authorised Luxturna (voretigene neparvovec) from Novartis Europharm Limited for the treatment of inherited ret…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: A Phase 1/2 Study in Healthy Volunteers and Participants With Autosomal Dominant Retinitis Pigmentosa (RHO-adRP) [Phase 1, Phase 2]
A Phase 1/2 clinical trial sponsored by Octant, Inc. is recruiting healthy volunteers and participants with autosomal dominant retinitis pig…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Implementation and Evaluation of a Post-Diagnostic Announcement Protocol at the CRMR RefeRet, Quinze-Vingts Hospital [NA]
This entry reports a clinical trial at Quinze-Vingts Hospital evaluating a post-diagnostic announcement protocol for retinitis pigmentosa; t…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F
This update describes a clinical trial evaluating the rate of progression of PCDH15-related retinal degeneration in Usher syndrome type 1F; …
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Rate of Progression in USH2A-related Retinal Degeneration
This clinical trial update indicates a study on the rate of progression in USH2A-related retinal degeneration is active but not currently re…
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Clinical Trial of Autologous Intravitreal Bone-marrow CD34+ Stem Cells for Retinopathy [Phase 1]
Phase 1 trial update on autologous intravitreal CD34+ stem cells for retinopathy; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: BS01 in Patients With Retinitis Pigmentosa [Phase 1, Phase 2]
BS01 is being studied in a Phase 1/2 clinical trial for Retinitis Pigmentosa and is currently recruiting. The sponsor and developer is Bioni…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment [NA]
This clinical trial update from the University of Waterloo describes a brain stimulation study to assess orientation and mobility in adults …
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: A First-in-human, Proof of Concept Study of CPK850 in Patients With RLBP1 Retinitis Pigmentosa [Phase 1, Phase 2]
This document reports a first-in-human, Phase 1/2 study of CPK850 for RLBP1-related Retinitis Pigmentosa, sponsored by Novartis, which is cu…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Non-invasive Ultrasound Retinal Stimulation for Vision Restoration [NA]
A USC-led clinical trial is evaluating non-invasive ultrasound retinal stimulation as a potential vision-restoration therapy for Age-Related…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: UGX202 Injection in Patients With Advanced Retinitis Pigmentosa [EARLY_Phase 1]
This entry reports an early-phase 1 clinical trial of UGX202 in patients with advanced Retinitis Pigmentosa, with status not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Wide Field OCTA in Ocular Diseases
Clinical trial update on a wide-field optical coherence tomography angiography (OCTA) study across several ocular diseases, sponsored by IRC…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Safety and Efficacy of NPI-001 Tablets for RP Associated With Usher Syndrome [Phase 1, Phase 2]
This document provides an update on a Phase 1/2 clinical trial of NPI-001 tablets for retinitis pigmentosa associated with Usher syndrome, c…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: 24-Month Trial of NPI-001 for the Preservation of Photoreceptors in Retinitis Pigmentosa Associated With Usher Syndrome [Phase 3]
Phase 3 clinical trial update for NPI-001 aimed at preserving photoreceptors in retinitis pigmentosa associated with Usher syndrome; the stu…
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Safety and Efficacy Study in Patients With Retinitis Pigmentosa Due to Mutations in PDE6B Gene [Phase 1, Phase 2]
The Phase 1/2 trial evaluating eyeDNA Therapeutics’ PDE6B gene therapy for retinitis pigmentosa caused by PDE6B mutations has been terminate…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Repository for Inherited Eye Diseases
Completed update on the Repository for Inherited Eye Diseases by the National Eye Institute, describing resources related to Retinitis Pigme…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Inherited Retinal Diseases: Natural History and Genotype-Phenotype Correlations
This clinical trial update describes inherited retinal diseases, focusing on natural history and genotype-phenotype correlations, with the s…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001 [Phase 1, Phase 2]
A two-arm, repeat-dose, open-label Phase 1/2 trial evaluating two intravitreal doses of VP-001 in participants with PRPF31 mutation-associat…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: A Phase I/II Dose-escalating Study of the Safety, Tolerability and Efficacy of KIO-301 Administered Intravitreally to Patients With Retinitis Pigmentosa and Choroideremia (ABACUS) [Phase 1, Phase 2]
An early-phase (Phase 1/2) dose-escalation study is investigating intravitreal KIO-301 for Retinitis pigmentosa and choroideremia; the trial…