Rem Sleep Behavior Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: The Swedish BioFINDER Sleep Study
The Swedish BioFINDER Sleep Study is currently recruiting participants, sponsored by Skane University Hospital. It focuses on Parkinson's di…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD) [Phase 2]
Phase 2 exploratory study sponsored by Yale University to test whether manipulating the immune system can prevent the emergence of synuclein…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic Disorders [NA]
Clinical trial update for a study of Ultra-High Resolution PET imaging in aging, neurodegeneration and psychotic disorders; recruitment is o…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Implementing a National Biobank of PD With WGS and Functional Assessment of Polygenic Inheritance by iPSC Technology
This clinical trial update outlines the development of a national biobank for Parkinson's disease using whole-genome sequencing and iPSC-bas…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Unmet Needs Among Patients With Isolated REM Sleep Behavior Disorder (iRBD) and Their Significant Others
A recruiting study at Universita di Verona aims to understand unmet needs of people with isolated REM Sleep Behavior Disorder and their sign…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Understanding Alpha-Synuclein Spread in Parkinson's Disease Through Blood Biomarkers and Neuroimaging [NA]
A university-led trial is investigating how alpha-synuclein spreads in Parkinson's disease using blood biomarkers and neuroimaging, with rec…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Parkinson's Disease Biomarker Study
A completed clinical trial update on a biomarker study related to idiopathic Parkinson disease and REM sleep behavior disorder.
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Behavioral Treatment for Nightmares in REM Sleep Behavior Disorder [NA]
This clinical trial is evaluating a behavioral treatment for nightmares in REM sleep behavior disorder. Recruitment is currently ongoing.
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CLINICAL_TRIALS other · 2026-03-10Clinical Trial Update: DaTSCAN Imaging in Aging and Neurodegenerative Disease [Phase 4]
An update on a Phase 4 clinical trial evaluating DaTSCAN imaging in aging and neurodegenerative diseases, currently enrolling by invitation.
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Study of Sleep Disorders in Prodromal and Definite Parkinsons Disease [NA]
This clinical trial update indicates a study investigating sleep disorders in prodromal and diagnosed Parkinson's disease, including REM sle…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: IMPACT 360 for Parkinson's Disease [Phase 2]
A Phase 2 clinical trial update for IMPACT 360 in Parkinson's disease and REM sleep behavior disorder. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Terazosin Effect on Cardiac Changes in Early Parkinson's Disease [Phase 2]
Phase 2 clinical trial evaluating whether terazosin affects cardiac changes in early Parkinson's disease. The study includes participants wi…
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Cardiac Changes in Early Parkinson's Disease: A Follow up Study [Phase 2]
A Phase 2 follow-up study reports updates on cardiac changes in early Parkinson disease, involving individuals with REM sleep behavior disor…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Adrenergic Blockers for Cardiac Changes in Early Parkinson's Disease (Protocol 53136) [Phase 2]
A Phase 2 clinical trial protocol is described for evaluating adrenergic blockers to address cardiac changes in early Parkinson's disease, i…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Terazosin and Parkinson's Disease Extension Study [Phase 2]
This clinical trial update covers a Phase 2 extension study of terazosin for symptomatic Parkinson's disease and REM sleep behavior disorder…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Role of Slow Waves in the Progression of Neurodegeneration in Isolated REM Sleep Behavior Disorder [NA]
A university-sponsored clinical trial is investigating the role of slow brain waves in the progression of neurodegeneration in isolated REM …
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Colonic Tissue Biopsy Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis or REM Sleep Behavior Disorder
A clinical trial is evaluating colonic tissue biopsy to detect phosphorylated alpha-synuclein as a potential diagnostic biomarker for Parkin…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Quantification of Phosphorylated Alpha-synuclein in Cutaneous Biopsies as a Prospective Biomarker in Parkinson's Disease
This clinical trial update describes a prospective study quantifying phosphorylated alpha-synuclein in skin biopsies as a potential biomarke…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Development and Online Evaluation of an Online Course for Parasomnias [NA]
A University of Manitoba-led clinical trial is developing and online-evaluating an online course for parasomnias. Recruitment is ongoing for…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Microstructural and Sodium 7 Tesla Brain MRI in Idiopathic REM Sleep Behaviour Disorder [NA]
This is a completed clinical trial update investigating microstructural and sodium 7 Tesla brain MRI in idiopathic REM sleep behavior disord…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: INSIGHT: Insomnia, Nightmares, and Sympathetic Hyperactivity Intervention [NA]
This clinical trial update announces the INSIGHT study evaluating an intervention for insomnia, nightmares, and sympathetic activation, with…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: PET-MRI of Reward System in Parkinson's Disease With RBD [NA]
A clinical trial update for a PET-MRI study of the reward system in Parkinson's disease with REM sleep behavior disorder, currently not yet …
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: The Effects of Tasimelteon in Participants With REM Behavior Disorder (RBD) [EARLY_Phase 1]
The early-phase trial evaluating tasimelteon for REM sleep behavior disorder has been terminated. No results are provided in the update.
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Molecular Imaging of Inflammation in Parkinson's Disease Using LPS and TSPO-PET/MR
A University of Exeter-led clinical trial is exploring molecular imaging of inflammation in Parkinson's disease using LPS and TSPO-PET/MR; t…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: MIBG in Aging and Neurologic Disorders [Phase 4]
Mayo Clinic is leading a Phase 4 trial of MIBG in aging and neurologic disorders, with enrollment by invitation, studying Lewy body dementia…