Rem Sleep Behavior Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Parkinson's Disease Biomarker Study
A completed clinical trial update on a biomarker study related to idiopathic Parkinson disease and REM sleep behavior disorder.
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Cardiac Changes in Early Parkinson's Disease: A Follow up Study [Phase 2]
A Phase 2 follow-up study reports updates on cardiac changes in early Parkinson disease, involving individuals with REM sleep behavior disor…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Microstructural and Sodium 7 Tesla Brain MRI in Idiopathic REM Sleep Behaviour Disorder [NA]
This is a completed clinical trial update investigating microstructural and sodium 7 Tesla brain MRI in idiopathic REM sleep behavior disord…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: INSIGHT: Insomnia, Nightmares, and Sympathetic Hyperactivity Intervention [NA]
This clinical trial update announces the INSIGHT study evaluating an intervention for insomnia, nightmares, and sympathetic activation, with…
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: The Effects of Tasimelteon in Participants With REM Behavior Disorder (RBD) [EARLY_Phase 1]
The early-phase trial evaluating tasimelteon for REM sleep behavior disorder has been terminated. No results are provided in the update.
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies
A terminated pilot biomarker study evaluating alpha-synuclein aggregates across biofluid reservoirs in synucleinopathies.
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Quantitative Mapping of Substantia Nigra Iron in Parkinson's Disease (Stages I-IV, REM Sleep Behavior Disorder) and Controls [Phase 1, Phase 2]
A Phase 1/2 clinical trial mapping iron levels in the substantia nigra across Parkinson disease, REM sleep behavior disorder, and healthy co…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Extended-Release Melatonin in Patients With Rapid Eye Movement Sleep Behavior Disorder [NA]
The clinical trial evaluating extended-release melatonin for REM sleep behavior disorder has been terminated. The study included participant…
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Treatment of REM Sleep Behavior Disorder (RBD) With Sodium Oxybate [Phase 4]
Phase 4 trial update evaluating sodium oxybate for REM Sleep Behavior Disorder with Parkinson's disease; study completed with results posted…
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CLINICAL_TRIALS trial_result · 2020-05-20Clinical Trial Update: Study Evaluating Nelotanserin for Treatment of REM Sleep Behavior Disorder in Subjects With Dementia (DLB or PDD) [Phase 2]
Phase 2 clinical trial evaluating nelotanserin for REM Sleep Behavior Disorder in patients with dementia-related conditions has completed wi…
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CLINICAL_TRIALS trial_result · 2018-03-16Clinical Trial Update: Exploration of the Reward System by Functional MRI in Parkinson's Disease Patients With and Without REM Sleep Behavior Disorder [NA]
A completed clinical trial studying the reward system using functional MRI in Parkinson's disease patients, with and without REM Sleep Behav…
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CLINICAL_TRIALS trial_result · 2017-04-28Clinical Trial Update: Effect of Slow-release Melatonin (Circadin®) Therapy on Idiopathic RBD: a Pilot Study [Phase 4]
Phase 4 pilot clinical trial evaluating slow-release Circadin melatonin for idiopathic REM sleep behavior disorder. The trial is sponsored b…
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CLINICAL_TRIALS trial_result · 2017-03-09Clinical Trial Update: Brain Imaging in the Idiopathic REM Sleep Behavior Disorder (ALICE)
This clinical trial update reports a completed study evaluating brain imaging in idiopathic REM sleep behavior disorder.
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CLINICAL_TRIALS trial_result · 2016-06-03Clinical Trial Update: Efficacy and Safety of Melatonin PR and Clonazepam in Patients With REM Sleep Behavior Disorder in Parkinson Disease [Phase 2]
Phase 2 trial evaluating the efficacy and safety of melatonin prolonged-release and clonazepam for REM sleep behavior disorder in Parkinson …
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CLINICAL_TRIALS trial_result · 2016-04-25Clinical Trial Update: Effect of Clonazepam on REM Sleep Behavior Disorder in Patients With Parkinsonism [Phase 2]
A Phase 2 clinical trial testing clonazepam for REM sleep behavior disorder in patients with Parkinsonism has completed.
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CLINICAL_TRIALS trial_result · 2011-07-25Clinical Trial Update: Study to Determine Whether Ramelteon Helps People With REM Sleep Behavior Disorder [Phase 4]
This ClinicalTrials.gov entry documents a Phase 4 trial evaluating ramelteon for REM sleep behavior disorder, which is reported as completed…
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CLINICAL_TRIALS trial_result · 2010-11-10Clinical Trial Update: Efficacy and Tolerability of Ramelteon in Patients With Rapid Eye Movement (REM) Behavior Disorder and Parkinsonism [NA]
A terminated clinical trial evaluated the efficacy and tolerability of ramelteon in patients with REM sleep behavior disorder and Parkinsoni…