Rem Sleep Behavior Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Predictors Of Cognitive Decline Using Digital Devices
A University College London trial investigates predictors of cognitive decline using digital devices across dementia, mild cognitive impairm…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Identification of Prodromal Neurodegeneration in Serotonergic-Induced REM Sleep Behavior Disorder [NA]
An update on a clinical trial studying prodromal neurodegeneration in serotonergic-induced REM sleep behavior disorder. The study is current…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Natural History Study of Synucleinopathies
An update on an ongoing natural history study of synucleinopathies, currently recruiting participants, including Parkinson's disease and rel…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-Netherlands [NA]
The Slow-SPEED-NL clinical trial in the Netherlands is currently recruiting to evaluate exercise dosage as an intervention for slowing early…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Neuroplasticity in RBD [NA]
A clinical trial is recruiting to study neuroplasticity in REM Sleep Behavior Disorder.
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Intestinal Immunity in Neurologic Disease
This clinical trial update describes a recruiting study from Yale University investigating intestinal immunity in neurologic diseases, inclu…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder [Phase 2]
A Phase 2 clinical trial update evaluating whether PXS-4728A modulates microglia activation in individuals with isolated REM sleep behavior …
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies
A terminated pilot biomarker study evaluating alpha-synuclein aggregates across biofluid reservoirs in synucleinopathies.
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Quantitative Mapping of Substantia Nigra Iron in Parkinson's Disease (Stages I-IV, REM Sleep Behavior Disorder) and Controls [Phase 1, Phase 2]
A Phase 1/2 clinical trial mapping iron levels in the substantia nigra across Parkinson disease, REM sleep behavior disorder, and healthy co…
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CLINICAL_TRIALS research · 2025-02-14Clinical Trial Update: The Impact of Light, Electrical, and Magnetic Neuroregulation Interventions on Sleep-wake Disorders [NA]
Clinical trial evaluating light, electrical, and magnetic neuroregulation interventions for sleep-wake disorders, currently recruiting at th…
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: The Syn-Sleep Study
The Syn-Sleep study (NCT05757206) sponsored by CND Life Sciences is currently active but not recruiting for REM sleep behavior disorder (idi…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Prodromal Model of Parkinson's Disease Confined to The Peripheral Nervous System
Enrollment by invitation is ongoing for a prodromal Parkinson's disease model confined to the peripheral nervous system.
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CLINICAL_TRIALS withdrawal · 2025-01-07Clinical Trial Update: Efficacy and Safety of Rasagiline in Prodromal Parkinson's Disease [Phase 2, Phase 3]
A Phase 2/3 trial of rasagiline for prodromal Parkinson disease, including REM sleep behavior disorder, has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-01-07Clinical Trial Update: A Study of Efficacy and Safety of Idebenone Vs. Placebo in Prodromal Parkinson Disease [Phase 2, Phase 3]
A study evaluating idebenone versus placebo in prodromal Parkinson disease and REM sleep behavior disorder has been withdrawn.
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Artificial Intelligence in Molecular Imaging: Predicting Parkinson's Risk in REM Sleep Behavior Disorder [NA]
A clinical trial update investigating the use of artificial intelligence applied to molecular imaging to predict Parkinson's disease risk in…
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CLINICAL_TRIALS research · 2024-11-06Clinical Trial Update: North American Prodromal Synucleinopathy Consortium
This update covers the North American Prodromal Synucleinopathy Consortium trial led by Washington University School of Medicine. Enrollment…
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CLINICAL_TRIALS research · 2024-11-06Clinical Trial Update: North American Prodromal Synucleinopathy Consortium Stage 2
This clinical trial update announces Stage 2 of the North American Prodromal Synucleinopathy Consortium, which is currently recruiting to st…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Extended-Release Melatonin in Patients With Rapid Eye Movement Sleep Behavior Disorder [NA]
The clinical trial evaluating extended-release melatonin for REM sleep behavior disorder has been terminated. The study included participant…
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CLINICAL_TRIALS research · 2024-05-20Clinical Trial Update: The COSP-RBD Study: Concussions and Contact Sports in RBD vs Controls
The COSP-RBD study is evaluating concussion outcomes in individuals with REM Sleep Behavior Disorder versus controls in contact-sport settin…
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CLINICAL_TRIALS other · 2024-05-13Clinical Trial Update: Subcortical Oscillations in Human Sleep Dysregulation
This clinical trial investigates subcortical brain oscillations in sleep dysregulation for Parkinson's disease and REM sleep behavior disord…
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Treatment of REM Sleep Behavior Disorder (RBD) With Sodium Oxybate [Phase 4]
Phase 4 trial update evaluating sodium oxybate for REM Sleep Behavior Disorder with Parkinson's disease; study completed with results posted…
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CLINICAL_TRIALS trial_result · 2020-05-20Clinical Trial Update: Study Evaluating Nelotanserin for Treatment of REM Sleep Behavior Disorder in Subjects With Dementia (DLB or PDD) [Phase 2]
Phase 2 clinical trial evaluating nelotanserin for REM Sleep Behavior Disorder in patients with dementia-related conditions has completed wi…
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CLINICAL_TRIALS research · 2018-05-17Clinical Trial Update: MRI Study of Brain Activity in Healthy Adults and Individuals With Parkinsonism and Rapid Eye Movement Disorder.
A completed MRI study examining brain activity in healthy adults and individuals with Parkinsonism and REM sleep behavior disorder.
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CLINICAL_TRIALS trial_result · 2018-03-16Clinical Trial Update: Exploration of the Reward System by Functional MRI in Parkinson's Disease Patients With and Without REM Sleep Behavior Disorder [NA]
A completed clinical trial studying the reward system using functional MRI in Parkinson's disease patients, with and without REM Sleep Behav…
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CLINICAL_TRIALS trial_result · 2017-04-28Clinical Trial Update: Effect of Slow-release Melatonin (Circadin®) Therapy on Idiopathic RBD: a Pilot Study [Phase 4]
Phase 4 pilot clinical trial evaluating slow-release Circadin melatonin for idiopathic REM sleep behavior disorder. The trial is sponsored b…