Pulmonary Hypertension
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CLINICAL_TRIALS withdrawal · 2026-01-27Clinical Trial Update: Pulmonary Vascular Hemodynamics Before and After Mitral Valve Procedures
Clinical trial NCT04947384 evaluating pulmonary vascular hemodynamics before and after mitral valve procedures has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-02-20Clinical Trial Update: CompRehensive Phenotypic Characterization of Patients With Scleroderma-Associated ILD and PH [Phase 2, Phase 3]
A Phase 2/Phase 3 trial evaluating comprehensive phenotypic characterization of patients with scleroderma-associated interstitial lung disea…
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CLINICAL_TRIALS withdrawal · 2024-11-22Clinical Trial Update: ADOPT: Improving Diagnosis of Pulmonary Hypertension With AI and Echo
The ADOPT trial, exploring AI and echocardiography to improve diagnosis of pulmonary hypertension, has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-06-03Clinical Trial Update: Rivet PVS Therapy in Group 2 PH-HFpEF [NA]
The trial investigating Rivet PVS Therapy for Group 2 pulmonary hypertension with heart failure with preserved ejection fraction has been wi…
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CLINICAL_TRIALS withdrawal · 2024-06-03Clinical Trial Update: Rivet PVS Therapy in Group 2 PH-HFpEF Canada [NA]
The Rivet PVS Therapy trial in Group 2 pulmonary hypertension associated with heart failure with preserved ejection fraction (HFpEF) in Cana…
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CLINICAL_TRIALS withdrawal · 2018-12-07Clinical Trial Update: Efficacy and Safety of Combination Ambrisentan and Tadalafil in Patients With Portopulmonary Hypertension [Phase 4]
Phase 4 trial evaluating ambrisentan plus tadalafil for portopulmonary hypertension has been withdrawn.
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EMA withdrawal · 2018-09-21EMA Application withdrawn: Treprostinil SciPharm Sàrl (treprostinil) — SciPharm Sàrl
The EMA indicates that the application for treprostinil by SciPharm Sàrl has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-07-05Clinical Trial Update: Imatinib and Carvedilol for High Blood Pressure in the Lungs in Adults With Sickle Cell Disease [Phase 1]
Phase 1 clinical trial of imatinib and carvedilol for pulmonary hypertension in adults with sickle cell disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-05-01Clinical Trial Update: Pulmonary Hypertension Secondary to Idiopathic Pulmonary Fibrosis And Treatment With Sildenafil [Phase 4]
Phase 4 trial evaluating sildenafil for pulmonary hypertension associated with idiopathic pulmonary fibrosis was withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-09-12Clinical Trial Update: Phosphodiesterase Type 5 Inhibition With Tadalafil Changes Outcomes in Heart Failure: Extent of Renal Damage [Phase 3]
A Phase 3 trial evaluating tadalafil for heart failure and pulmonary hypertension has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-05-15Clinical Trial Update: Study of the Effects of Iron on Lung Blood Pressure at High Altitude [Phase 2]
This Clinical Trial Update indicates that the Phase 2 study of the effects of iron on lung blood pressure at high altitude has been withdraw…
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CLINICAL_TRIALS withdrawal · 2017-04-11Clinical Trial Update: Safety and Tolerability of Inhaled Treprostinil in Adult PH Due to COPD [Phase 2]
A Phase 2 trial of inhaled treprostinil for adult pulmonary hypertension due to chronic obstructive pulmonary disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-01-11Clinical Trial Update: Noninvasive Cardiac Output Measurements in Patients With Pulmonary Hypertension Undergoing Right Heart Catheterization With Acute Vasodilator Testing
A clinical trial studying noninvasive cardiac output measurements in pulmonary hypertension patients undergoing right heart catheterization …
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CLINICAL_TRIALS withdrawal · 2016-11-16Clinical Trial Update: Immunoadsorption in Patients With Pulmonary Hypertension [Phase 1, Phase 2]
A Phase 1/2 immunoadsorption clinical trial in patients with pulmonary hypertension has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-09-09Clinical Trial Update: Inhaled Nitric Oxide (INO) In Hypoxic Respiratory Failure [Phase 3]
Phase 3 trial of inhaled nitric oxide for hypoxic respiratory failure with pulmonary hypertension has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-03-18Clinical Trial Update: Use of Inhaled Nitric Oxide to Prevent Pulmonary Hypertension Associated to Stored Blood Transfusion [Phase 2]
A Phase 2 trial evaluating inhaled nitric oxide to prevent pulmonary hypertension after stored blood transfusion has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-02-09Clinical Trial Update: Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Pulmonary Fibrosis [Phase 2]
A Phase 2 study of oral treprostinil for pulmonary hypertension associated with pulmonary fibrosis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-01-21Clinical Trial Update: The Role of Echocardiographic Contrast (Optison) in Enhancing Tricuspid Regurgitation Spectral Doppler Signals
A clinical trial evaluating the use of the ultrasound contrast agent Optison to enhance tricuspid regurgitation Doppler signals has been wit…
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CLINICAL_TRIALS withdrawal · 2015-12-23Clinical Trial Update: Noninvasive Cardiac Output Measurements in Patients With Pulmonary Hypertension Undergoing Exercise Testing
A clinical trial evaluating noninvasive cardiac output measurements in patients with pulmonary hypertension during exercise testing has been…
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CLINICAL_TRIALS withdrawal · 2015-12-02Clinical Trial Update: Evaluation of Pulmonary Doppler Signals in Patients With Systemic Sclerosis(SSc) [NA]
A clinical trial evaluating pulmonary Doppler signals in patients with Systemic Sclerosis and Pulmonary Hypertension has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-03-18Clinical Trial Update: Effect of Tadalafil in Chronic Obstructive Lung Disease Patients Suffering From Secondary Pulmonary Hypertension [NA]
A clinical trial evaluating tadalafil in COPD patients with secondary pulmonary hypertension has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-01-19Clinical Trial Update: Inhaled Iloprost as an Adjunct to Inhaled Nitric Oxide in Pediatric Critical Care Patients [Phase 1, Phase 2]
A pediatric phase 1/2 trial evaluating inhaled iloprost as an adjunct to inhaled nitric oxide for pulmonary hypertension and related neonata…
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CLINICAL_TRIALS withdrawal · 2013-07-29Clinical Trial Update: A Pilot Study of Chronic Red Blood Cell Transfusion in Sickle Cell Disease-Associated Pulmonary Hypertension [Phase 2]
Phase 2 pilot trial evaluating chronic red blood cell transfusions for sickle cell disease–associated pulmonary hypertension has been withdr…
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CLINICAL_TRIALS withdrawal · 2013-01-28Clinical Trial Update: Body Volume Regulation in Pulmonary Arterial Hypertension With Right Ventricular Failure [NA]
A University of Colorado, Denver trial investigating body volume regulation in pulmonary arterial hypertension with right ventricular failur…
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CLINICAL_TRIALS withdrawal · 2012-08-23Clinical Trial Update: Sildenafil for Chronic Obstructive Pulmonary Disease (COPD) Associated Pulmonary Hypertension [Phase 4]
This Phase 4 trial evaluating sildenafil for COPD-associated pulmonary hypertension has been withdrawn.