Pulmonary Hypertension
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot
A pilot study update on NeoDoppler, a new ultrasound technology for continuous monitoring of cerebral circulation in neonates, currently rec…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD [Phase 2]
Phase 2 clinical trial evaluating mosliciguat in combination with inhaled treprostinil for pulmonary hypertension associated with interstiti…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: iTONE Trial (exercIse Training in pulmONary hypertEnsion) Exercise Program for Pediatric PH [NA]
The iTONE trial, a pediatric exercise training program for pulmonary hypertension, is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Telerehabilitation in Patients With Elevated Pulmonary Artery Pressure [NA]
A telerehabilitation study is planned for patients with elevated pulmonary artery pressure. The trial status is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Feasibility of Semaglutide in Advanced Lung Disease [Phase 1, Phase 2]
Feasibility study of the GLP-1 agonist semaglutide for patients with obesity and advanced lung diseases, spanning Phase 1 and Phase 2, curre…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
This clinical trial registry entry describes the DeciPHer-ILD real-world patient registry focused on Group 3 pulmonary hypertension associat…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Evaluation of the BMPR2-Activin Signaling Pathway in Group II Pulmonary Hypertension.
A recruiting clinical trial at Hospital General Universitario Gregorio Marañon is evaluating the BMPR2-Activin signaling pathway in Group II…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Evolution of Hypoxic Burden and Sympathetic/Parasympathetic Balance in Patients With Pulmonary Hypertension [NA]
This clinical trial update indicates that the study on the evolution of hypoxic burden and autonomic balance in patients with precapillary p…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Right Ventricular Response to Exercise Among Patients With Chronic Obstructive Pulmonary Disease [NA]
This clinical trial update indicates recruitment for a study examining how exercise affects right ventricular function in patients with chro…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD) [Phase 3]
This clinical trial update indicates that Insmed's Treprostinil Palmitil Inhalation Powder (TPIP) is being studied in a Phase 3 trial for ef…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Natural History Study of Biomarkers in Pulmonary Arterial Hypertension
This entry describes a natural history study investigating biomarkers in pulmonary arterial hypertension, with recruitment currently ongoing…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option [Phase 3]
Phase 3 study offering treatment access to pulmonary hypertension patients who completed a parent trial and have no other option; the study …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Arterial Wave Energy Flux and Multidimensional Recovery in Patients With Chronic Thromboembolic Pulmonary Hypertension Undergoing Balloon Pulmonary Angioplasty
A recruiting clinical trial evaluating arterial wave energy flux and multidimensional recovery after balloon pulmonary angioplasty in patien…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Frespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With PH-COPD [Phase 2]
A Phase 2 clinical trial evaluating the efficacy and safety of inhaled Frespaciguat (MK-5475) in adults with pulmonary hypertension associat…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Observational Study of Patients Undergoing Diagnostic Right Heart Catheterization
An observational study evaluating patients undergoing diagnostic right heart catheterization is sponsored by HemoCept Inc., and is currently…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: TEPH: Telaglenastat Efficacy in Pulmonary Hypertension [Phase 1, Phase 2]
This clinical trial update describes planned evaluation of telaglenastat (CB-839) for efficacy in pulmonary hypertension in Phase 1/2, with …
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023) [Phase 2]
An extension-study trial update for sotatercept in people with pulmonary hypertension, currently in Phase 2 and recruiting (MK-7962-023).
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Real World Observational Study of Sotatercept for Pulmonary Hypertension
Real-world observational study assessing sotatercept for patients with pulmonary hypertension, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension [NA]
A multi-site clinical trial evaluates the clinical impact of an AI-assisted referral approach for diagnosing pulmonary hypertension in patie…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension [Phase 1]
Phase 1 Mayo Clinic study evaluating a bridge-to-lung transplant approach using trans-septal ECMO to support patients with right heart failu…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Insights Into Pediatric Pulmonary Hypertension: A Real-World Registry of Epidemiology and Outcomes
A real-world registry study focusing on pediatric pulmonary hypertension to investigate its epidemiology and patient outcomes.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants [NA]
A clinical trial update indicates a study investigating oxygen saturation targeting in preterm infants with bronchopulmonary dysplasia and p…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study) [Phase 2]
Phase 2 clinical trial APEX is evaluating TX000045 for pulmonary hypertension secondary to heart failure with preserved ejection fraction an…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Reverse Remodeling of the Pulmonary Vasculature: a Longitudinal, Investigational Study of the Effects of Sotatercept.
This clinical trial update outlines an investigational longitudinal study to evaluate reverse remodeling of the pulmonary vasculature with S…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Portosystemic Shunt-associated Pulmonary Hypertension Multi-center Prospective Cohort Study
This entry describes a multi-center prospective cohort study on portosystemic shunt–associated pulmonary hypertension, which is currently no…