Pulmonary Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-06Clinical Trial Results: Study of Ralinepag on Exercise Capacity by Cardiopulmonary Exercise Testing (CPET) in WHO Group 1 PH Subjects [Phase 3]
Phase 3 trial evaluating ralinepag on exercise capacity in pulmonary arterial hypertension; study terminated with posted results.
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EMA approval · 2026-06-09EMA Authorised: Winrevair (sotatercept) — Merck Sharp & Dohme B.V.
EMA authorised Winrevair (sotatercept) from Merck Sharp & Dohme B.V. for pulmonary hypertension and related hypertension therapeutic area.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Aerobic Exercise in Patients With Pulmonary Hypertension [Phase 2]
Phase 2 clinical trial update on aerobic exercise in patients with pulmonary hypertension (including interstitial lung disease) has complete…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD) [Phase 2, Phase 3]
Extension study update for Treprostinil Palmitil Inhalation Powder (TPIP) in pulmonary hypertension associated with interstitial lung diseas…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot
A pilot study update on NeoDoppler, a new ultrasound technology for continuous monitoring of cerebral circulation in neonates, currently rec…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Open-Label Rollover Study of Levosimendan in PH-HFpEF Patients [Phase 2]
The document reports the completion of an open-label Phase 2 rollover study evaluating levosimendan in patients with pulmonary hypertension …
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD [Phase 2]
Phase 2 clinical trial evaluating mosliciguat in combination with inhaled treprostinil for pulmonary hypertension associated with interstiti…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: iTONE Trial (exercIse Training in pulmONary hypertEnsion) Exercise Program for Pediatric PH [NA]
The iTONE trial, a pediatric exercise training program for pulmonary hypertension, is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Telerehabilitation in Patients With Elevated Pulmonary Artery Pressure [NA]
A telerehabilitation study is planned for patients with elevated pulmonary artery pressure. The trial status is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Infusion of Allogeneic Stromal Mesenchymal Stem Cells From Wharton´s Jelly in Patients With Diffuse Cutaneous Systemic Sclerosis With Refractory Pulmonary Involvement to Treatment [Phase 1, Phase 2]
The document reports the completion of a Phase 1/2 clinical trial evaluating intravenous infusion of allogeneic mesenchymal stem cells deriv…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Feasibility of Semaglutide in Advanced Lung Disease [Phase 1, Phase 2]
Feasibility study of the GLP-1 agonist semaglutide for patients with obesity and advanced lung diseases, spanning Phase 1 and Phase 2, curre…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
This clinical trial update notes the completion of a study investigating secondary pulmonary hypertension in adults with sickle cell disease…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
This clinical trial registry entry describes the DeciPHer-ILD real-world patient registry focused on Group 3 pulmonary hypertension associat…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Evaluation of the BMPR2-Activin Signaling Pathway in Group II Pulmonary Hypertension.
A recruiting clinical trial at Hospital General Universitario Gregorio Marañon is evaluating the BMPR2-Activin signaling pathway in Group II…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Study of Sotatercept for the Treatment of Cpc-PH Due to HFpEF (MK-7962-007/A011-16) [Phase 2]
Phase 2 clinical trial update for sotatercept in combined pre- and post-capillary pulmonary hypertension due to heart failure with preserved…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Evolution of Hypoxic Burden and Sympathetic/Parasympathetic Balance in Patients With Pulmonary Hypertension [NA]
This clinical trial update indicates that the study on the evolution of hypoxic burden and autonomic balance in patients with precapillary p…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients [Phase 3]
A Phase 3 trial evaluating Ralinepag for pulmonary arterial hypertension has completed; the update covers the study status and its efficacy …
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Right Ventricular Response to Exercise Among Patients With Chronic Obstructive Pulmonary Disease [NA]
This clinical trial update indicates recruitment for a study examining how exercise affects right ventricular function in patients with chro…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD) [Phase 3]
This clinical trial update indicates that Insmed's Treprostinil Palmitil Inhalation Powder (TPIP) is being studied in a Phase 3 trial for ef…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Natural History Study of Biomarkers in Pulmonary Arterial Hypertension
This entry describes a natural history study investigating biomarkers in pulmonary arterial hypertension, with recruitment currently ongoing…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option [Phase 3]
Phase 3 study offering treatment access to pulmonary hypertension patients who completed a parent trial and have no other option; the study …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Arterial Wave Energy Flux and Multidimensional Recovery in Patients With Chronic Thromboembolic Pulmonary Hypertension Undergoing Balloon Pulmonary Angioplasty
A recruiting clinical trial evaluating arterial wave energy flux and multidimensional recovery after balloon pulmonary angioplasty in patien…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Frespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With PH-COPD [Phase 2]
A Phase 2 clinical trial evaluating the efficacy and safety of inhaled Frespaciguat (MK-5475) in adults with pulmonary hypertension associat…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Observational Study of Patients Undergoing Diagnostic Right Heart Catheterization
An observational study evaluating patients undergoing diagnostic right heart catheterization is sponsored by HemoCept Inc., and is currently…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: TEPH: Telaglenastat Efficacy in Pulmonary Hypertension [Phase 1, Phase 2]
This clinical trial update describes planned evaluation of telaglenastat (CB-839) for efficacy in pulmonary hypertension in Phase 1/2, with …