Pulmonary Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-02-26Clinical Trial Update: Targeting Right Ventricle in Pulmonary Hypertension Gilead [Phase 4]
Phase 4 trial summary posted for a pulmonary hypertension study targeting the right ventricle, completed with results available in 2019.
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: Riociguat Clinical Effects Studied in Patients With Insufficient Treatment Response to Phosphodiesterase-5 Inhibitor [Phase 3]
Riociguat was studied in a Phase 3 clinical trial for patients with pulmonary hypertension who had insufficient response to PDE-5 inhibitors…
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CLINICAL_TRIALS trial_result · 2019-02-05Clinical Trial Update: 11C-acetate/18Fluorodeoxyglucose-FDG PET/CT and Cardiac MRI in Pulmonary Hypertension [Phase 2]
Phase 2 clinical trial update reporting results from imaging studies using 11C-acetate and 18F-FDG PET/CT plus cardiac MRI in patients with …
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CLINICAL_TRIALS trial_result · 2019-01-22Clinical Trial Update: A Phase 1 Relative Bioavailability Study of Ambrisentan and Tadalfil Fixed Dose Combination Tablets in Healthy Subjects [Phase 1]
This Phase 1 study evaluated the relative bioavailability of a fixed-dose combination tablet of ambrisentan and tadalafil in healthy subject…
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CLINICAL_TRIALS trial_result · 2019-01-09Clinical Trial Update: Sildenafil in Hemodialysis Patients With Pulmonary Hypertension [Phase 2, Phase 3]
Phase 2/3 trial evaluating sildenafil in patients on hemodialysis with pulmonary hypertension; status not specified.
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CLINICAL_TRIALS trial_result · 2018-12-19Clinical Trial Update: Targeting the Right Ventricle in Pulmonary Hypertension [Phase 4]
Phase 4 clinical trial update reporting completed results on therapies aimed at improving right-ventricular function in pulmonary hypertensi…
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CLINICAL_TRIALS trial_result · 2018-11-07Clinical Trial Update: Natrecor in Pulmonary Hypertension [Phase 4]
Phase 4 clinical trial update for Natrecor in pulmonary hypertension; study terminated.
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CLINICAL_TRIALS trial_result · 2018-10-31Clinical Trial Update: A Multiple Dose Titration Study of MK-8892 in Participants With Pulmonary Hypertension and Left Heart Disease (MK-8892-007) [Phase 1]
Phase 1 multiple-dose titration study of MK-8892 in participants with pulmonary hypertension and left heart disease was terminated; results …
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CLINICAL_TRIALS trial_result · 2018-10-24Clinical Trial Update: The Role of Endothelin in Pulmonary Hypertension [Phase 2]
Phase 2 clinical trial update examining the role of endothelin in pulmonary hypertension has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-08-27Clinical Trial Update: L-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary Hypertension [Phase 4]
Phase 4 trial comparing L-arginine to sildenafil in children with beta thalassemia and pulmonary hypertension.
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CLINICAL_TRIALS trial_result · 2018-08-02Clinical Trial Update: Ambrisentan (Letairis) for Sarcoidosis Associated Pulmonary Hypertension [Phase 2, Phase 3]
Clinical trial update on ambrisentan (Letairis) for sarcoidosis-associated pulmonary hypertension; study phases 2 and 3 completed.
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: Phase 2 Study of Ex-vivo Perfusion and Ventilation of Lungs to Assess Transplant Suitability [NA]
Phase 2 trial evaluating ex-vivo lung perfusion and ventilation to assess transplant suitability, sponsored by the University of North Carol…
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CLINICAL_TRIALS trial_result · 2018-07-11Clinical Trial Update: The Exercise Capacity and Quality of Life in the Patients With IPAH and Secondary PH
A completed clinical trial evaluating exercise capacity and quality of life in patients with idiopathic pulmonary arterial hypertension and …
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CLINICAL_TRIALS trial_result · 2018-07-09Clinical Trial Update: Study of the Efficacy and Safety of Tezosentan in Patients With Pre-operative Pulmonary Hypertension, Due to Left Heart Disease, Undergoing Open Heart Surgery [Phase 3]
A Phase 3 study evaluating the efficacy and safety of tezosentan in patients with pre-operative pulmonary hypertension due to left heart dis…
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Effect of Nasal Highflow on Right Heart Function [NA]
A completed clinical trial by the University of Leipzig evaluated the effect of nasal high-flow therapy on right heart function in patients …
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: PDEI Following Mitral Valve Surgery in Patients With Pulmonary Hypertension [Phase 4]
Phase 4 clinical trial evaluating a phosphodiesterase inhibitor in patients with pulmonary hypertension undergoing mitral valve surgery has …
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CLINICAL_TRIALS trial_result · 2018-05-07Clinical Trial Update: Sildenafil Versus Placebo in Chronic Heart Failure [Phase 3]
This update reports a Phase 3 trial comparing sildenafil to placebo in patients with heart failure (with associated pulmonary hypertension) …
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability [NA]
This completed clinical trial evaluated ex-vivo perfusion and ventilation of donor lungs recovered from non-heart-beating donors to assess t…
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CLINICAL_TRIALS trial_result · 2018-03-01Clinical Trial Update: Inspiratory Muscle Training in Pulmonary Hypertension [NA]
A completed clinical trial evaluating inspiratory muscle training in patients with pulmonary hypertension.
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CLINICAL_TRIALS trial_result · 2018-02-13Clinical Trial Update: Efficacy of Beraprost in Lowering Pulmonary Arterial Pressure in Children [Phase 4]
Phase 4 trial update on beraprost showing efficacy in lowering pulmonary arterial pressure in pediatric pulmonary hypertension.
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CLINICAL_TRIALS trial_result · 2017-12-07Clinical Trial Update: Inhaled Iloprost (Ventavis): Efficacy, Safety, and Pharmacokinetics (PK) Confirmation Study [Phase 3]
Phase 3 confirmation study of inhaled iloprost (Ventavis) evaluating efficacy, safety, and pharmacokinetics has completed.
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CLINICAL_TRIALS trial_result · 2017-11-30Clinical Trial Update: PAHTCH Pulmonary Arterial Hypertension Treatment With Carvedilol for Heart Failure (Carvedilol) [NA]
A completed clinical trial evaluating carvedilol for pulmonary arterial hypertension in heart failure; results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-11-27Clinical Trial Update: Safety and Efficacy Study of HGP1207 in Patients With Pulmonary Hypertension [Phase 3]
Phase 3 clinical trial update assessing the safety and efficacy of HGP1207 in patients with pulmonary hypertension.
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CLINICAL_TRIALS trial_result · 2017-10-23Clinical Trial Update: Angioplasty of Distal Lesions for Carriers of Inoperable Post-embolic HTP [NA]
This entry reports completion of a clinical trial evaluating angioplasty of distal lesions in patients with inoperable post-embolic pulmonar…
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CLINICAL_TRIALS trial_result · 2017-09-26Clinical Trial Update: Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure [Phase 3]
Phase 3 trial evaluating inhaled nitric oxide for severe respiratory failure in preterm infants; study terminated.