Pulmonary Hypertension
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: Inhaled Treprostinil in Participants With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD) [Phase 3]
Phase 3 trial of inhaled treprostinil for pulmonary hypertension due to chronic obstructive pulmonary disease was terminated, with results p…
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CLINICAL_TRIALS trial_result · 2023-11-24Clinical Trial Update: A Phase 3 Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Participants With Pulmonary Hypertension (PH) Due to Chronic Obstructive Pulmonary Disease (COPD) [Phase 3]
A Phase 3 adaptive trial evaluating inhaled treprostinil for pulmonary hypertension due to COPD was terminated; results were posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-11-08Clinical Trial Update: Piloting Mindfulness Meditation Program for Underserved Racial Minority Adults With Pulmonary Hypertension [NA]
Completed clinical trial piloting a mindfulness meditation program for underserved racial minority adults with pulmonary hypertension; resul…
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CLINICAL_TRIALS trial_result · 2023-10-24Clinical Trial Update: A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH [Phase 3]
Phase 3 trial evaluating ralinepag effects on exercise capacity in pulmonary arterial hypertension (PAH) was terminated.
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CLINICAL_TRIALS trial_result · 2023-10-12Clinical Trial Update: Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER [Phase 3]
This clinical trial update reports termination of an extended access program evaluating the long-term safety of bardoxolone methyl in patien…
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CLINICAL_TRIALS trial_result · 2023-10-05Clinical Trial Update: Qutenza®-Remodulin® in Pulmonary Arterial Hypertension Patients [Phase 2]
Phase 2 clinical trial update for Qutenza®-Remodulin® in pulmonary arterial hypertension and pain conditions.
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: A Study to Evaluate the Efficacy, Safety and Tolerability of PDNO Infusion in Patients With Pulmonary Hypertension After Cardiopulmonary Bypass Surgery [Phase 2]
Phase 2 clinical trial evaluating PDNO infusion for efficacy, safety, and tolerability in pulmonary hypertension following cardiopulmonary b…
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: A Study to Assess Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Fibrosis at Risk for Pulmonary Hypertension [Phase 3]
Phase 3 trial of pulsed inhaled nitric oxide in subjects with pulmonary fibrosis at risk for pulmonary hypertension was terminated.
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CLINICAL_TRIALS trial_result · 2023-02-28Clinical Trial Update: The Right Ventricular Pulmonary Circulation Continuum in Mitral Valve Disease Study
A completed clinical trial studying the right ventricular-pulmonary circulation continuum in patients with mitral valve disease, including m…
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CLINICAL_TRIALS trial_result · 2023-02-28Clinical Trial Update: A Study to Assess Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Hypertension Associated With Pulmonary Fibrosis [Phase 2]
Phase 2 clinical trial evaluating pulsed inhaled nitric oxide for pulmonary hypertension associated with pulmonary fibrosis (pulmonary fibro…
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CLINICAL_TRIALS trial_result · 2023-02-27Clinical Trial Update: Inhaled Nitric Oxide/INOpulse DS for Pulmonary Arterial Hypertension (PAH) [Phase 2]
Phase 2 clinical trial update for inhaled nitric oxide (INOpulse DS) in pulmonary arterial hypertension (PAH) has completed enrollment/statu…
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CLINICAL_TRIALS trial_result · 2023-02-27Clinical Trial Update: Two-Part Dose-Confirming Study of Pulsed Inhaled Nitric Oxide in Subjects With WHO Group 3 Pulmonary Hypertension Associated With COPD [Phase 2]
Phase 2 trial update on pulsed inhaled nitric oxide for WHO Group 3 pulmonary hypertension associated with COPD has been completed.
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CLINICAL_TRIALS trial_result · 2022-12-02Clinical Trial Update: An Open Label Extension Study to Evaluate Inhaled Treprostinil in Adult PH With ILD Including CPFE [Phase 2, Phase 3]
Open-label extension study assessing inhaled treprostinil in adults with pulmonary hypertension associated with interstitial lung disease, i…
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CLINICAL_TRIALS trial_result · 2022-08-10Clinical Trial Update: A Dose Escalation Study to Assess the Safety and Efficacy of Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Fibrosis or Sarcoidosis [Phase 2]
Phase 2 dose-escalation trial evaluating pulsed inhaled nitric oxide for safety and efficacy in pulmonary fibrosis and sarcoidosis (complete…
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CLINICAL_TRIALS trial_result · 2022-02-10Clinical Trial Update: Improving Treatment Personalization of Pulmonary Hypertension Associated With Diastolic Heart Failure [Phase 4]
A Phase 4 trial on personalizing treatment for pulmonary hypertension associated with diastolic heart failure was terminated; results were p…
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CLINICAL_TRIALS trial_result · 2022-02-09Clinical Trial Update: Study of Dehydroepiandrosterone (DHEA) in Respiratory Pulmonary Hypertension in Adults [Phase 2]
Phase 2 trial evaluating dehydroepiandrosterone (DHEA) for pulmonary hypertension in adults with chronic obstructive pulmonary disease (COPD…
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CLINICAL_TRIALS trial_result · 2021-12-02Clinical Trial Update: Ketones for Pulmonary Hypertension - Effects on Hemodynamics [Phase 2]
Phase 2 trial update on ketones for pulmonary hypertension assessing effects on hemodynamics; study completed.
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CLINICAL_TRIALS trial_result · 2021-10-25Clinical Trial Update: Enteral L Citrulline Supplementation in Preterm Infants - Safety, Efficacy and Dosing [Phase 1]
Phase 1 trial evaluating safety, efficacy, and dosing of enteral L-citrulline supplementation in preterm infants with bronchopulmonary dyspl…
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CLINICAL_TRIALS trial_result · 2021-09-28Clinical Trial Update: Treatment of PH With Angiotensin II Receptor Blocker and Neprilysin Inhibitor in HFpEF Patients With CardioMEMS Device [Phase 3]
Phase 3 trial evaluating angiotensin receptor blocker and neprilysin inhibitor therapy for pulmonary hypertension in patients with a CardioM…
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CLINICAL_TRIALS trial_result · 2021-08-30Clinical Trial Update: Effect of Inhaled Albuterol in Pulmonary Hypertension [Phase 2]
Phase 2 trial evaluating inhaled albuterol for pulmonary hypertension has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-07-23Clinical Trial Update: Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT [Phase 2]
A Phase 2 clinical trial (LARIAT) evaluating Bardoxolone Methyl in patients with pulmonary hypertension has completed and results have been …
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CLINICAL_TRIALS trial_result · 2021-07-13Clinical Trial Update: Safety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFE [Phase 2, Phase 3]
Phase 2/3 trial evaluating inhaled treprostinil for pulmonary hypertension associated with interstitial lung disease, including combined pul…
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CLINICAL_TRIALS trial_result · 2021-06-10Clinical Trial Update: Glutamine Therapy for Hemolysis-Associated Pulmonary Hypertension [Phase 2]
Phase 2 clinical trial evaluating glutamine therapy for hemolysis-associated pulmonary hypertension in patients with sickle cell disease. St…
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CLINICAL_TRIALS trial_result · 2021-04-01Clinical Trial Update: Clinical Study to Assess the Efficacy and Safety of Macitentan in Patients With Pulmonary Hypertension After Left Ventricular Assist Device Implantation [Phase 2]
This update reports results from a Phase 2 study evaluating Macitentan for efficacy and safety in patients with pulmonary hypertension after…
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CLINICAL_TRIALS trial_result · 2021-03-09Clinical Trial Update: Tadalafil for Pulmonary Hypertension Due to Chronic Lung Disease [Phase 2]
Phase 2 trial evaluating tadalafil for pulmonary hypertension due to chronic lung disease (COPD) has completed; results posted in 2021.