Primitive Neuroectodermal Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors
An exploratory study evaluating the effects of radiation therapy in pediatric patients with central nervous system tumors; the study include…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Rare CNS Tumors Outcomes &Risk
A National Cancer Institute clinical trial update reports outcomes and risks for rare central nervous system tumors, including meningioma, e…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors [Phase 1]
Phase 1 trial evaluating locoregional HER2-targeted CAR T-cell therapy for pediatric recurrent or refractory central nervous system tumors a…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors [Phase 1]
Phase 1 trial evaluating locoregional EGFR806-specific CAR T cells for EGFR-positive pediatric CNS tumors. The study status is completed.
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CLINICAL_TRIALS withdrawal · 2024-10-26Clinical Trial Update: Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer [Phase 1]
A Phase 1 trial investigating chemotherapy and donor stem cell transplantation for high-grade brain cancers has been withdrawn. The study in…
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CLINICAL_TRIALS trial_result · 2022-02-07Clinical Trial Update: Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor [Phase 2]
Phase 2 clinical trial of a vaccine immunotherapy for recurrent medulloblastoma and primitive neuroectodermal tumor has completed and result…
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CLINICAL_TRIALS trial_result · 2022-01-11Clinical Trial Update: Concurrent Carboplatin and Reduced Dose Craniospinal Radiation for Medulloblastoma and Primitive Neuroectodermal Tumor (PNET) [Phase 2]
Phase 2 trial evaluating concurrent carboplatin with reduced-dose craniospinal irradiation for metatstic medulloblastoma and high-risk supra…
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CLINICAL_TRIALS trial_result · 2021-10-29Clinical Trial Update: Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of Chemotherapy [Phase 2]
Phase 2 trial of Zalypsis (PM00104) in unresectable or metastatic Ewing family tumors progressed after prior chemotherapy; study completed w…
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CLINICAL_TRIALS trial_result · 2021-10-26Clinical Trial Update: Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating melphalan, carboplatin, mannitol, and sodium thiosulfate for recurrent or progressive central nervous sy…
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CLINICAL_TRIALS trial_result · 2019-09-13Clinical Trial Update: Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors [Phase 2]
Phase 2 trial evaluating temozolomide and irinotecan with or without bevacizumab in young patients with recurrent or refractory medulloblast…
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children [Phase 2, Phase 3]
This document is an update on a Phase 2/Phase 3 therapy optimization trial for relapsed or refractory pediatric brain tumors, which has comp…
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: 18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcoma [EARLY_Phase 1]
Early-phase clinical trial evaluating 18F-FLT PET and diffusion-weighted MRI to plan surgery and radiation therapy and measure response in n…
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CLINICAL_TRIALS trial_result · 2016-10-27Clinical Trial Update: QUILT-3.025: A Phase 2 Study of AMG 479 in Relapsed or Refractory Ewing's Family Tumor and Desmoplastic Small Round Cell Tumors [Phase 2]
Phase 2 results for AMG 479 in relapsed or refractory Ewing sarcoma family tumors, including Askin's tumor and desmoplastic small round cell…
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CLINICAL_TRIALS trial_result · 2014-07-28Clinical Trial Update: Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Primitive Neuroectodermal Tumors [Phase 2]
A Phase 2 trial by the Children's Oncology Group evaluated radiation therapy, chemotherapy, and peripheral stem cell transplantation for pri…
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CLINICAL_TRIALS trial_result · 2013-09-30Clinical Trial Update: Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors [Phase 1]
This Phase 1 trial evaluates the combination of temozolomide and O6-benzylguanine in pediatric patients with recurrent brain tumors.
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CLINICAL_TRIALS other · 2013-09-20Clinical Trial Update: Quality of Life in Patients Who Have Undergone Previous Treatment for Primitive Neuroectodermal Tumors
This clinical trial update discusses quality-of-life outcomes in patients who have previously received treatment for primitive neuroectoderm…
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CLINICAL_TRIALS trial_result · 2013-08-09Clinical Trial Update: Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor [Phase 3]
Phase 3 trial evaluating combination chemotherapy followed by second-look surgery and radiation for untreated childhood medulloblastoma or s…
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CLINICAL_TRIALS trial_result · 2013-08-02Clinical Trial Update: Combination Chemotherapy, Surgery or Radiation Therapy, and Peripheral Stem Cell Transplant in Treating Patients With Recurrent Medulloblastoma or Primitive Neuroectodermal and Pineal Tumors [Phase 2]
A Phase 2 trial evaluating combination chemotherapy, surgery or radiation therapy, and peripheral stem cell transplantation for patients wit…
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CLINICAL_TRIALS trial_result · 2013-07-18Clinical Trial Update: Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma [Phase 2]
Phase 2 study of combination chemotherapy followed by radiation therapy in children with medulloblastoma, supratentorial primitive neuroecto…
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CLINICAL_TRIALS trial_result · 2013-06-05Clinical Trial Update: Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors [Phase 1]
Phase 1 study evaluating the combination of erlotinib and temozolomide in pediatric patients with recurrent or refractory solid tumors has c…
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CLINICAL_TRIALS trial_result · 2013-02-18Clinical Trial Update: Combination Chemotherapy in Treating Children With Astrocytomas and Primitive Neuroectodermal Tumors [Phase 2]
A Phase 2 clinical trial evaluated combination chemotherapy for children with astrocytomas and primitive neuroectodermal tumors; the study s…
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CLINICAL_TRIALS trial_result · 2013-02-01Clinical Trial Update: Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Ewing's Sarcoma or Primitive Neuroectodermal Tumor [Phase 2]
The document reports results from a Phase 2 clinical trial evaluating combination chemotherapy in newly diagnosed metastatic Ewing sarcoma o…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia [Phase 1]
Phase 1 trial evaluating FR901228 in pediatric patients with refractory or recurrent solid tumors or leukemia has completed.
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CLINICAL_TRIALS trial_result · 2012-09-24Clinical Trial Update: Chemotherapy in Treating Patients With Metastatic Ewing's Sarcoma or Primitive Neuroectodermal Tumor [Phase 2]
Phase 2 chemotherapy trial for metastatic Ewing's sarcoma or primitive neuroectodermal tumor has been terminated.
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CLINICAL_TRIALS trial_result · 2012-05-16Clinical Trial Update: Exatecan Mesylate in Treating Patients With Ewing's Sarcoma, Primitive Neuroectodermal Tumor, or Desmoplastic Small Round Cell Tumor [Phase 2]
Phase 2 trial of exatecan mesylate for Ewing's sarcoma, primitive neuroectodermal tumor, and desmoplastic small round cell tumor has complet…