Plexiform Neurofibroma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors [Phase 1, Phase 2]
The National Cancer Institute reports a Phase 1/Phase 2 trial of selumetinib (AZD6244 hydrogen sulfate) for children with neurofibromatosis …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway. [Phase 2]
Phase 2 clinical trial evaluating trametinib in pediatric neuro-oncology patients with refractory tumors showing MAPK/ERK pathway activation…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ... [Phase 1]
Phase I trial of pexidartinib (TURALIO) in children and young adults with refractory leukemias and solid tumors including NF1-associated ple…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Evaluation of TQ-B3234 Capsules in Patients With Symptomatic, Non-Surgical Type 1 Neurofibromatosis-Associated Plexiform Neurofibromas [Phase 3]
A Phase 3 clinical trial evaluating TQ-B3234 capsules for symptomatic, non-surgical type 1 neurofibromatosis-associated plexiform neurofibro…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Real-World Treatment Study of Koselugo (Selumetinib)
AstraZeneca is conducting a real-world study of Koselugo (selumetinib) that is currently recruiting for neurofibromatosis type 1 and plexifo…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Natural History Study of Patients With Neurofibromatosis Type I
The National Cancer Institute is conducting an observational natural history study of patients with Neurofibromatosis Type 1. The study is c…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1 [Phase 2]
A Phase 2 clinical trial is evaluating selumetinib (Koselugo) to prevent plexiform neurofibroma growth in Neurofibromatosis type 1; the stud…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: A Study of Avutometinib for People With Solid Tumor Cancers [Phase 1]
A Phase 1 study of Avutometinib for people with solid tumors, including CNS tumors and NF1-associated tumors, is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Observational Study to Evaluate the Effect and Safety of Selumetinib in Pediatric Patients With NF1-PNs
An update on an observational study evaluating the effect and safety of selumetinib in pediatric patients with NF1-associated plexiform neur…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: A Study of Selumetinib in Chinese Paediatric and Adult Subjects With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN) [Phase 1]
A Phase 1 study of selumetinib in Chinese pediatric and adult subjects with Neurofibromatosis Type 1 and inoperable plexiform neurofibromas …
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Neurofibromatosis Type 1 Tumor Early Detection Study
This clinical trial update announces a study for early detection of tumors in Neurofibromatosis Type 1, and the study is currently recruitin…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: PAS-004 in Adults Who Have Neurofibromatosis Type 1 With Plexiform Neurofibromas [Phase 1]
Phase 1 clinical trial evaluating PAS-004 in adults with Neurofibromatosis Type 1 and related plexiform neurofibromas; currently recruiting.
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Follow-up Study to Evaluate the Safety and Efficacy of FCN-159 in Pediatric Participants With Neurofibromatosis Type 1 [Phase 1, Phase 2]
A registry update describing a Phase 1/Phase 2 follow-up study evaluating FCN-159 in pediatric patients with Neurofibromatosis Type 1, focus…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: FCN-159 in Adult Patients With Symptomatic, Inoperable Neurofibromatosis Type 1-Related Plexiform Neurofibromas [Phase 3]
A Phase 3 clinical trial update on FCN-159 for symptomatic, inoperable Neurofibromatosis type 1-related plexiform neurofibromas, sponsored b…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1 [Phase 1, Phase 2]
This Phase 1/2 clinical trial evaluates FCN-159 in adults and children with Neurofibromatosis type 1 and plexiform neurofibroma to assess sa…