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CLINICAL_TRIALS ClinicalTrials.gov record update

A Phase 1/1b Open Label Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PAS-004, a MAPK/ERK Kinase 1/2 (MEK 1/2) Inhibitor, in Adult Participants With Neurofibromatosis Type 1 (NF1) With Symptomatic and Inoperable, Incompletely Resected, or Recurrent Plexiform Neurofibromas

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Record identity and dates

Source
ClinicalTrials.gov
Source record ID
NCT06961565
Title field or adapter rule
protocolSection.identificationModule.officialTitle
Ingested At
2026-04-25T22:28:53.308074+00:00
Published At
2025-12-04T00:00:00+00:00
Record Updated At
2025-12-04
Timestamp Basis
source retrieval time was not retained by the feed adapter
Date limitation
source retrieval time was not retained by the feed adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions
["NF1 Mutation", "Neurofibroma Plexiform", "Neurofibroma, Plexiform", "Neurofibromatosis Type 1 (NF1)-Related Plexiform Neurofibromas (PNs)", "Neurofibromatosis Type 1 (NF1)"]
protocolSection.statusModule.lastUpdatePostDateStruct.date
"2025-12-04"
protocolSection.identificationModule.nctId
"NCT06961565"
protocolSection.identificationModule.officialTitle
"A Phase 1/1b Open Label Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PAS-004, a MAPK/ERK Kinase 1/2 (MEK 1/2) Inhibitor, in Adult Participants With Neurofibromatosis Type 1 (NF1) With Symptomatic and Inoperable, Incompletely Resected, or Recurrent Plexiform Neurofibromas"
protocolSection.statusModule.overallStatus
"RECRUITING"
protocolSection.designModule.phases
["PHASE1"]
protocolSection.statusModule.resultsFirstPostDateStruct.date
""

Study condition terms

  • NF1 Mutation (protocolSection.conditionsModule.conditions)
  • Neurofibroma Plexiform (protocolSection.conditionsModule.conditions)
  • Neurofibroma, Plexiform (protocolSection.conditionsModule.conditions)
  • Neurofibromatosis Type 1 (NF1)-Related Plexiform Neurofibromas (PNs) (protocolSection.conditionsModule.conditions)
  • Neurofibromatosis Type 1 (NF1) (protocolSection.conditionsModule.conditions)

Intervention details are not present in the imported fields for this record. No drug-condition relationship is inferred from co-listing.

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