Patent Ductus Arteriosus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-04-06Clinical Trial Update: Platelet Transfusion for Treatment of Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates [Phase 3]
A Phase 3 trial evaluating platelet transfusion as a treatment for patent ductus arteriosus in thrombocytopenic preterm neonates has complet…
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CLINICAL_TRIALS trial_result · 2018-03-23Clinical Trial Update: NIT-OCCLUD PDA Phase II Sentinel Trial [NA]
A Phase II sentinel trial evaluating the NIT-OCCLUD PDA device for closing patent ductus arteriosus has completed.
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Increase of Prostaglandin E2 in Reversal of Ductal Constriction After Dietary Restriction of Polyphenols [NA]
This clinical trial update notes the completion of a study investigating whether dietary restriction of polyphenols increases prostaglandin …
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CLINICAL_TRIALS trial_result · 2016-09-09Clinical Trial Update: A New Device for Measuring of Lung Photoplethysmography and Pulmonic Arterial Saturation
A clinical trial update describing a new device to measure lung photoplethysmography and pulmonic arterial saturation, in the context of Pat…
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CLINICAL_TRIALS trial_result · 2016-09-07Clinical Trial Update: Plethismographic Perfusion Index in Neonates
Clinical trial update on Plethismographic Perfusion Index in neonates, involving patent ductus arteriosus and persistent pulmonary hypertens…
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CLINICAL_TRIALS trial_result · 2016-08-18Clinical Trial Update: An Escalating Dose Indomethacin for the Treatment of Persistent Patent Ductus Arteriosus (PDA) In Preterm Infants [Phase 2, Phase 3]
The document describes escalating-dose indomethacin trials for treating persistent patent ductus arteriosus in preterm infants, across Phase…
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CLINICAL_TRIALS trial_result · 2016-07-06Clinical Trial Update: Paracetamol Treatment of the Borderline Significant PDA [Phase 2]
An update on a Phase 2 clinical trial evaluating paracetamol for the treatment of patent ductus arteriosus.
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CLINICAL_TRIALS trial_result · 2016-07-04Clinical Trial Update: Early Versus Late Use of Ibuprofen for Patent Ductus Arteriosus (PDA) Closure [NA]
This clinical trial update reports the results of a terminated study comparing early versus late use of ibuprofen to close patent ductus art…
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CLINICAL_TRIALS trial_result · 2016-04-26Clinical Trial Update: The Impact of Platelet Functions on Spontaneous Ductal Closure in Preterm Infants
A completed Ankara University–sponsored study examined how platelet function relates to spontaneous closure of the ductus arteriosus in pret…
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CLINICAL_TRIALS trial_result · 2016-04-06Clinical Trial Update: Influence of Treatment for Patent Ductus Arteriosus on Cerebral Oxygenation in Preterm Infants
A completed clinical trial evaluated how treatment of patent ductus arteriosus influences cerebral oxygenation in preterm infants.
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Reproduction and Survival After Cardiac Defect Repair
The NHLBI-sponsored clinical trial reports on reproduction and survival outcomes after repair of congenital heart defects; the study has com…
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Safety of Fluconazole Treatment of Premature and Full-term Newborn Infants [Phase 4]
Phase 4 safety update evaluating fluconazole treatment in premature and full-term newborn infants.
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CLINICAL_TRIALS trial_result · 2015-06-26Clinical Trial Update: The Pharmacology and Hemodynamics of Dexmedetomidine in Children With Congenital Heart Disease [Phase 3]
Phase 3 clinical trial update evaluating the pharmacology and hemodynamics of dexmedetomidine in children with congenital heart disease, wit…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP) [Phase 3]
Phase 3 trial of Indomethacin prophylaxis in preterm, very low birth weight infants (TIPP) has completed, evaluating prevention of patent du…
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CLINICAL_TRIALS trial_result · 2014-12-05Clinical Trial Update: Timing for the Medical Treatment of Patent Ductus Arteriosus in Preterm Infants
A completed clinical trial from the University of Utah examines when to start medical treatment for patent ductus arteriosus in preterm infa…
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CLINICAL_TRIALS trial_result · 2014-07-18Clinical Trial Update: Closure Of Patent Ductus Arteriosus With the AMPLATZER Duct Occluder the AMPLATZER® Duct Occluder [NA]
A completed clinical trial evaluating the AMPLATZER Duct Occluder for closing patent ductus arteriosus (PDA) has posted results.
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CLINICAL_TRIALS trial_result · 2014-04-11Clinical Trial Update: Pocket Echocardiography System (PES) for Detection of PDA in Neonates [NA]
This update reports the completion and posting of results for a clinical trial evaluating a Pocket Echocardiography System to detect Patent …
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CLINICAL_TRIALS trial_result · 2014-01-28Clinical Trial Update: Safety/Efficacy Study of Optimizing Ibuprofen Dosing to Achieve Higher PDA Closure Rates [Phase 4]
A Phase 4 safety/efficacy trial evaluating optimized ibuprofen dosing for higher patent ductus arteriosus closure rates was TERMINATED.
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CLINICAL_TRIALS trial_result · 2014-01-03Clinical Trial Update: Patent Ductus Arteriosus (PDA) Screening Trial [NA]
The patent ductus arteriosus (PDA) screening trial has completed, with no results reported in the update.
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CLINICAL_TRIALS trial_result · 2013-12-16Clinical Trial Update: AMPLATZER Duct Occluder II Clinical Study [NA]
Clinical study of the AMPLATZER Duct Occluder II in patients with Patent Ductus Arteriosus; the trial is completed with results posted on 20…
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CLINICAL_TRIALS trial_result · 2013-12-13Clinical Trial Update: Management of Patent Ductus in Premature Infants [Phase 3]
Phase 3 clinical trial evaluating management of patent ductus arteriosus in premature infants has completed.
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CLINICAL_TRIALS trial_result · 2013-11-28Clinical Trial Update: Timing of PDA Closure and Respiratory Outcome in Premature Infants [NA]
A clinical trial evaluated the timing of patent ductus arteriosus closure and its effect on respiratory outcomes in premature infants. The s…
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CLINICAL_TRIALS trial_result · 2013-08-28Clinical Trial Update: Long Term Results of 450 Percutaneous Closures of PDA in a Single Center
This clinical trial report presents long-term outcomes of 450 percutaneous closures of patent ductus arteriosus performed at a single center…
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CLINICAL_TRIALS trial_result · 2013-07-04Clinical Trial Update: Do Elevated BNP Levels Predict Hemodynamically Significant PDAs
A completed clinical trial evaluating whether elevated BNP levels can predict hemodynamically significant patent ductus arteriosus.
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CLINICAL_TRIALS trial_result · 2013-01-03Clinical Trial Update: Closure of Patent Ductus Arteriosus With Indomethacin or Ibuprofen in Extreme Low Birth Weight Infants [NA]
This clinical trial evaluating indomethacin or ibuprofen for closing patent ductus arteriosus in extremely low birth weight infants has comp…