Osteosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-10-31Clinical Trial Update: Liposomal Vincristine for Pediatric and Adolescent Patients With Relapsed Malignancies [Phase 2]
Phase 2 trial evaluating liposomal vincristine in pediatric and adolescent patients with relapsed malignancies has completed.
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CLINICAL_TRIALS trial_result · 2018-10-15Clinical Trial Update: Glembatumumab Vedotin in Treating Patients With Recurrent or Refractory Osteosarcoma [Phase 2]
Phase 2 trial evaluating Glembatumumab Vedotin in recurrent or refractory osteosarcoma has completed with posted results.
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CLINICAL_TRIALS trial_result · 2018-09-26Clinical Trial Update: A Clinical Study of PD-L1 Antibody ZKAB001(Drug Code) in Limited Stage of High-grade Osteosarcoma [Phase 1, Phase 2]
Clinical trial update for ZKAB001 (PD-L1 antibody) in limited stage high-grade osteosarcoma, across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2018-09-19Clinical Trial Update: Cryoablation, Radiofrequency Ablation, or Microwave Ablation in Treating Patients With Metastatic Sarcoma Stable on Chemotherapy [Phase 2]
Phase 2 trial evaluating cryoablation, radiofrequency ablation, or microwave ablation for metastatic sarcoma stable on chemotherapy; study t…
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CLINICAL_TRIALS trial_result · 2018-09-18Clinical Trial Update: Haploidentical Stem Cell Transplantation and NK Cell Therapy in Patients With High-risk Solid Tumors [Phase 2]
Phase 2 clinical trial evaluating haploidentical stem cell transplantation with NK cell therapy in high-risk solid tumors, including neurobl…
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FDA approval · 2018-07-27FDA Approved: LEUCOVORIN CALCIUM — Original Application (Fresenius Kabi USA, LLC)
FDA approved a generic Leucovorin Calcium under ANDA 207226 for Fresenius Kabi USA, LLC.
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CLINICAL_TRIALS trial_result · 2018-06-29Clinical Trial Update: Monocyte Phenotypic and Functional Differences
The Duke University-led study 'Monocyte Phenotypic and Functional Differences' (NCT02132182) has completed, examining monocyte characteristi…
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: Apatinib for Advanced Osteosarcoma After Failure of Standard Multimodal Therapy [Phase 2, Phase 3]
Phase 2/3 trial evaluating Apatinib in advanced osteosarcoma after failure of standard multimodal therapy; the study has completed.
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CLINICAL_TRIALS trial_result · 2018-03-21Clinical Trial Update: HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors [Phase 1]
This update reports the completion of a Phase 1 clinical trial evaluating HSV-1716 in patients with non-CNS solid tumors, including rhabdomy…
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FDA approval · 2018-03-15FDA Approved: METHOTREXATE — Supplemental Application (Hospira, Inc.)
FDA approved a supplemental application for Methotrexate submitted by Hospira, Inc.
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CLINICAL_TRIALS trial_result · 2018-01-09Clinical Trial Update: Feasibility Study of Interval Compressed Regimen Using Four-drugs for Osteosarcoma [Phase 2]
Phase 2 feasibility trial update evaluating a four-drug interval-compressed regimen for osteosarcoma.
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CLINICAL_TRIALS research · 2017-12-05Clinical Trial Update: The Osteosarcoma Biobank in Peking University People's Hospital
This entry notes the Osteosarcoma Biobank study at Peking University People's Hospital, focusing on osteosarcoma; the current status is unkn…
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CLINICAL_TRIALS research · 2017-11-30Clinical Trial Update: Patient-derived Xenograft (PDX) Modeling to Test Drug Response for High-grade Osteosarcoma
The document outlines a clinical trial update on using patient-derived xenograft models to test drug response in high-grade osteosarcoma to …
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CLINICAL_TRIALS withdrawal · 2017-11-24Clinical Trial Update: A Vaccine Study for High Risk Cancers [Phase 1]
A Phase 1 cancer vaccine study has been withdrawn; it targeted neuroblastoma, rhabdomyosarcoma, and osteosarcoma.
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CLINICAL_TRIALS research · 2017-11-13Clinical Trial Update: Epigenetic Biomarker for Osteosarcoma
This clinical trial update reports on an epigenetic biomarker study in osteosarcoma. It examines endpoints including histologic response, ob…
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CLINICAL_TRIALS trial_result · 2017-11-01Clinical Trial Update: A Phase II of Nivolumab Plus Ipilimumab in Non-resectable Sarcoma and Endometrial Carcinoma [Phase 2]
Phase II trial of nivolumab plus ipilimumab in non-resectable soft tissue and bone sarcomas, with exploration across several sarcoma subtype…
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CLINICAL_TRIALS trial_result · 2017-09-01Clinical Trial Update: Eribulin Mesylate in Treating Patients With Recurrent or Refractory Osteosarcoma [Phase 2]
Phase 2 clinical trial assessing eribulin mesylate in patients with recurrent or refractory osteosarcoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-08-17Clinical Trial Update: A Phase I Trial Of The Humanized Anti-GD2 Antibody In Children And Adolescents With Neuroblastoma, Osteosarcoma, Ewing Sarcoma and Melanoma [Phase 1]
A Phase I trial of a humanized anti-GD2 antibody in children and adolescents with neuroblastoma, osteosarcoma, Ewing sarcoma, and melanoma h…
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CLINICAL_TRIALS trial_result · 2017-08-01Clinical Trial Update: Inhalation SLIT Cisplatin (Liposomal) for the Treatment of Osteosarcoma Metastatic to the Lung [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating inhaled liposomal cisplatin for metastatic osteosarcoma to the lung has been completed with resu…
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CLINICAL_TRIALS guidance · 2017-07-02Clinical Trial Update: Informed Consent in Pediatric Cancer Trials
NCI provides guidance on informed consent practices for pediatric cancer clinical trials, highlighting considerations to protect children an…
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CLINICAL_TRIALS withdrawal · 2017-07-02Clinical Trial Update: RO4929097 in Children With Relapsed/Refractory Solid or CNS Tumors, Lymphoma, or T-Cell Leukemia [Phase 1]
Phase 1 trial of RO4929097 in children with relapsed/refractory solid or CNS tumors, lymphoma, or T-cell leukemia has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-07-02Clinical Trial Update: A Phase I Study of Pazopanib as a Single Agent for Children With Refractory Solid Tumors [Phase 1]
A Phase I study of pazopanib as a single agent for children with refractory solid tumors has been withdrawn from the trial program.
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia [Phase 2]
Phase 2 clinical trial update evaluating alisertib in pediatric patients with various recurrent or refractory solid tumors and leukemia; stu…
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CLINICAL_TRIALS research · 2017-05-23Clinical Trial Update: Apatinib Second Line Treatment for Advanced Osteosarcoma and Soft Tissue Sarcomas ,Openting ,Single Center, One-armed Clinical Study. [Phase 2]
A Phase 2, single-arm trial evaluating apatinib as second-line therapy for advanced osteosarcoma and soft tissue sarcomas; the status is cur…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Decitabine Followed by a Cancer Antigen Vaccine for Patients With Neuroblastoma and Sarcoma [Phase 1]
A Phase 1 trial evaluating decitabine followed by a cancer antigen vaccine in neuroblastoma and various sarcomas has completed.