Osteosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-10-29Clinical Trial Update: Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer [Phase 3]
Phase 3 trial comparing fixed versus flexible dosing of filgrastim to speed bone marrow recovery after chemotherapy in children; the study i…
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FDA approval · 2020-10-13FDA Approved: LEUCOVORIN CALCIUM — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental application for Leucovorin Calcium by Hikma Pharmaceuticals USA Inc., resulting in updated labeling for the gene…
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CLINICAL_TRIALS trial_result · 2020-09-17Clinical Trial Update: Study of Lenvatinib in Children and Adolescents With Refractory or Relapsed Solid Malignancies and Young Adults With Osteosarcoma [Phase 1, Phase 2]
Phase 1/2 trial of lenvatinib in pediatric/adolescent and young adult patients with refractory or relapsed solid malignancies and osteosarco…
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CLINICAL_TRIALS trial_result · 2020-09-04Clinical Trial Update: Cabozantinib S-malate in Treating Patients With Relapsed Osteosarcoma or Ewing Sarcoma [Phase 2]
Phase 2 clinical trial update evaluating Cabozantinib S-malate in patients with relapsed or unresectable metastatic osteosarcoma or Ewing sa…
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CLINICAL_TRIALS trial_result · 2020-08-10Clinical Trial Update: Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas [Phase 2]
Phase 2 trial evaluating pazopanib hydrochloride combined with topotecan hydrochloride in adults with metastatic or recurrent soft tissue an…
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CLINICAL_TRIALS trial_result · 2020-05-19Clinical Trial Update: Apatinib Plus Anti-PD1 Therapy for Advanced Osteosarcoma [Phase 2]
Phase 2 trial update evaluating apatinib plus anti-PD1 therapy in advanced osteosarcoma has completed, reporting measures such as progressio…
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CLINICAL_TRIALS trial_result · 2020-05-19Clinical Trial Update: Comparison of MAPI+Camrelizumab Versus API+Apatinib Versus MAPI in Patients With a Poor Response to Preoperative Chemotherapy for Newly Diagnosed High-grade Osteosarcoma [Phase 2]
Phase 2 trial comparing MAPI+camrelizumab, API+apatinib, and MAPI monotherapy in patients with poor response to preoperative chemotherapy fo…
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CLINICAL_TRIALS trial_result · 2020-04-29Clinical Trial Update: Study of ZKAB001 for Maintenance Therapy in Patients With High-grade Osteosarcoma After Adjuvant Chemotherapy [Phase 3]
A Phase 3 clinical trial evaluating ZKAB001 as maintenance therapy after adjuvant chemotherapy in patients with high-grade osteosarcoma.
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CLINICAL_TRIALS trial_result · 2020-03-30Clinical Trial Update: Phase II Clinical Trial Scheme of Ganoderma Lucidum Spore Powder for Postoperative Chemotherapy of Osteosarcoma [Phase 2]
Phase II trial update for Ganoderma Lucidum Spore Powder as postoperative chemotherapy for osteosarcoma (Phase 2).
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CLINICAL_TRIALS trial_result · 2020-03-16Clinical Trial Update: Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy [Phase 2]
Phase 2 trial updating strategies to prevent nephrotoxicity and ototoxicity in osteosarcoma therapy; results posted after completion.
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CLINICAL_TRIALS trial_result · 2020-03-04Clinical Trial Update: Study of Camrelizumab in Combination With Neoadjuvant Chemotherapy in the Treatment of Osteosarcoma [Phase 2]
Phase 2 clinical trial evaluating camrelizumab in combination with neoadjuvant chemotherapy for osteosarcoma.
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FDA approval · 2020-01-30FDA Approved: METHOTREXATE — Original Application (Chartwell RX, LLC)
FDA approvedChartwell RX, LLC's methotrexate product under an Original Application, making a new generic version of methotrexate available. …
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: A Placebo-Controlled Study of Saracatinib (AZD0530) in Patients With Recurrent Osteosarcoma Localized to the Lung [Phase 2]
Phase 2 placebo-controlled trial of saracatinib in patients with recurrent osteosarcoma localized to the lung was terminated; results posted…
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CLINICAL_TRIALS trial_result · 2020-01-10Clinical Trial Update: Therapy Trial to Determine the Safety and Efficacy of Heavy Ion Radiotherapy in Patients With Osteosarcoma [Phase 1, Phase 2]
A clinical trial update reports on safety and efficacy of heavy ion radiotherapy for osteosarcoma in Phase 1/2, completed.
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: Co-treatment With GnRH Analogs on the Ovarian Reserve in Young Women Treated With Alkylating Agents for Cancer [Phase 2, Phase 3]
A Phase 2/Phase 3 trial evaluating co-treatment with GnRH analogs to protect ovarian reserve in young women receiving alkylating chemotherap…
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CLINICAL_TRIALS trial_result · 2019-10-29Clinical Trial Update: Combination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk Osteosarcoma [Phase 2]
Phase 2 trial evaluating external beam radiotherapy with 153Sm-EDTMP for metastatic osteosarcoma; the study is terminated with results poste…
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CLINICAL_TRIALS trial_result · 2019-09-13Clinical Trial Update: A Eurosarc Study of Mifamurtide in Advanced Osteosarcoma (MEMOS) [Phase 2]
Phase 2 MEMOS trial evaluating mifamurtide in advanced osteosarcoma has been terminated with results posted.
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FDA approval · 2019-08-22FDA Approved: LEVOLEUCOVORIN — Original Application (Meitheal Pharmaceuticals Inc)
FDA approved Meitheal Pharmaceuticals' levoleucovorin calcium as an original application (ANDA) for a generic product.
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CLINICAL_TRIALS trial_result · 2019-08-07Clinical Trial Update: Phase 2 Study of Inhaled Lipid Cisplatin in Pulmonary Recurrent Osteosarcoma [Phase 2]
Phase 2 trial update for inhaled lipid cisplatin in pulmonary relapse osteosarcoma has completed.
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CLINICAL_TRIALS trial_result · 2019-06-26Clinical Trial Update: Investigation of [6R] 5,10-methylenetetrahydrofolate (Arfolitixorin) as Rescue Therapy for Osteosarcoma Patients Treated With HDMTX. [Phase 1, Phase 2]
Phase 1/2 trial investigating Arfolitixorin as rescue therapy for osteosarcoma patients receiving high-dose methotrexate; study completed wi…
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CLINICAL_TRIALS trial_result · 2019-06-18Clinical Trial Update: Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI [Phase 2]
Phase 2 clinical trial updating the use of ferumoxytol-enhanced MRI to differentiate bone sarcomas from osteomyelitis.
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CLINICAL_TRIALS trial_result · 2019-05-17Clinical Trial Update: Adjuvant High-Dose Thiotepa and Stem Cell Rescue Associated With Conventional Chemotherapy in Relapsed Osteosarcoma [Phase 2]
Phase 2 trial investigating adjuvant high-dose thiotepa with stem cell rescue alongside conventional chemotherapy in relapsed osteosarcoma h…
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CLINICAL_TRIALS trial_result · 2019-05-06Clinical Trial Update: Zoledronic Acid in Decrease the Lung Metastatic Rate of Osteosarcoma [Phase 4]
Phase 4 trial evaluating whether zoledronic acid reduces lung metastases in osteosarcoma.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Localized Osteosarcoma in Upper Egypt: A Clinical Prediction Model
A completed study from Assiut University evaluating a clinical prediction model for localized osteosarcoma.
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CLINICAL_TRIALS trial_result · 2019-01-29Clinical Trial Update: Activated T Cells Armed With GD2 Bispecific Antibody in Children and Young Adults With Neuroblastoma and Osteosarcoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating activated T cells armed with a GD2 bispecific antibody to treat disseminated or recurrent neuroblastoma …