Osteosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: DFMO Maintenance for Patients With Relapsed/Refractory Ewing Sarcoma or Osteosarcoma [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating maintenance therapy with DFMO for relapsed or refractory Ewing sarcoma and osteosarcoma is curre…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Collecting and Storing Tissue From Young Patients With Cancer
A completed clinical trial update from the Children’s Oncology Group describing the collection and storage of tissue from pediatric cancer p…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors [Phase 1]
Phase 1 trial evaluating autologous B7-H3 CAR T cells in relapsed/refractory solid tumors, including neuroblastoma, sarcoma, and osteosarcom…
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone Tumors
A recruiting study examining tissue expression of Krüppel-like factors 4 and 7 in pediatric bone tumors, including osteosarcoma and Ewing sa…
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: A Look Back at How Well Interventional Treatments Work for Bronchopleural Fistulas in Patients With Lung Metastases From Osteosarcoma
The entry reviews interventional treatments for bronchopleural fistulas in patients with lung metastases from osteosarcoma; the study is cur…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Study to Assess Safety and Efficacy of Vactosertib in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the safety and efficacy of Vactosertib in adolescents and adults with recurrent, refractory, or progre…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Quality of Life of Patients With Bone Tumor of the Lower Limbs Treated With Salvage Surgery
This completed clinical trial evaluates quality of life in patients with lower-limb bone tumors treated with salvage surgery.
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Phase 2 STIR Trial: Haploidentical Transplant and Donor Natural Killer Cells for Solid Tumors [Phase 2]
Phase 2 trial update of haploidentical transplantation with donor natural killer cells for solid tumors; the study was terminated and result…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO) [NA]
This entry reports on the MICCHADO trial, which investigates the biological characterization of high-risk childhood cancers. The sponsor is …
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Exploring the Expression Level of Cadherin 6 Protein (CDH6) in Primary Malignant Bone Tumor Specimens and Its Clinical Application in Prognosis Assessment
This clinical trial assesses the expression of Cadherin 6 (CDH6) in primary malignant bone tumors and investigates its potential use for pro…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: Anti-GD2 CAR T Cells in Pediatric Patients Affected by High Risk and/or Relapsed/Refractory Neuroblastoma or Other GD2-positive Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating Anti-GD2 CAR T cells in pediatric patients with high-risk or relapsed/refractory neuroblastoma and other…
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CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: Precision Therapy Based on Immune Microenvironment by Transcriptome Sequencing of Osteosarcoma, a Prospective, Multi-cohort Exploratory Clinical Study
A prospective exploratory clinical study using transcriptome sequencing to guide precision therapy for osteosarcoma, with the trial status n…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Osteosarcoma Maintenance Therapy With OST31-164 [Phase 2]
Phase 2 clinical trial evaluating OST31-164 as maintenance therapy for osteosarcoma (bone cancer); sponsored by Emerald Clinical Inc. The st…
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: B7-H3 NIR Imaging for Osteosarcoma Surgery [Phase 1, Phase 2]
Clinical trial update for a B7-H3-targeted near-infrared imaging probe to assist osteosarcoma surgery, spanning Phase 1 and Phase 2 and curr…
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CLINICAL_TRIALS withdrawal · 2025-01-15Clinical Trial Update: Natalizumab in Recurrent, Refractory or Progressive Pulmonary Metastatic Osteosarcoma [Phase 1, Phase 2]
The Phase 1/Phase 2 trial of natalizumab for pulmonary metastatic osteosarcoma has been withdrawn.
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: A Phase 2 Pilot Study to Evaluate the Safety and the Anti-Tumour Activity of the Myc Inhibitor OMO-103 Administered Intravenously in Patients With Advanced High-Grade Osteosarcoma [Phase 2]
Phase 2 pilot study evaluating the safety and anti-tumor activity of the Myc inhibitor OMO-103 given intravenously in patients with advanced…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors [Phase 2]
Phase 2 trial evaluating neoadjuvant dual checkpoint inhibition with cryoablation in relapsed/refractory pediatric solid tumors has complete…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors [Phase 1]
Phase 1 trial completion evaluating MR-guided High Intensity Focused Ultrasound (HIFU) for relapsed or refractory pediatric solid tumors, in…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: Quantitative Margin Assessment Using High-resolution Positron Emission Tomography - Computed Tomograhy [NA]
A University Medical Center Groningen clinical trial is evaluating quantitative margin assessment using high-resolution PET-CT in oral squam…
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: Trilaciclib Combing Chemotherapy in the Neoadjuvant Treatment of Osteosarcoma [Phase 2]
This is a status update on a Phase 2 trial evaluating trilaciclib with chemotherapy for osteosarcoma, currently recruiting.
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: ARTEMIS-103: Phase 1b Study of HS-20093 Combinations in Patients with Bone and Soft Tissue Sarcoma. [Phase 1]
A Phase 1b trial (ARTEMIS-103) evaluates HS-20093 in patients with bone and soft tissue sarcoma, and the study is currently not recruiting.
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CLINICAL_TRIALS withdrawal · 2024-11-08Clinical Trial Update: BIO-11006 for Osteosarcoma and Ewing's Sarcoma Lung Metastases [Phase 2]
A Phase 2 study of BIO-11006 for metastatic osteosarcoma and metastatic Ewing's sarcoma with lung metastases has been withdrawn.
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FDA approval · 2024-10-23FDA Approved: JYLAMVO — Supplemental Application (SHORLA ONCOLOGY INC.)
The FDA approved a supplemental application for JYLAMVO (methotrexate) filed by SHORLA ONCOLOGY INC.
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CLINICAL_TRIALS research · 2024-09-25Clinical Trial Update: Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton Therapy [NA]
This clinical trial update outlines a study comparing daily 1-beam versus 2-beam proton therapy to assess toxicity and efficacy in chordoma,…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 update on erdafitinib for FGFR-mutant relapsed or refractory pediatric cancers enrolled in the Pediatric MATCH trial; results were p…