Osteosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas [Phase 1]
Phase 1 dose-escalation study of CLR-131 in children with relapsed or refractory malignant tumors, including neuroblastoma and sarcomas, cur…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Apatinib Combined With Liposomal Irinotecan for Refractory or Metastatic Osteosarcoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating apatinib in combination with liposomal irinotecan for refractory or metastatic osteosarcoma; the st…
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CLINICAL_TRIALS other · 2026-03-18Clinical Trial Update: Expanded Access Use of L-MTP-PE for the Treatment of Osteosarcoma
The document reports expanded access use of L-MTP-PE (mifamurtide) for osteosarcoma, providing patients outside of a formal trial with acces…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma [Phase 2]
Phase 2 clinical trial evaluating the combination of gefitinib, trametinib, disulfiram, and sunitinib with standard chemotherapy for osteosa…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Upfront Surgical Resection for Osteosarcoma
An ongoing clinical study at Montefiore Medical Center is evaluating upfront surgical resection for osteosarcoma and is currently recruiting…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: BLESSED: Expanded Access for DNG64-CAR-V for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of Breast
Expanded access (compassionate use) for the DNG64-CAR-V cell therapy in patients with advanced pancreatic cancer, various sarcoma subtypes, …
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma [Phase 1, Phase 2]
A phase 1/2 study evaluating CAR.70-engineered IL-15-transduced cord blood-derived NK cells with lymphodepleting chemotherapy for advanced r…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Liposomal Irinotecan, Vincristine, Temozolomide, and Anlotinib for R/R Pediatric Solid Tumors [Phase 2]
This clinical trial update outlines a Phase 2 study evaluating a combination of liposomal irinotecan, vincristine, temozolomide, and anlotin…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery for Relapsed Osteosarcoma [Phase 1]
Phase 1 clinical trial evaluating atezolizumab in combination with SBRT and surgery for relapsed osteosarcoma (including pulmonary recurrenc…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Tegavivint With Gemcitabine in Patients With Relapsed or Refractory Osteosarcoma [Phase 1]
A Phase 1 trial of tegavivint with gemcitabine in relapsed or refractory osteosarcoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma [Phase 3]
This Phase 3 clinical trial assesses thoracotomy versus thoracoscopic management of pulmonary metastases in patients with osteosarcoma and i…
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: Olaparib With Ceralasertib in Recurrent Osteosarcoma [Phase 2]
Phase 2 trial evaluating the combination of olaparib and ceralasertib in recurrent osteosarcoma; the study is currently active but not recru…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the safety and potential efficacy of PEEL-224 in combination with vincristine and temozolomide in a…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas [NA]
Investigates regorafenib as maintenance therapy after first-line treatment in patients with bone sarcomas and related subtypes. The trial is…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas Patients [Phase 2]
This clinical trial update notes ongoing Phase 2 evaluation of regorafenib plus best supportive care as maintenance therapy for high-grade b…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Genetically Engineered Cells (FH-FOLR1 ST CAR T Cells) for the Treatment of Advanced Refractory or Recurrent/Progressive Osteosarcoma, FIERCe Trial [Phase 1]
A Phase 1 study investigating FH-FOLR1 ST CAR T cells for advanced, refractory, or recurrent osteosarcoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Iscador® P (Mistletoe) Immunotherapy for Recurrent Osteogenic Sarcoma [Phase 2]
This Phase 2 clinical trial is evaluating Iscador P (mistletoe) immunotherapy for recurrent osteosarcoma and the study is currently recruiti…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas [Phase 1]
Phase 1 clinical trial in pediatric relapsed/refractory sarcomas evaluating hypofractionated radiation in combination with B7-H3-CAR T cells…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Lu-TARGO (177Lu-TARGeted Osteosarcoma Therapy) [Phase 1, Phase 2]
The document notes that Lu-TARGO (177Lu-TARGeted Osteosarcoma Therapy) is currently recruiting Phase 1/2 trials for relapsed or refractory o…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: SPEARHEAD-3 Pediatric Study [Phase 1, Phase 2]
SPEARHEAD-3 is a pediatric study enrolling in Phase 1 and Phase 2 across multiple cancers, including synovial sarcoma, malignant peripheral …
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Pediatric PET/MR Image Registry
A pediatric PET/MR image registry is currently recruiting to collect imaging data for soft tissue sarcoma, lymphoma, and osteosarcoma.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or Neuroblastoma [Phase 1]
Phase 1 trial evaluating NKG2D.Zeta-NK cell conditioning combined with C7R.GD2.CAR-T cells in patients with relapsed or refractory neuroblas…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative Planning [NA]
A clinical study sponsored by Ricoh USA, Inc. is evaluating the use of 3D-printed models to assist pre-operative planning for various sarcom…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable Osteosarcoma [Phase 1]
Phase 1 clinical trial evaluating nivolumab alone or with azacitidine in patients with recurrent, resectable osteosarcoma. The study is curr…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Long Term Brain Toxicity of Chemotherapy in Patients Treated for a Bone TumorDuring Childhood or Adolescence [NA]
This clinical trial update describes long-term brain toxicity from chemotherapy in adults who were treated for osteosarcoma or Ewing sarcoma…