Osteosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors [Phase 1]
Phase 1 trial evaluating autologous B7-H3 CAR T cells in relapsed/refractory solid tumors, including neuroblastoma, sarcoma, and osteosarcom…
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone Tumors
A recruiting study examining tissue expression of Krüppel-like factors 4 and 7 in pediatric bone tumors, including osteosarcoma and Ewing sa…
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: A Look Back at How Well Interventional Treatments Work for Bronchopleural Fistulas in Patients With Lung Metastases From Osteosarcoma
The entry reviews interventional treatments for bronchopleural fistulas in patients with lung metastases from osteosarcoma; the study is cur…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Study to Assess Safety and Efficacy of Vactosertib in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the safety and efficacy of Vactosertib in adolescents and adults with recurrent, refractory, or progre…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO) [NA]
This entry reports on the MICCHADO trial, which investigates the biological characterization of high-risk childhood cancers. The sponsor is …
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Exploring the Expression Level of Cadherin 6 Protein (CDH6) in Primary Malignant Bone Tumor Specimens and Its Clinical Application in Prognosis Assessment
This clinical trial assesses the expression of Cadherin 6 (CDH6) in primary malignant bone tumors and investigates its potential use for pro…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: Anti-GD2 CAR T Cells in Pediatric Patients Affected by High Risk and/or Relapsed/Refractory Neuroblastoma or Other GD2-positive Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating Anti-GD2 CAR T cells in pediatric patients with high-risk or relapsed/refractory neuroblastoma and other…
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CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: Precision Therapy Based on Immune Microenvironment by Transcriptome Sequencing of Osteosarcoma, a Prospective, Multi-cohort Exploratory Clinical Study
A prospective exploratory clinical study using transcriptome sequencing to guide precision therapy for osteosarcoma, with the trial status n…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Osteosarcoma Maintenance Therapy With OST31-164 [Phase 2]
Phase 2 clinical trial evaluating OST31-164 as maintenance therapy for osteosarcoma (bone cancer); sponsored by Emerald Clinical Inc. The st…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: A Phase 2 Pilot Study to Evaluate the Safety and the Anti-Tumour Activity of the Myc Inhibitor OMO-103 Administered Intravenously in Patients With Advanced High-Grade Osteosarcoma [Phase 2]
Phase 2 pilot study evaluating the safety and anti-tumor activity of the Myc inhibitor OMO-103 given intravenously in patients with advanced…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: Quantitative Margin Assessment Using High-resolution Positron Emission Tomography - Computed Tomograhy [NA]
A University Medical Center Groningen clinical trial is evaluating quantitative margin assessment using high-resolution PET-CT in oral squam…
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: Trilaciclib Combing Chemotherapy in the Neoadjuvant Treatment of Osteosarcoma [Phase 2]
This is a status update on a Phase 2 trial evaluating trilaciclib with chemotherapy for osteosarcoma, currently recruiting.
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: ARTEMIS-103: Phase 1b Study of HS-20093 Combinations in Patients with Bone and Soft Tissue Sarcoma. [Phase 1]
A Phase 1b trial (ARTEMIS-103) evaluates HS-20093 in patients with bone and soft tissue sarcoma, and the study is currently not recruiting.
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CLINICAL_TRIALS research · 2024-09-25Clinical Trial Update: Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton Therapy [NA]
This clinical trial update outlines a study comparing daily 1-beam versus 2-beam proton therapy to assess toxicity and efficacy in chordoma,…
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CLINICAL_TRIALS research · 2024-08-23Clinical Trial Update: ARTEMIS-002: HS-20093 in Patients With Relapsed or Refractory Osteosarcoma and Other Sarcomas [Phase 2]
Phase 2 study ARTEMIS-002 (HS-20093) is evaluating HS-20093 in patients with relapsed or refractory osteosarcoma and other sarcomas; the tri…
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: Safety and Feasibility of Intraoperative Visualization With Cytalux in Children [Phase 1]
Phase 1 safety and feasibility trial evaluating intraoperative visualization with Cytalux (pafolacianine) in children with osteosarcoma and …
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Single High-dose Brachytherapy for Giant Osteosarcoma Masses [Phase 2]
Phase 2 clinical trial update on single high-dose brachytherapy for giant osteosarcoma masses; the study status is not yet recruiting.
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: ICONIC: Improving Outcomes Through Collaboration in OsteosarComa
University College London is leading an ongoing clinical trial called ICONIC (Improving Outcomes Through Collaboration in Osteosarcoma), cur…
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Soluble B7-H3 as a Biomarker for Osteosarcoma
This study investigates soluble B7-H3 as a biomarker for osteosarcoma progression. It is currently recruiting and sponsored by Peking Univer…
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CLINICAL_TRIALS research · 2017-12-05Clinical Trial Update: The Osteosarcoma Biobank in Peking University People's Hospital
This entry notes the Osteosarcoma Biobank study at Peking University People's Hospital, focusing on osteosarcoma; the current status is unkn…
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CLINICAL_TRIALS research · 2017-11-30Clinical Trial Update: Patient-derived Xenograft (PDX) Modeling to Test Drug Response for High-grade Osteosarcoma
The document outlines a clinical trial update on using patient-derived xenograft models to test drug response in high-grade osteosarcoma to …
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CLINICAL_TRIALS research · 2017-11-13Clinical Trial Update: Epigenetic Biomarker for Osteosarcoma
This clinical trial update reports on an epigenetic biomarker study in osteosarcoma. It examines endpoints including histologic response, ob…
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CLINICAL_TRIALS research · 2017-05-23Clinical Trial Update: Apatinib Second Line Treatment for Advanced Osteosarcoma and Soft Tissue Sarcomas ,Openting ,Single Center, One-armed Clinical Study. [Phase 2]
A Phase 2, single-arm trial evaluating apatinib as second-line therapy for advanced osteosarcoma and soft tissue sarcomas; the status is cur…
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CLINICAL_TRIALS research · 2016-11-01Clinical Trial Update: Clinical Trial of Lithium Carbonate Combined With Neo-adjuvant Chemotherapy to Treat Osteosarcoma [Phase 4]
A Phase 4 clinical trial evaluating lithium carbonate in combination with neo-adjuvant chemotherapy for osteosarcoma; current status is not …
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CLINICAL_TRIALS research · 2016-05-19Clinical Trial Update: Study of Blood Samples From Patients With Osteosarcoma
A completed study sponsored by the Children's Oncology Group analyzes blood samples from patients with osteosarcoma to study biomarkers.