Osteosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas [Phase 2]
Phase 2 study of LN-145 (LN-145-S1) in relapsed or refractory ovarian cancer, triple-negative breast cancer, anaplastic thyroid cancer, oste…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
Phase 1 clinical trial update describing B7H3-targeted CAR T-cell therapy for recurrent/refractory pediatric solid tumors, including several…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
A Phase 1 trial update for EGFR806 CAR T cell immunotherapy in pediatric and young adult patients with recurrent/refractory solid tumors; th…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: A Phase I Feasibility And Safety Study of Fluorescein-Specific (FITC-E2) CAR T Cells In Combination With Parenterally Administered Folate-Fluorescein (UB-TT170) For Osteogenic Sarcoma [Phase 1]
Phase I feasibility and safety study of fluorescein-specific (FITC-E2) CAR T cells in combination with Folate-Fluorescein (UB-TT170) for ost…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas [Phase 1]
A Phase 1 trial evaluating the combination of cabozantinib with ifosfamide in relapsed/refractory sarcomas is currently recruiting at Childr…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: SARC038: Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma [Phase 2]
This ClinicalTrials.gov update describes a Phase 2 study testing regorafenib in combination with nivolumab for osteosarcoma, including pedia…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors [Phase 1]
Phase 1 pediatric trial evaluating alpha/beta CD19+ depleted haploidentical transplantation in combination with Zoledronic acid (Zometa) for…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Machine Learning Applied to EHRs Data of Patients With Sarcoma
Completed study from the University of Milano Bicocca applying machine learning to electronic health records of patients with sarcoma (inclu…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Humanized Monoclonal Antibody 3F8 (Hu3F8) With Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) in the Treatment of Recurrent Osteosarcoma [Phase 2]
This clinical trial update describes a Phase 2 study of Hu3F8 (humanized anti-GD2 monoclonal antibody) in combination with GM-CSF for recurr…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Tumor Microenvironment in Patients With Localized Osteosarcoma Treated With Mifamurtide: a Translational Study
This translational study investigates how mifamurtide affects the tumor microenvironment in patients with localized osteosarcoma.
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: An Observational Study of Local Relapse After High Grade Osteosarcoma
An observational study assessing local relapse after high-grade osteosarcoma, currently recruiting, sponsored by Istituto Ortopedico Rizzoli…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: AOH1996 for the Treatment of Refractory Solid Tumors [Phase 1]
AOH1996 is being studied in a Phase 1 trial for patients with refractory solid tumors, including osteosarcoma and several other sarcomas and…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: A Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone Sarcomas [Phase 2]
Phase II clinical trial evaluating regorafenib for metastatic bone sarcomas is active but not recruiting, including Ewing sarcoma, chondrosa…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors. [NA]
This clinical trial update describes a post-treatment program to identify and manage complications related to oncology or hematology treatme…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Chemotherapy Resistance in Osteogenic Sarcoma and Other Solid Tumors [NA]
Clinical trial update from Memorial Sloan Kettering Cancer Center on chemotherapy resistance in osteosarcoma and other solid tumors, with th…
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Envafolimab Combined With Neoadjuvant Chemotherapy Treat Stage IIb Resectable Osteosarcoma Patients [Phase 2]
A Phase 2 trial update reports testing Envafolimab in combination with neoadjuvant chemotherapy for stage IIb resectable osteosarcoma, with …
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Descriptive Cohort of French Patients Treated With Carbonetherapy Since October 2010 Outside PHRC-ETOILE
Describes a descriptive cohort of French patients treated with carbon ion therapy for various cancers, reported outside a PHRC-ETOILE progra…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Clinical Orthopaedic Data Bank (Acute and Chronic)
ClinicalTrials.gov update indicates the Clinical Orthopaedic Data Bank study on acute and chronic conditions is currently recruiting. The li…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N) [Phase 1]
ClinicalTrials.gov entry updates the Phase 1 study of C7R-GD2.CART cells for relapsed or refractory GD2-positive cancers, including neurobla…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration [Phase 2]
A Phase 2 clinical trial evaluating abemaciclib for bone and soft tissue sarcomas with CDK pathway alterations is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Safety and Efficacy of DIT309 in Advanced Bone and Soft Tissue Sarcomas [Phase 1]
This document reports a Phase 1 clinical trial evaluating the safety and efficacy of DIT309 in advanced bone and soft tissue sarcomas, with …
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
An ongoing clinical trial is evaluating whether dexrazoxane hydrochloride affects biomarkers linked to cardiomyopathy and heart failure afte…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Early Ageing During Therapy in AYA Cancer Patients
A clinical trial investigating early ageing during therapy in adolescents and young adults with cancer is currently recruiting. The study co…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: DFMO Maintenance for Patients With Relapsed/Refractory Ewing Sarcoma or Osteosarcoma [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating maintenance therapy with DFMO for relapsed or refractory Ewing sarcoma and osteosarcoma is curre…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Collecting and Storing Tissue From Young Patients With Cancer
A completed clinical trial update from the Children’s Oncology Group describing the collection and storage of tissue from pediatric cancer p…