Osteogenesis Imperfecta
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Evaluation and Treatment of Patients With Connective Tissue Disease
This clinical trial update reports on the evaluation and treatment of patients with connective tissue disorders, including osteogenesis impe…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Evaluation and Intervention for the Effects of Osteogenesis Imperfecta
A NICHD-sponsored clinical trial evaluating interventions for the effects of osteogenesis imperfecta has completed.
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Study to Evaluate Efficacy and Safety of Romosozumab Compared With Bisphosphonates in Children and Adolescents With Osteogenesis Imperfecta [Phase 3]
A Phase 3 clinical trial evaluating the efficacy and safety of romosozumab compared with bisphosphonates in children and adolescents with os…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Setrusumab in Pediatric Japanese Subjects With Osteogenesis Imperfecta [Phase 3]
A Phase 3 clinical trial of setrusumab in pediatric Japanese patients with Osteogenesis Imperfecta is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: Natural History of the Collagen-Related Disorder Osteogenesis Imperfecta and Genotype Phenotype Correlation
This completed clinical trial documents the natural history of Osteogenesis Imperfecta and investigates genotype-phenotype correlations. The…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: Post-market Observational Study on JTIN Telescopic Nail in Osteogenesis Imperfecta Pediatric Patients
A post-market observational study of the JTIN Telescopic Nail in pediatric patients with Osteogenesis Imperfecta has completed and results h…
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: Treatment of Osteogenesis Imperfecta With Parathyroid Hormone and Zoledronic Acid [Phase 4]
A Phase 4 trial evaluating parathyroid hormone and zoledronic acid for osteogenesis imperfecta has completed.
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Single Ascending Dose Study of SAR439459 in Adults With Osteogenesis Imperfecta (OI) [Phase 1]
A Phase 1 single ascending dose study of SAR439459 in adults with Osteogenesis Imperfecta has been terminated.
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Evaluation of the Benefits of Adaptive Physical Activity in Children and Adolescents With Osteogenesis Imperfecta [NA]
A completed clinical trial evaluating the benefits of adaptive physical activity for children and adolescents with osteogenesis imperfecta.
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Epigenetic Regulation of Osteogenesis Imperfecta Severity : miROI Study [NA]
The miROI study investigating epigenetic regulation of Osteogenesis Imperfecta severity has completed.
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: Long-term Extension Study of Setrusumab in Adults With Type I, III, or IV Osteogenesis Imperfecta [Phase 2]
Long-term extension phase 2 study of Setrusumab in adults with Osteogenesis Imperfecta (types I, III, IV) was terminated, and results were p…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Osteogenesis Imperfecta Blood Pressure Study
A clinical trial investigating blood pressure in Osteogenesis Imperfecta has completed.
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Ready to Sail: Evaluating Sailing's Feasibility as Ergotherapy [NA]
A completed clinical trial from Istituto Ortopedico Rizzoli evaluated sailing as ergotherapy for patients with Multiple Osteochondroma, Olli…
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: A First-in-Human Study Evaluating AGA2115 in Adult Healthy Volunteers [Phase 1]
A first-in-human Phase 1 trial evaluating AGA2115 in adult healthy volunteers has completed, investigating safety and pharmacology in relati…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Safety of Fresolimumab in the Treatment of Osteogenesis Imperfecta [Phase 1]
Phase 1 safety study of Fresolimumab in Osteogenesis Imperfecta has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-08-16Clinical Trial Update: e-Health Care Method for Patients With Osteogenesis Imperfecta (Tele OI) [NA]
This clinical trial update indicates completion of a study evaluating an e-health care method (Tele OI) for patients with Osteogenesis Imper…
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CLINICAL_TRIALS trial_result · 2024-04-15Clinical Trial Update: Study to Evaluate Romosozumab in Children and Adolescents With Osteogenesis Imperfecta [Phase 1]
Phase 1 study evaluating romosozumab in children and adolescents with Osteogenesis Imperfecta has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-12-28Clinical Trial Update: Multicenter,Single-arm Study to Evaluate Efficacy, Safety, & Pharmacokinetics of Denosumab in Children w/ OI [Phase 3]
Phase 3 multicenter single-arm trial evaluating denosumab in children with osteogenesis imperfecta; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2022-12-20Clinical Trial Update: Open-label Extension of Study 20130173 of Denosumab in Children and Young Adults With Osteogenesis Imperfecta [Phase 3]
Open-label extension of a Phase 3 trial evaluating denosumab in children and young adults with osteogenesis imperfecta has been terminated w…
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CLINICAL_TRIALS trial_result · 2022-03-02Clinical Trial Update: A Study in Adult Patients With Type I, III or IV Osteogenesis Imperfecta Treated With BPS804 [Phase 2]
Phase 2 trial update for BPS804 in adults with Osteogenesis Imperfecta types I, III, and IV has completed with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2021-05-11Clinical Trial Update: Safety, Pharmacokinetics and Pharmacodynamics of BPS804 in Osteogenesis Imperfecta [Phase 2]
Phase 2 clinical trial update on safety, pharmacokinetics, and pharmacodynamics of BPS804 in Osteogenesis Imperfecta completed.
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CLINICAL_TRIALS trial_result · 2020-11-10Clinical Trial Update: Boost to Brittle Bones - Stem Cell Transplantation for Treatment of Brittle Bones [Phase 1, Phase 2]
Clinical trial update on stem cell transplantation for Osteogenesis Imperfecta across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2019-04-24Clinical Trial Update: Study of Teriparatide (FORTEO) to Treat Adults With Osteogenesis Imperfecta [Phase 4]
Phase 4 clinical trial update evaluating teriparatide (FORTEO) for adults with osteogenesis imperfecta; study completed with results posted …
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: Nutritional Interventional in Pediatric Patients With Osteogenesis Imperfecta [NA]
Clinical trial evaluating a nutritional intervention in pediatric patients with osteogenesis imperfecta has completed. Sponsored by Hospital…
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CLINICAL_TRIALS trial_result · 2019-01-29Clinical Trial Update: Growth Hormone Therapy in Osteogenesis Imperfecta [Phase 3]
A Phase 3 trial of growth hormone therapy for osteogenesis imperfecta has completed and posted results in 2019.