Osteogenesis Imperfecta
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis Imperfecta [Phase 3]
Phase 3 pediatric safety follow-up study evaluating prior romosozumab treatment in Osteogenesis Imperfecta is currently recruiting. The spon…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Osteogenesis Imperfecta Trial of AGA2115 for ADUlts With COL1A1 and/or COL1A2 GeNetic Variations (IDUN) [Phase 2]
Phase 2 clinical trial update for AGA2115 in adults with Osteogenesis Imperfecta carrying COL1A1/COL1A2 variations; the study is currently r…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Setrusumab vs Placebo for Osteogenesis Imperfecta [Phase 2, Phase 3]
Clinical trial update indicates a Phase 2/Phase 3 study of Setrusumab versus Placebo for Osteogenesis Imperfecta is currently not recruiting…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Setrusumab vs Bisphosphonates in Pediatric Subjects With Osteogenesis Imperfecta [Phase 3]
Phase 3 clinical trial comparing setrusumab to bisphosphonates in pediatric Osteogenesis Imperfecta; currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD) [NA]
A clinical trial update for REMS25 evaluating REMS technology in diseases commonly associated with reduced bone mineral density; recruitment…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Dental Malocclusion and Craniofacial Development in OI
This Clinical Trials update reports on a study examining dental malocclusion and craniofacial development in osteogenesis imperfecta. The st…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Prospective Observational Cohort Study of Cardiac Structure and Function in Children and Adults With Osteogenesis Imperfecta
Prospective observational cohort study assessing cardiac structure and function in children and adults with Osteogenesis Imperfecta; current…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Effects of Bisphosphonates on OI-Related Hearing Loss [Phase 4]
Phase 4 clinical trial is evaluating the effects of bisphosphonates on hearing loss associated with Osteogenesis Imperfecta and is currently…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Clear Aligners for the Treatment of Dental Malocclusion in OI [NA]
Clinical trial update indicates a study evaluating clear aligners to treat dental malocclusion in Osteogenesis Imperfecta; the trial is curr…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Urinary Biomarkers of OI Pathobiology
An ongoing Baylor College of Medicine study investigating urinary biomarkers related to osteogenesis imperfecta is currently active but not …
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Registry of Osteogenesis Imperfecta
This clinical trial registry entry covers an ongoing study of Osteogenesis Imperfecta led by Luca Sangiorgi. The study is currently recruiti…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Mesenchymal Cell Therapy in Osteogenesis Imperfecta (OI) [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating mesenchymal cell therapy for Osteogenesis Imperfecta (including Type III) is not yet recruiting.…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Boost Brittle Bones Before Birth [Phase 1, Phase 2]
Clinical trial update for a Phase 1/2 study in Osteogenesis Imperfecta to boost fetal bone development. The trial is currently active but no…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Audio-vestibular Evaluation of Children and Young Adults With Osteogenesis Imperfecta
A clinical trial is recruiting to evaluate audio-vestibular function in children and young adults with Osteogenesis Imperfecta.
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: BBD Longitudinal Study of Osteogenesis Imperfecta
This entry provides an update on the BBD Longitudinal Study of Osteogenesis Imperfecta led by Baylor College of Medicine, a trial studying O…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Increasing Knowledge on Osteogenesis Imperfecta by Collecting Epidemiological Data [NA]
An ongoing observational epidemiological study on osteogenesis imperfecta led by Istituto Ortopedico Rizzoli to increase knowledge about the…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Social Cognition in Dystrophinopathies and Neurodevelopmental Disorders
A clinical trial update notes a NOT_YET_RECRUITING study examining social cognition in Duchenne muscular dystrophy, Becker muscular dystroph…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Telescoping Nail in Osteogenesis Imperfecta [NA]
This clinical trial update concerns a telescoping nail for Osteogenesis Imperfecta. The study is currently active but not recruiting, sponso…
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CLINICAL_TRIALS research · 2023-08-22Clinical Trial Update: Prevention of Post Operative Bone Loss in Children [NA]
Clinical trial on prevention of postoperative bone loss in children completed, with results posted in 2023.
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CLINICAL_TRIALS research · 2017-05-30Clinical Trial Update: Diagnosis of Osteogenesis Imperfecta in Children
The update centers on a clinical trial investigating diagnostic approaches for osteogenesis imperfecta in children; the status is not provid…
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CLINICAL_TRIALS research · 2016-01-20Clinical Trial Update: Effects of a Physical Rehabilitation Program Using the Nintendo Wii on Children With Osteogenesis Imperfecta (OI) [NA]
A clinical trial evaluating a Nintendo Wii-based physical rehabilitation program for children with Osteogenesis Imperfecta has been terminat…