Oropharyngeal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Training Swallowing Initiation During Expiration [NA]
A recruiting clinical trial from Northwestern University studies training swallowing initiation during expiration for head and neck cancer p…
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CLINICAL_TRIALS withdrawal · 2025-07-11Clinical Trial Update: A Window of Opportunity Study of Black Raspberry for Patients With HNSCC [EARLY_Phase 1]
An early-phase 1 trial evaluating black raspberry for patients with squamous cell carcinoma of the oral cavity or oropharynx has been withdr…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Testing the Addition of M6620 (VX-970, Berzosertib) to Usual Chemotherapy and Radiation for Head and Neck Cancer [Phase 1]
Phase 1 trial evaluating the addition of M6620 (berzosertib; VX-970) to standard chemotherapy and radiation for head and neck cancers, inclu…
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: Prospective Clinical Study to Assess the Safety and Efficacy of Versius, in Transoral Robotic Surgery [NA]
This document announces the completion of a prospective clinical study assessing the safety and efficacy of the Versius transoral robotic sy…
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: Identification of Individual Histological and Blood Markers in Patients With Recurrent or Metastatic Upper Aerodigestive Tract Squamous Cell Carcinoma in Response to Immunotherapies [NA]
A sponsor-initiated clinical trial is recruiting to identify histological and blood biomarkers in patients with recurrent or metastatic uppe…
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CLINICAL_TRIALS withdrawal · 2025-06-22Clinical Trial Update: A Study of HB-202/HB-201 With Pembrolizumab in Patients With HPV16+ Recurrent/Metastatic Oropharyngeal Cancer [Phase 2, Phase 3]
A Phase 2/Phase 3 trial evaluating HB-202/HB-201 with pembrolizumab in HPV16-positive recurrent/metastatic oropharyngeal squamous cell carci…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Post-treatment Surveillance in HPV+ Oropharyngeal SCC
Clinical trial NCT04965792 at Dana-Farber Cancer Institute is currently active but not recruiting, focusing on post-treatment surveillance i…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Neoadjuvant Tislelizumab Plus Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer (NeoSPOT) [Phase 2]
Phase 2 NeoSPOT trial is evaluating neoadjuvant tislelizumab in combination with chemotherapy for locally advanced oral squamous cell carcin…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: People Living With HIV, Oral and Oropharyngeal Cancer, and Health Equity
A UCSF-sponsored clinical trial is currently recruiting to study HIV infections, oral squamous cell carcinoma, and oropharyngeal squamous ce…
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: Exosome Testing as a Screening Modality for Human Papillomavirus-Positive Oropharyngeal Squamous Cell Carcinoma
A completed clinical trial evaluated exosome testing as a screening modality for HPV-positive oropharyngeal squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma [EARLY_Phase 1]
Early-phase 1 clinical trial evaluating durvalumab with or without metformin in head and neck squamous cell carcinoma, including oral cavity…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer [Phase 2, Phase 3]
A trial update on de‑intensified radiation therapy with either cisplatin chemotherapy or nivolumab immunotherapy for early-stage HPV-positiv…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Adjuvant Treatment Deintensification After Transoral Surgery for Human Papillomavirus-Positive Squamous Cell Carcinoma [NA]
This entry reports on a clinical trial investigating deintensification of adjuvant therapy after transoral surgery for HPV-positive orophary…
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery [Phase 1]
A Phase 1 clinical trial is evaluating intratumoral lidocaine injection prior to surgery in patients with oropharyngeal cancer and is curren…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC
A prospective observational study sponsored by UNC Lineberger to validate circulating HPV DNA and prognostic genomic biomarkers in HPV-assoc…
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: Chemoimmunotherapy With or Without SBRT Before Surgery for Locally Advanced Oral and Oropharyngeal Cancer [Phase 2]
Phase 2 clinical trial update evaluating chemoimmunotherapy with or without SBRT before surgery for locally advanced oral and oropharyngeal …
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CLINICAL_TRIALS withdrawal · 2025-04-04Clinical Trial Update: Vorinostat in Combination With Chemoradiation in Locally Advanced HPV Negative HNSCC [Phase 2]
Phase 2 trial of vorinostat with chemoradiation for locally advanced head and neck squamous cell carcinoma has been withdrawn.
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Role of Microbiome as a Biomarkers in Locoregionally-Advanced Oropharyngeal Squamous Cell Carcinoma 2 [NA]
This ClinicalTrials.gov update describes a study investigating the role of the microbiome as biomarkers in locoregionally-advanced oropharyn…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Durvalumab Before Surgery in Treating Patients With Oral Cavity or Oropharynx Cancer [EARLY_Phase 1]
Phase 1 trial evaluating durvalumab given before surgery in patients with oral cavity and/or oropharyngeal squamous cell carcinoma; the stud…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Tolinapant and Radiation for Cisplatin-Ineligible, Previously Untreated, Locally Advanced Head and Neck Cancer [EARLY_Phase 1]
Early-phase trial evaluating Tolinapant in combination with radiation for cisplatin-ineligible, previously untreated locally advanced head a…
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CLINICAL_TRIALS withdrawal · 2025-02-14Clinical Trial Update: NT-I7 for the Treatment of Recurrent Squamous Cell Carcinoma of Head and Neck Undergoing Surgery [Phase 1]
A Phase 1 trial of NT-I7 for recurrent squamous cell carcinoma of the head and neck undergoing surgery was terminated.
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Onalespib in Treating Patients With Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck Receiving Radiation Therapy and Cisplatin [Phase 1]
Phase 1 trial evaluating the safety and tolerability of Onalespib in combination with radiation therapy and cisplatin for locoregionally adv…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: Patients with Human Papillomavirus-associated Head and Neck Cancer for the Discovery of Predictive Biomarkers to Guide Clinical Intervention
This study aims to identify predictive biomarkers to guide clinical intervention in patients with oropharyngeal squamous cell carcinoma, inc…
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CLINICAL_TRIALS trial_result · 2025-02-05Clinical Trial Update: Improving Detection and Early Action for HPV-positive Oropharynx Cancer [NA]
Completed clinical trial evaluating methods for improved detection and early action in HPV-positive oropharyngeal squamous cell carcinoma.
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: Detection of Oral and Throat Cancers Using OralViome Cancer Testing System
This clinical trial update describes using the OralViome Cancer Testing System to detect oral squamous cell carcinoma, oropharyngeal squamou…