Oropharyngeal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: Validity of Viome's Oral/throat Cancer Test
A clinical trial is evaluating the validity of Viome's oral/throat cancer test and is currently recruiting participants.
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer [Phase 2]
Phase 2 trial evaluating de-escalated adjuvant radiation with adjuvant nivolumab in intermediate-high risk HPV-positive oropharyngeal squamo…
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: Phase II Clinical Trial of De-Intensified Therapy in Human Papilloma Virus (HPV) Associated Oropharyngeal Squamous Cell Carcinoma [Phase 2]
Phase II clinical trial evaluating de-intensified therapy for HPV-associated oropharyngeal squamous cell carcinoma is currently not recruiti…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Pembrolizumab & Cabozantinib in Patients With Head and Neck Squamous Cell Cancer [Phase 2]
Phase 2 trial evaluating the combination of pembrolizumab and cabozantinib in head and neck squamous cell carcinoma reported results, with r…
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: Preoperative Tislelizumab -Cetuximab - Chemotherapy Followed by Salvage Surgery and Adjuvant Tislelizumab -Cetuximab for Resectable, Locally Recurrent Oral and Oropharyngeal Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial is planned to evaluate preoperative tislelizumab with cetuximab and chemotherapy followed by salvage surgery, plus …
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer [Phase 1]
This Phase 1 trial update reports the completion of a study evaluating image-guided proton therapy for locally advanced unresectable head an…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Ex Vivo 3D-ultrasound for Oropharyngeal Cancer [NA]
A completed clinical trial evaluating ex vivo 3D-ultrasound for oropharyngeal squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Neoadjuvant Sintilimab in Combination With Carboplatin and Nab-paclitaxel in Resectable Oral Cavity or Oropharyngeal Squamous Cell Carcinoma [Phase 2]
Phase 2 neoadjuvant trial evaluating sintilimab in combination with carboplatin and nab-paclitaxel for resectable oral cavity and oropharyng…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Phase 1 Clinical Trial of FluBHPVE6E7 Immunotherapy for HPV16-Associated Oropharyngeal Cancer [Phase 1]
Phase 1 clinical trial evaluating FluBHPVE6E7 immunotherapy for HPV16-associated oropharyngeal squamous cell carcinoma; the study is current…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer [Phase 1]
Phase 1 trial of nab-paclitaxel (albumin-bound paclitaxel) with carboplatin followed by chemoradiation in patients with recurrent head and n…
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CLINICAL_TRIALS withdrawal · 2024-07-25Clinical Trial Update: Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer [Phase 2]
Phase 2 trial evaluating Xevinapant added to standard radiation therapy plus cisplatin/carboplatin for head and neck cancers has been withdr…
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin [Phase 2]
Phase 2 trial evaluating sodium thiosulfate to prevent cisplatin-induced ototoxicity in patients with head and neck squamous cell carcinoma …
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CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal Cancer [Phase 2]
A Phase 2 trial is testing a less intensive radiation regimen with chemotherapy for low-risk HPV-positive oropharyngeal cancer and is curren…
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: The Sinai Robotic Surgery Trial in HPV Positive Oropharyngeal Squamous Cell Carcinoma (SCCA) (SIRS TRIAL) [NA]
This update reports the completion of the Sinai Robotic Surgery Trial (SIRS) in HPV-positive oropharyngeal squamous cell carcinoma and notes…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: P53 Mutational Status and cf HPV DNA for the Management of HPV-associated OPSCC [Phase 2]
A Phase 2 clinical trial evaluating P53 mutational status and circulating cell-free HPV DNA as biomarkers to guide management of HPV-associa…
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CLINICAL_TRIALS trial_result · 2024-04-17Clinical Trial Update: Alpelisib in Treating Participants With Transorally Resectable HPV-Associated Stage I-IVA Oropharyngeal Cancer [Phase 2]
Phase 2 trial update for alpelisib in participants with transorally resectable HPV-associated stage I-IVA oropharyngeal squamous cell carcin…
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CLINICAL_TRIALS trial_result · 2024-04-01Clinical Trial Update: Nivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery [Phase 2]
A phase 2 trial evaluated the combination of nivolumab with carboplatin and paclitaxel in patients with stage III-IV head and neck squamous …
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CLINICAL_TRIALS trial_result · 2023-11-03Clinical Trial Update: Swallowing Outcomes and Circulating Tumor DNA in Patients With HPV Related Oropharyngeal Cancer Treated With Transoral Surgery and Reduced Intensity Adjuvant Therapy [Phase 2]
Phase 2 clinical trial update evaluating swallowing outcomes and circulating tumor DNA in HPV-related oropharyngeal cancer treated with tran…
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CLINICAL_TRIALS trial_result · 2023-07-19Clinical Trial Update: Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating ficlatuzumab with or without cetuximab in cetuximab-resistant recurrent or metastatic head and neck squamous cell c…
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CLINICAL_TRIALS trial_result · 2023-03-08Clinical Trial Update: ACTOplus Met XR in Treating Patients With Stage I-IV Oral Cavity or Oropharynx Cancer Undergoing Definitive Treatment [Phase 2]
Phase 2 clinical trial update for ACTOplus Met XR in patients with stage I-IV oral cavity or oropharyngeal cancer undergoing definitive trea…
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CLINICAL_TRIALS trial_result · 2022-12-14Clinical Trial Update: Comparison of Adaptive Dose Painting by Numbers With Standard Radiotherapy for Head and Neck Cancer. [Phase 2]
Phase 2 clinical trial comparing adaptive dose painting by numbers with standard radiotherapy for head and neck cancer has completed.
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CLINICAL_TRIALS trial_result · 2022-10-12Clinical Trial Update: OPSCC N0 Nodal Control With Reduced IMRT [NA]
Clinical trial update for OPSCC with reduced IMRT in HPV-associated disease; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2022-09-01Clinical Trial Update: The Quarterback Trial: Reduced Dose Radiotherapy for HPV+ Oropharynx Cancer [Phase 3]
Phase 3 trial evaluating reduced-dose radiotherapy for HPV-positive oropharyngeal cancer has posted results.
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CLINICAL_TRIALS trial_result · 2022-01-25Clinical Trial Update: Combination Chemotherapy With or Without Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck [Phase 2]
This Phase 2 trial evaluated chemotherapy with or without erlotinib in patients with metastatic or recurrent head and neck squamous cell car…
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CLINICAL_TRIALS trial_result · 2021-01-08Clinical Trial Update: Nab-paclitaxel and Carboplatin Followed by Response-Based Local Therapy in Treating Patients With Stage III or IV HPV-Related Oropharyngeal Cancer [Phase 2]
Phase 2 trial evaluating nab-paclitaxel and carboplatin followed by response-based local therapy for HPV-related oropharyngeal cancer (Stage…