Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2025-04-24Clinical Trial Update: Brigatinib Plus Chemotherapy or Local Consolidation Therapy in ALK Positive Advanced Non-small Cell Lung Cancer (BrightStar-2) [Phase 2]
The BrightStar-2 Phase 2 trial evaluating brigatinib in combination with chemotherapy or local consolidation therapy for ALK-positive advanc…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Study of NEO-201 in Solid Tumors Expansion Cohorts [Phase 1, Phase 2]
Precision Biologics is expanding cohorts in a Phase 1/2 study of NEO-201 in solid tumors, including non-small cell lung cancer, head and nec…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: A Pilot Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) in Central Non-Small Cell Lung Cancer [NA]
This clinical trial update notes a pilot study evaluating single-fraction stereotactic body radiation therapy (SBRT) for central non-small c…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors [Phase 1]
Phase 1 trial update studying the immune effects of a fermented wheat germ extract added to standard checkpoint inhibitor therapy in patient…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Exploration of Risk Factors for Postoperative Cerebral Infarction in Lung Cancer Patients: a Retrospective Single-centre Study
A retrospective, single-centre study examining risk factors for postoperative cerebral infarction in patients with non-small cell lung cance…
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: A Study of the Oral EGFR Inhibitor PLB1004 in Non-Small Cell Lung Cancer [Phase 1]
A Phase 1 clinical trial is evaluating PLB1004, an oral EGFR inhibitor, in patients with non-small cell lung cancer and is currently recruit…
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: A Study to Compare Effects and Safety of CT-P51 and Keytruda in Patients With Previously Untreated Metastatic Lung Cancer [Phase 3]
A Phase 3 trial evaluating CT-P51 versus pembrolizumab (Keytruda) in patients with previously untreated metastatic non-small cell lung cance…
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CLINICAL_TRIALS trial_result · 2025-04-23Clinical Trial Update: EF-36/Keynote B36: A Pilot, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150 kHz) Concomitant With Pembrolizumab for First Line Treatment of Advanced or Metastatic Non-small Cell Lung Cancer [Phase 2]
A Phase 2 pilot trial evaluating Tumor Treating Fields (TTFields) in combination with pembrolizumab as first-line therapy for advanced or me…
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: Evaluate Safety and Tolerability of RX001 in Patients With KRAS Mutant Advanced NSCLC [Phase 1]
A Phase 1 trial is evaluating the safety and tolerability of RX001 in patients with KRAS-mutant advanced non-small cell lung cancer; the stu…
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: ctDNA Analysis to Monitor the Risk of Progression After First-line Immunotherapy in Patients With Advanced NSCLC
This clinical trial update describes a study using circulating tumor DNA analysis to monitor the risk of disease progression after first-lin…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: A Safety and Tolerability Study of NC762 in Subjects With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 safety and tolerability study of NC762 in patients with advanced or metastatic solid tumors has been terminated, with results po…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Telehealth Based Synchronous Navigation to Improve Molecularly-Informed Care for Patients With Lung Cancer [NA]
Update on a terminated clinical trial evaluating telehealth-based synchronous navigation to improve molecularly-informed care for patients w…
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Neoadjuvant Nivolumab Plus Ipilimumab in Resectable NSCLC (GALAXY 3) [Phase 2]
Phase 2 GALAXY 3 trial assessing neoadjuvant nivolumab plus ipilimumab in resectable non-small cell lung cancer; currently recruiting.
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Prehabilitation for Patients Undergoing Lung Cancer Surgery [NA]
A clinical trial evaluating prehabilitation before lung cancer surgery in patients with non-small cell lung cancer; recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Development of New Methodologies and Innovative Tools for the diagnoSi and Therapeutic Treatment of uMAni Epithelial Tumors
A recruiting clinical trial update from ASL Lecce on developing new methodologies and innovative tools for diagnosing and treating human epi…
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CLINICAL_TRIALS other · 2025-04-22Clinical Trial Update: Cryoablation Combined With Tislelizumab and Chemotherapy as Neoadjuvant and Adjuvant Therapy in Resectable Stage II-IIIB NSCLC [Phase 2]
Phase 2 clinical trial evaluating cryoablation with tislelizumab and chemotherapy as neoadjuvant and adjuvant therapy for resectable stage I…
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: Third-generation EGFR-TKI Treatment in Metastatic EGFR-mutant NSCLC
A trial update notes the completion of a study evaluating a third-generation EGFR-TKI in metastatic EGFR-mutant non-small cell lung cancer.
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: A Multicenter, Single-arm Phase II Study to Evaluate the Efficacy and Safety of Fulzerasib (IBI351) in Combination With Ivonescimab (AK-112) in First-line Treatment of Advanced or Metastatic Non-small Cell Lung Cancer Patients With KRAS G12C Mutation [Phase 2]
Phase II multicenter single-arm study evaluating Fulzerasib (IBI351) in combination with Ivonescimab (AK-112) as first-line treatment for ad…
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Study of an Anti-HER3 Antibody, HMBD-001, With or Without Chemotherapy in Patients With Solid Tumors Harboring an NRG1 Fusion or HER3 Mutation [Phase 1]
Phase 1 clinical trial update of HMBD-001, an anti-HER3 antibody, evaluating its use with or without chemotherapy in solid tumors with NRG1 …
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CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: Hippocampus-Avoidance Whole-Brain Radiation Therapy With Simultaneous Integrated Boost for BMs of NSCLC [NA]
Clinical trial update on hippocampus-avoidance whole-brain radiation therapy with simultaneous integrated boost for brain metastases from no…
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CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: Machine Learning Approaches to Personalized Therapy for Advanced Non-small Cell Lung Cancer With Real-World Data
A clinical trial from the University of Utah is exploring machine learning methods to tailor therapy for advanced non-small cell lung cancer…
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CLINICAL_TRIALS trial_result · 2025-04-17Clinical Trial Update: Sitravatinib Plus Pembrolizumab in Patients With Advanced Treatment-Naïve PD-L1+ Non-Squamous NSCLC [Phase 2]
Phase 2 trial evaluating sitravatinib plus pembrolizumab in advanced treatment-naïve PD-L1-positive non-squamous non-small cell lung cancer …
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: A Study of DM001 in Patients With Advanced Solid Tumors [Phase 1]
A Phase 1 clinical trial evaluating DM001 in patients with advanced solid tumors, currently recruiting.
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CLINICAL_TRIALS withdrawal · 2025-04-17Clinical Trial Update: Local Consolidative Radiotherapy for Oligoprogressive in Non-small Cell Lung Carcinoma [Phase 2]
Phase 2 trial evaluating local consolidative radiotherapy for oligoprogressive non-small cell lung cancer has been withdrawn.
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: A Study of SHR-1826 for Injection in Combination With Other Antitumor Therapies in Subjects With NSCLC [Phase 1, Phase 2]
This clinical trial update reports that SHR-1826 is being studied in combination with other antitumor therapies for non-small cell lung canc…