Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: A Prospective Study: the Impact of Sleep Disturbances on Immunotherapy in Patients With Lung Cancer
A prospective clinical trial assessing how sleep disturbances and circadian rhythm affect immunotherapy outcomes in patients with non-small …
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: Exercise as Maintenance Therapy in Advanced Lung Cancer [NA]
A clinical trial update noting recruitment for a study of exercise as maintenance therapy in advanced lung cancer, including non-small cell …
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CLINICAL_TRIALS trial_result · 2025-04-30Clinical Trial Update: Prognostic Value of Tumor Hypoxia, as Measured by 18F-FMISO Breath Hold PET/CT, in Non-Small-Cell-Lung Cancer (NSCLC) Patients [NA]
This clinical trial update reports on the prognostic value of tumor hypoxia in non-small cell lung cancer as measured by 18F-FMISO breath-ho…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: SBRT for Oligo-residual NSCLC After Treatment With PD-1/PD-L1 Immune Checkpoint Inhibitors [Phase 2]
A Phase 2 clinical trial is evaluating stereotactic body radiotherapy for oligo-residual non-small cell lung cancer after prior treatment wi…
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CLINICAL_TRIALS trial_result · 2025-04-30Clinical Trial Update: A Clinical Evaluation of AI Solutions Developed in the CHAIMELEON Project for Cancer: Prostate, Lung, Breast, Colon and Rectum
Clinical trial update indicating the CHAIMELEON AI solution evaluation for prostate, breast, colon, rectal, and non-small cell lung cancers …
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CLINICAL_TRIALS trial_result · 2025-04-30Clinical Trial Update: Induction Chemo-Nivo in Unresectable Stage III NSCLC [Phase 2]
Phase 2 trial evaluating induction chemotherapy with nivolumab for unresectable stage III non-small cell lung cancer has been terminated. Re…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: IN10018 Combination Therapy in Advanced EGFR Mutation-positive NSCLC [Phase 1, Phase 2]
An ongoing Phase 1/2 trial evaluating the IN10018 combination therapy for advanced EGFR mutation-positive non-small cell lung cancer is curr…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: Multiomics Tumor Evolution Model of NSCLC
A multiomics study exploring tumor evolution in non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: Integrin αvβ6-targeted PET in Malignant Tumors
A recruiting clinical trial evaluating an integrin αvβ6-targeted PET tracer for imaging malignant tumors, including non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: Study of the Efficacy and Safety of Ponsegromab in Patients With Cancer, Cachexia and Elevated GDF-15 [Phase 2]
Phase 2 trial of ponsegromab in cancer patients with cachexia and elevated GDF-15 completed; results posted.
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: MIDRIXNEO-LUNG Dendritic Cell Vaccine in Patients With Non-small Cell Lung Cancer [Phase 1]
Phase 1 clinical trial update for the MIDRIXNEO-LUNG Dendritic Cell Vaccine in non-small cell lung cancer; the study at University Hospital …
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating Sutetinib Maleate Capsule for locally advanced or metastatic non-small cell lung cancer; recruitment is cu…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: Genetics and Shared Decision Making in Improving Care for Patients With Stage IVA-C Non-small Cell Lung Cancer [NA]
A completed clinical trial from Thomas Jefferson University evaluated how integrating genetic information and shared decision making affects…
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy) [Phase 2]
Phase 2 clinical trial update for Zenocutuzumab (MCLA-128) in solid tumors harboring NRG1 fusions, including non-small cell lung cancer and …
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: A Study to Evaluate the Clinical Efficacy of JNJ-42756493 (Erdafitinib), A Pan-Fibroblast Growth Factor Receptor (FGFR) Tyrosine Kinase Inhibitor, In Asian Participants With Advanced Non-Small-Cell Lung Cancer, Urothelial Cancer, Esophageal Cancer Or Cholangiocarcinoma [Phase 2]
A Phase 2 study completed in Asian participants evaluated Erdafitinib, a pan-FGFR tyrosine kinase inhibitor, for efficacy in advanced non-sm…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: Comparison of Neoadjuvant Cadonilimab Versus Chemotherapy Combined With PD-1 in the Treatment of Resectable Non-Small Cell Lung Cancer With High PD-L1 Expression: A Single-Center, Randomized, Exploratory Clinical Study [Phase 2]
A Phase 2, single-center randomized exploratory trial comparing neoadjuvant Cadonilimab versus chemotherapy with a PD-1 inhibitor in resecta…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: First-in-Human Study of BBT-207 in Advanced Non-Small Cell Lung Cancer Harboring EGFR Mutation After Treatment With EGFR TKI [Phase 1, Phase 2]
First-in-human Phase 1/2 trial of BBT-207 in EGFR-mutant advanced non-small cell lung cancer after prior EGFR TKI therapy is underway.
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: A Real-world Study on the Treatment of Non-small Cell Lung Cancer With Leptomeningeal Metastasis in China
Clinical trial update for a real-world study in China assessing treatment of leptomeningeal metastasis from non-small cell lung cancer; the …
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EMA approval · 2025-04-25EMA Authorised: Alunbrig (brigatinib) — Takeda Pharma A/S
The EMA has authorised Alunbrig (brigatinib) for non-small cell lung cancer, with Takeda Pharma A/S as the marketing authorization holder.
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression [Phase 1, Phase 2]
A2 Biotherapeutics is evaluating A2B530, a logic-gated CAR T therapy, in Phase 1/2 trials for CEA-expressing solid tumors that have lost HLA…
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: JS207 Combined With Chemotherapy in Subjects With Stage II-III NSCLC [Phase 2]
A Phase 2 clinical trial of JS207 combined with chemotherapy for stage II-III non-small cell lung cancer is currently not recruiting.
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: Adagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation (KRYSTAL -19) [Phase 1]
A Phase 1 trial evaluating the combination of adagrasib and nab-sirolimus in patients with advanced solid tumors and KRAS G12C-mutant non-sm…
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: A Clinical Trial of Furmonertinib Combined With Anlotinib as First-line Treatment for Advanced NSCLC With EGFR-sensitive Mutations and Brain Metastasis [Phase 2]
Phase 2 clinical trial evaluating furmonertinib in combination with anlotinib as first-line therapy for advanced non-small cell lung cancer …
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: Bronchoscopic Cryo-Immunotherapy of Lung Cancer [EARLY_Phase 1]
Early-phase Phase 1 trial update on bronchoscopic cryo-immunotherapy for advanced non-small cell lung cancer; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: A Study of Sapanisertib in Relapsed/Refractory NFE2L2-Mutated and Wild-Type Squamous Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial of sapanisertib in relapsed/refractory squamous non-small cell lung cancer (including NFE2L2-mutant and wild-type) has been te…