Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: A Study Evaluating the Efficacy of PD-1 Inhibitor Combined With Denosumab and Chemotherapy in Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer Patients With Driver Gene-Negative Status [Phase 2]
A Phase 2 clinical trial is evaluating a PD-1 inhibitor in combination with denosumab and chemotherapy for locally advanced or metastatic no…
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Study to Compare Furmonertinib to Platinum-Based Chemotherapy for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations (FURVENT) [Phase 3]
Phase 3 trial update to compare furmonertinib against platinum-based chemotherapy in locally advanced or metastatic non-small cell lung canc…
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: HER3-DXd (Patritumab Deruxtecan; U3-1402) in Combination With Osimertinib in Subjects With Locally Advanced or Metastatic EGFR-mutated Non-Small Cell Lung Cancer [Phase 1]
A Phase 1 clinical trial update evaluating the combination of Patritumab Deruxtecan (HER3-DXd) with Osimertinib in patients with locally adv…
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
This trial update describes a dose-escalation and dose-expansion study of MDX2001 in patients with advanced solid tumors, currently recruiti…
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: A Single-arm, Multicenter, Prospective Clinical Study of Adebrelimab Combined With Apatinib Neoadjuvant Therapy for Resectable Non-small Cell Lung Cancer [Phase 2]
A Phase 2, single-arm multicenter trial evaluating neoadjuvant therapy with Adebrelimab plus Apatinib for resectable non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: Complication and Lung Function Impairment Prediction Using Perfusion and CT Air Trapping
This completed trial from University Hospital, Montpellier investigates whether perfusion imaging and CT air trapping can predict treatment-…
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CLINICAL_TRIALS trial_result · 2025-06-19Clinical Trial Update: Testing the Safety of Adding Either Monalizumab (IPH2201) or Oleclumab (MEDI9447) to Durvalumab (MEDI4736) Plus Standard Radiation Therapy for Locally Advanced Non-small Cell Lung Cancer (NSCLC), ARCHON-1 Trial [Phase 1]
The ARCHON-1 phase 1 trial updates on the safety of adding either Monalizumab or Oleclumab to Durvalumab with standard radiation therapy for…
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CLINICAL_TRIALS trial_result · 2025-06-19Clinical Trial Update: Telaglenastat Hydrochloride and Osimertinib in Treating Patients With EGFR-Mutated Stage IV Non-small Cell Lung Cancer [Phase 1, Phase 2]
This clinical trial update reports results from a phase 1/2 study of the combination of telaglenastat hydrochloride and osimertinib in patie…
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors [Phase 2]
A Phase 2 clinical trial by Iovance Biotherapeutics evaluating autologous tumor-infiltrating lymphocytes in solid tumors is currently recrui…
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: Radical Resection With Contralateral Lymph Node Dissection for Clinical N3 NSCLC [NA]
A surgical trial evaluating radical resection with contralateral lymph node dissection for clinical N3 non-small cell lung cancer is current…
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: DZD9008 In Combination With Bevacizumab in Locally Advanced or Metastatic NSCLC Patients With EGFR Mutation (WU-KONG29) [Phase 2]
Phase 2 trial evaluating DZD9008 in combination with Bevacizumab for locally advanced or metastatic non-small cell lung cancer with EGFR mut…
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FDA approval · 2025-06-18FDA Approved: AXTLE — Supplemental Application (Avyxa Pharma, LLC)
FDA approved a supplemental application for AXTLE (pemetrexed) submitted by Avyxa Pharma, LLC.
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CLINICAL_TRIALS trial_result · 2025-06-18Clinical Trial Update: APG-2449 in Patients With Advanced Solid Tumors [Phase 1]
A Phase 1 trial of APG-2449 in patients with advanced solid tumors is currently recruiting, including non-small cell lung cancer, esophageal…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Clinical Application Study of PET/CT for Differential Diagnosis of Non-small Cell Lung Cancer [NA]
Clinical trial evaluating the use of PET/CT for differentiating non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-06-17Clinical Trial Update: Long-term Outcomes Among Patients With Programmed Death-ligand 1 <1% Metastatic Non-small Cell Lung Cancer Treated With First-line Nivolumab + Ipilimumab + 2 Cycles of Chemotherapy
This update reports long-term outcomes from a first-line regimen of nivolumab plus ipilimumab with two cycles of chemotherapy for metastatic…
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CLINICAL_TRIALS trial_result · 2025-06-17Clinical Trial Update: Phase Ib First in Human Dose Escalation of GT103 in Refractory, Advanced Stage Non-Small Cell Lung Cancer (TOP 1902) [Phase 1]
Phase Ib first-in-human dose-escalation study of GT103 in patients with refractory, advanced non-small cell lung cancer has completed.
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Spatial Fragmentation Combined With Low-dose Radiotherapy for Immunotherapy Combined With Chemotherapy-resistant Locally Advanced or Advanced Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating spatial fragmentation with low-dose radiotherapy in combination with immunotherapy and chemotherapy for chemo-resis…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: A Study of Canakinumab With Chemotherapy, Radiation Therapy, and Durvalumab in People With Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating canakinumab with chemotherapy, radiation therapy, and durvalumab for non-small cell lung cancer; the stu…
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CLINICAL_TRIALS trial_result · 2025-06-17Clinical Trial Update: Postoperative Telerehabilitation in Older Adults [NA]
A completed clinical trial from Pusan National University Hospital reports results of postoperative telerehabilitation for older adults with…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Randomized Study of Carbon Ion Boost in Hypoxic Lesions for Locally Advanced Non-small Cell Lung Cancer [Phase 2]
A Phase 2 randomized trial is evaluating the addition of a carbon ion boost for locally advanced non-small cell lung cancer with hypoxic les…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Honokiol in Early-Stage Resectable Non-Small Cell Lung Cancer [Phase 1]
Phase 1 clinical trial evaluating honokiol in early-stage resectable non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: A Study of CDX-585 in Patients With Advanced Malignancies [Phase 1]
Phase 1 trial update showing completed enrollment and results for CDX-585 in patients with advanced solid tumors, including non-small cell l…
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Platform Trial of Novel Regimens Versus Standard of Care (SoC) in Participants With Non-small Cell Lung Cancer (NSCLC) [Phase 2]
This Phase 2 platform trial comparing novel regimens against standard of care in non-small cell lung cancer has completed enrollment and pos…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Hybrid Prehabilitation Before Thoracic Surgery [NA]
This document reports a clinical trial update for a hybrid prehabilitation program before thoracic surgery in non-small cell lung cancer pat…
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: A Phase 1/2 Study of BA3071 in Patients With Solid Tumors [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of BA3071 in patients with solid tumors, including non-small cell lung cancer and mel…