Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Feasibility Study of Tissue and Blood Collection in Oncogene-addicted and Neoadjuvantly Treated Non Small Cell Lung Cancer
A feasibility study underway at Royal Marsden NHS Foundation Trust aims to collect tissue and blood samples from patients with oncogene-addi…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: A Study Evaluating Neoadjuvant Chemoimmunotherapy With Immunosensitizing Radiation for Borderline Resectable Non-Small Cell Lung Cancer [Phase 1]
This clinical trial update describes a Phase 1 study evaluating neoadjuvant chemoimmunotherapy with immunosensitizing radiation for border-l…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Molecular Profiling Project
This clinical trial update indicates that the Molecular Profiling Project led by the National Cancer Centre, Singapore is currently recruiti…
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Immunotherapy With or Without SBRT in Patients With Stage IV Non-small Cell Lung Cancer [Phase 3]
A Phase 3 trial evaluating immunotherapy with or without SBRT in patients with stage IV non-small cell lung cancer has completed and posted …
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CLINICAL_TRIALS approval · 2025-06-13Clinical Trial Update: Pre-Approval Access With Amivantamab (JNJ-61186372) in Participants With Metastatic Non-Small Cell Lung Cancer
Amivantamab (Rybrevant) has been approved for marketing for metastatic non-small cell lung cancer, and the update includes information on a …
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: A Study of Dato-DXd in Chinese Patients With Advanced Non-Small Cell Lung Cancer, Triple-negative Breast Cancer and Other Solid Tumors (TROPION-PanTumor02) [Phase 1, Phase 2]
AstraZeneca's Dato-DXd is being studied in a Phase 1/2 trial (TROPION-PanTumor02) in Chinese patients with advanced non-small cell lung canc…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Carbon Ion Therapy for Peripheral Non-small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating carbon ion therapy for peripheral non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Carbon Ion Radiotherapy for Locally Advanced Lung Cancer in Elderly Patients [Phase 2]
Phase 2 clinical trial evaluating carbon ion radiotherapy for locally advanced non-small cell lung cancer in elderly patients. The study is …
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Hypofractionated Boost Before Chemoradiation for Patients With Stage II-III Non-small Cell Lung Cancer Unsuitable for Surgery [Phase 2]
This Phase 2 clinical trial update reports results for a hypofractionated boost before chemoradiation in patients with stage II–III non-smal…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Neoadjuvant WX-0593 in Resectable ALK-positive or ROS1-positive Non-small Cell Lung Cancer [Phase 2]
A phase 2 neoadjuvant trial of WX-0593 for resectable ALK-positive or ROS1-positive non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: The Development, Safety, and Feasibility of an Artificial Intelligence-Powered Platform (NodeAI) for Real-Time Prediction of Mediastinal Lymph Node Malignancy During Endobronchial Ultrasound Staging for Lung Cancer [NA]
The document describes a study to develop and evaluate NodeAI, an AI-powered platform to predict mediastinal lymph node malignancy in real-t…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: SBRT Followed by Neoadjuvant Immunochemotherapy in Resectable Stage II to III Non-small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating stereotactic body radiotherapy (SBRT) followed by neoadjuvant immunochemotherapy in resectable stage II …
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Phase 2 Study of Dacomitinib in NSCLC [Phase 2]
Phase 2 trial evaluating dacomitinib for non-small cell lung cancer (including EGFR-positive NSCLC) is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Plasma Molecular Profiling in ALK Inhibitor Resistant NSCLC
This clinical trial investigates plasma molecular profiling to identify resistance mechanisms in ALK-inhibitor resistant non-small cell lung…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: A Pan-Asian Clinical Database of EGFR Exon 20 Insertion Mutated NSCLC
A Pan-Asian clinical database is being established to study EGFR Exon 20 insertion-mutated non-small cell lung cancer, and the study is curr…
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Study of Lorlatinib In People With ALK-positive Non-small Cell Lung Cancer [Phase 4]
Pfizer's Phase 4 study of lorlatinib in ALK-positive non-small cell lung cancer has completed and results are posted.
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: D-BACE in Combination With Chemotherapy and Carelizumab for Resectable II-IIIA or Potentially Resectable T3-4N2 Stage IIIB NSCLC [Phase 3]
Phase 3 clinical trial evaluating D-BACE in combination with chemotherapy and Carelizumab for resectable II-IIIA or potentially resectable T…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: A Study of DCTY1102 Injection in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study of DCTY1102 Injection in patients with advanced solid tumors, including pancreatic ductal adenocarcinoma, colorectal cancer, n…
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Toward High Fidelity Adaptive Radiotherapy in the Thorax
Clinical trial update on high-fidelity adaptive radiotherapy in the thorax for non-small cell lung cancer; the study status is completed.
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Phase-2 Dacomitinib Study on Patients With EGFR-Driven Advanced Solid Tumours With Low EGFR-AS1 IncRNA Expr or Other Novel Emerging Biomarkers [Phase 2]
Phase-2 study of dacomitinib in EGFR-driven advanced solid tumours, including non-small cell lung cancer and head and neck squamous cell car…
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: AVID100 in Advanced Epithelial Carcinomas [Phase 1, Phase 2]
A phase 1/2 trial of AVID100 for advanced epithelial carcinomas was terminated; results were posted in June 2025.
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: A Study of Neoadjuvant/Adjuvant Durvalumab for the Treatment of Patients With Resectable Non-small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating neoadjuvant/adjuvant durvalumab for resectable non-small cell lung cancer is currently active and not recruiting.
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EMA approval · 2025-06-10EMA Authorised: Rozlytrek (Entrectinib) — Roche Registration GmbH
The EMA authorised Rozlytrek (entrectinib) for cancer with a conditional approval, including non-small cell lung cancer. The marketing autho…
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EMA approval · 2025-06-10EMA Authorised: Apexelsin (paclitaxel) — Whiteoak Pharmaceutical B.V.
The EMA authorised Apexelsin (paclitaxel) for breast cancer, pancreatic cancer, and non-small cell lung cancer, with Whiteoak Pharmaceutical…
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CLINICAL_TRIALS trial_result · 2025-06-10Clinical Trial Update: A Study of EGF816 and Gefitinib in TKI-naïve EGFR-mutant Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 study of EGF816 (osimertinib) in combination with Gefitinib in TKI-naïve EGFR-mutant non-small cell lung cancer was terminated and…