Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: A Study of JS207 (PD-1/VEGF Bispecific Antibody) in Combination With Chemotherapy in Advanced Non-small Cell Lung Cancer [Phase 2]
A Phase 2 study of JS207, a PD-1/VEGF bispecific antibody, in combination with chemotherapy for advanced non-squamous non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: The Food-effect on Alectinib Pharmacokinetics [NA]
A completed clinical trial evaluated the effect of food on the pharmacokinetics of alectinib in patients with non-small cell lung cancer.
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors [Phase 2]
Phase 2 study evaluating APL-101 in non-small cell lung cancer with MET exon 14 skipping mutations and MET dysregulation, as well as other M…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: A Nutritional Supplement to Support People With Non-small Cell Lung Cancer [NA]
This clinical trial update notes an ongoing study of a nutritional supplement to support people with non-small cell lung cancer.
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: A Multicenter Phase II Randomized Trial of Limertinib Followed by Sintilimab and Chemotherapy vs. Limertinib Followed by Limertinib and Chemotherapy as Neoadjuvant Therapy in Resectable Stage II-IIIB EGFR-Mutant NSCLC [Phase 2]
This is a Phase II randomized neoadjuvant trial in resectable EGFR-mutant non-small cell lung cancer comparing limertinib followed by sintil…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Neoadjuvant and Adjuvant Therapy Studies of Sindilizumab in Resectable Lung Cancer [Phase 3]
Phase 3 trials are evaluating sintilimab as neoadjuvant and adjuvant therapy for resectable non-small cell lung cancer. The study status is …
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Outpatient Pulmonary Rehabilitation in Non-small-cell Lung Cancer Receiving Immunotherapy [NA]
An outpatient pulmonary rehabilitation study in patients with non-small-cell lung cancer receiving immunotherapy is currently recruiting. Th…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Early Palliative Care in Patients With Advanced Lung Cancer Using an e-Health Ecosystem [NA]
The trial is investigating early palliative care for patients with advanced non-small cell lung cancer using an electronic health ecosystem.…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Osimertinib to Suppress the Progression of GGN(EGFR Mutation-positive) [Phase 2]
A Phase 2 clinical trial evaluating whether osimertinib can suppress progression of ground-glass nodules in EGFR mutation-positive lung canc…
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CLINICAL_TRIALS withdrawal · 2025-06-26Clinical Trial Update: Similar Efficacy, Safety, and Immunogenicity of FYB206 in Comparison to Keytruda as add-on to Chemotherapy in Patients With Non-squamous Non-small Cell Lung Cancer (NSCLC) [Phase 3]
Phase 3 trial comparing FYB206 to pembrolizumab (Keytruda) as add-on to chemotherapy in non-squamous non-small cell lung cancer has been ter…
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CLINICAL_TRIALS other · 2025-06-26Clinical Trial Update: Neoadjuvant Sugemalimab + Chemotherapy Followed by Adjuvant Sugemalimab for Patients With Resectable Stage II-IIIA Non-small-cell Lung Cancer Patients [Phase 2]
A Phase 2 study evaluating neoadjuvant sugemalimab plus chemotherapy followed by adjuvant sugemalimab for resectable stage II-IIIA non-small…
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CLINICAL_TRIALS safety_alert · 2025-06-25Clinical Trial Update: Interstitial Pneumonitis Associated With EGFR-TKI and Combined With PD-1/PD-L1
A clinical trial update notes cases of interstitial pneumonitis associated with combining EGFR tyrosine kinase inhibitors (EGFR-TKIs) and PD…
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: KEYMAKER-U01 Substudy 3: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in Participants With Advanced Non-small Cell Lung Cancer (NSCLC), Previously Treated With Anti-programmed Cell Death Receptor Ligand 1 (PD-L1) Therapy (MK-3475-01C/KEYMAKER-U01C) [Phase 2]
Phase 2 substudy evaluating pembrolizumab in combination with investigational agents for advanced non-small cell lung cancer in patients pre…
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: Xentuzumab (BI 836845) Plus Afatinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC) [Phase 1]
Phase 1 trial update of Xentuzumab (BI 836845) plus Afatinib in EGFR-mutant non-small cell lung cancer; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: CX3CR1+T Cell Predict Immunotherapy Efficacy
A completed clinical trial from Shanghai Pulmonary Hospital explored whether CX3CR1+ T cells can predict the efficacy of immunotherapy in no…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Maintenance Pembrolizumab at Usual or Low doSE in Non-squamous Lung Cancer: a Non-inferiority Study [Phase 3]
Phase 3 non-inferiority trial evaluating maintenance pembrolizumab at standard versus low dose in metastatic non-small cell lung cancer; cur…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: A Clinical Trail of KJ015 in Patients With HER2-Expressing Solid Tumors [Phase 1]
A Phase 1 trial update for KJ015 in HER2-expressing solid tumors shows the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Adebrelimab + Chemotherapy as Neoadjuvant Therapy for Resectable NSCLC [Phase 2]
A Phase 2 clinical trial evaluating neoadjuvant adebrelimab plus chemotherapy for resectable non-small cell lung cancer, with recruitment no…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Pilot Study of the Contribution of Fractional Exhaled Nitric Oxide as a Prognostic Marker of Response to Anti-PD-L1 Immunotherapy in Non-small Cell Lung Cancer
A pilot clinical study is evaluating whether fractional exhaled nitric oxide can serve as a prognostic biomarker for response to anti-PD-L1 …
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Pembrolizumab for Advanced NSCLC and PS 2-3 [Phase 2]
A Phase 2 clinical trial evaluating pembrolizumab for advanced non-small cell lung cancer with performance status 2-3 is currently recruitin…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Efficacy and Safety of Chemoimmunotherapy and Carbon Ion Radiotherapy in Unresectable Locally Advanced Non-small Cell Lung Cancer
This clinical trial update describes a study evaluating the efficacy and safety of chemoimmunotherapy combined with carbon ion radiotherapy …
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Enteral Nutrition With L-Carnitine for Cachexia in Non-Small Cell Lung Cancer [NA]
This clinical trial investigates enteral nutrition supplemented with L-Carnitine to address cachexia in patients with non-small cell lung ca…
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: Electroacupuncture Combined With Immune Checkpoint Inhibitors as Adjuvant Therapy After Surgery for Early-stage Non-small Cell Lung Cancer [Phase 2, Phase 3]
This clinical trial entry describes an ongoing Phase 2/Phase 3 study evaluating electroacupuncture plus immune checkpoint inhibitors as adju…
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: A Study of Ociperlimab With Tislelizumab Compared to Pembrolizumab in Participants With Untreated Lung Cancer [Phase 3]
Phase 3 clinical trial evaluating ociperlimab with tislelizumab versus pembrolizumab in untreated non-small cell lung cancer; the study is a…
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: SSGJ-707 in Advanced Non-Small Cell Lung Cancer [Phase 3]
Phase 3 clinical trial update for the investigational drug SSGJ-707 in advanced non-small cell lung cancer; currently recruiting.