Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: Phase II Study of SHR-1210(Anti-PD-1 Antibody) Combination With Apatinib Versus Pemetrexed and Carboplatin in Subjects With KRAS Mutant Stage IV Non-squamous Non-small Cell Lung Cancer [Phase 2]
Phase II trial comparing SHR-1210 (camrelizumab) plus apatinib vs pemetrexed plus carboplatin in KRAS-mutant stage IV non-squamous non-small…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy [NA]
A City of Hope Medical Center-led clinical trial is evaluating geriatric assessment and management for older adults with non-small cell lung…
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CLINICAL_TRIALS approval · 2025-07-03Clinical Trial Update: Medical Access Program for Datopotamab Deruxtecan in EGFRm NSCLC Patients
Datopotamab Deruxtecan has been approved for marketing in EGFR-mutant non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Platform Trial of Novel Regimens Versus Standard of Care (SoC) in Participants With Non-small Cell Lung Cancer (NSCLC) - Sub-study 3 [Phase 2]
Phase 2 platform trial evaluating novel regimens versus standard of care in non-small cell lung cancer (NSCLC), Sub-study 3, has completed w…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Low Dose Nivolumab With Chemotherapy vs Standard Chemotherapy as First-Line Treatment in Advanced or Metastatic NSCLC [Phase 3]
Phase 3 trial evaluating low-dose nivolumab in combination with chemotherapy versus standard chemotherapy as first-line treatment for advanc…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Microbiota Transplant to Cancer Patients Who Have Failed Immunotherapy Using Faeces From Clinical Responders [Phase 2]
A Phase 2 clinical trial at Oslo University Hospital is testing fecal microbiota transplantation from clinical responders in cancer patients…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Study of Intravenous (IV) ABBV-637 Alone or in Combination With IV Docetaxel/Osimertinib to Assess Adverse Events and Change in Disease Activity in Adult Participants With Relapsed/Refractory (R/R) Solid Tumors [Phase 1]
This Phase 1 clinical trial from AbbVie tests ABBV-637 alone or in combination with intravenous docetaxel or osimertinib in adults with rela…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Extracellular Vesicles and Particles (EVP) as Biomarkers of Recurrence in Non-Small Cell Lung Cancer
This clinical trial is evaluating extracellular vesicles and particles as biomarkers of recurrence in non-small cell lung cancer and is curr…
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CLINICAL_TRIALS other · 2025-07-03Clinical Trial Update: A Study of the Combination of Osimertinib, Platinum and Etoposide for Patients With Metastatic EGFR Mutant Lung Cancers [Phase 1]
A phase 1 clinical trial at Memorial Sloan Kettering is evaluating the combination of osimertinib with platinum-based chemotherapy and etopo…
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: [18F]F-AraG/Total Body PET Imaging and Healthy Subjects and Lung Cancer Patients [EARLY_Phase 1]
The document reports results from an early Phase 1 trial evaluating the [18F]F-AraG total-body PET imaging agent in healthy subjects and pat…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Clinical Safty and Efficacy Study of Infusion of iNKT Cells and CD8+T Cells in Patients With Advanced Solid Tumor [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the safety and efficacy of infusions of iNKT cells and CD8+ T cells in patients with advanced solid tu…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: A Phase Ib Study of JMKX001899 in Combination With Other Therapies in Advanced NSCLC Harboring KRAS G12C Mutation [Phase 1]
Phase Ib clinical trial update for JMKX001899 in combination with other therapies for advanced non-small cell lung cancer harboring KRAS G12…
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: PANK-003 Cell Injection Combined With Standard Adjuvant Chemotherapy After Surgery in Patients With Stage IIIA NSCLC [Phase 2]
Describes a Phase 2 trial of PANK-003 cell injection with standard adjuvant chemotherapy for stage IIIA non-small cell lung cancer, with the…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Primary Resistance Mechanisms of ALK TKIs
This clinical trial entry outlines a study to investigate primary resistance mechanisms to ALK inhibitors in patients with ALK-positive adva…
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CLINICAL_TRIALS withdrawal · 2025-07-01Clinical Trial Update: A Study to Investigate LYL797 in Adults With Solid Tumors [Phase 1]
Lyell Immunopharma's Phase 1 study of LYL797 in adults with solid tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: A Study to Investigate LYL845 in Adults With Solid Tumors [Phase 1]
Lyell Immunopharma reports termination of the Phase 1 trial evaluating LYL845 in adults with solid tumors, including melanoma, non-small cel…
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: A Study of Biomarker-Directed, Pembrolizumab (MK-3475) Based Combination Therapy for Advanced Non-Small Cell Lung Cancer (MK-3475-495/KEYNOTE-495) [Phase 2]
This is a Phase 2 clinical trial update for a biomarker-directed pembrolizumab-based combination therapy in advanced non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: A Biomarker Screening Protocol for Participants With Solid Tumors
A clinical trial update describes a biomarker screening protocol for participants with solid tumors, and the study has been terminated.
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Tislelizumab in Combination With Sitravatinib in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating tislelizumab in combination with sitravatinib for locally advanced or metastatic non-small cell lung cancer was ter…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: A Prospective, Single-arm, Phase II Clinical Study of Tislelizumab Combined With Anlotinib and Platinum-based Doublet Perioperative Therapy for Resectable Stage II-IIIB Driver Gene-negative NSCLC [Phase 2]
A Phase II, single-arm study evaluating tislelizumab in combination with anlotinib and platinum-based chemotherapy as perioperative therapy …
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Risk and Prognosis of Brain Metastasis in Non-Small Cell Lung Cancer
A registered clinical trial sponsored by Fudan University investigates the risk and prognosis of brain metastases in patients with non-small…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Exercise and Nutrition on Early-stage NSCLC Outcomes: the STARLighT Study [NA]
A clinical trial update for the STARLighT study testing exercise and nutrition as interventions for outcomes in early-stage non-small cell l…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: A Confirmatory Clinical Study in NSCLC Patients With MET Exon 14 Mutation (KUNPENG-2) [Phase 3]
This is a status update for a Phase 3 confirmatory trial in non-small cell lung cancer patients with MET exon 14 mutation, currently recruit…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Clinical Outcomes of Tislelizumab Combined With Chemotherapy as Induction Therapy in Stage III (cTNM-IIIB/IIIC) NSCLC
The document reports clinical outcomes from a trial evaluating tislelizumab in combination with chemotherapy as induction therapy for stage …
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Oral Metronomic Vinorelbine and PD-1 Inhibitors in Elderly Non-small Cell Lung Cancer
A clinical trial is investigating oral metronomic vinorelbine in combination with PD-1 inhibitors for elderly patients with non-small cell l…