Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2025-07-28Clinical Trial Update: Use of Chinese Herbal Formula Shu Yu Wan in Lung Cancer Patients [NA]
A clinical trial evaluating Shu Yu Wan, a Chinese herbal formula, for metastatic non-small cell lung cancer has been withdrawn.
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EMA approval · 2025-07-25EMA Authorised: Armisarte (previously Pemetrexed Actavis) (pemetrexed diacid monohydrate) — Actavis Group PTC ehf
Armisarte (pemetrexed diacid monohydrate) has been authorised in the EU for non-small cell lung cancer and mesothelioma; Actavis Group PTC e…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Phase Ib/II Study of Vebreltinib With Furmonertinib in NSCLC Patients With c-Met Amplification After EGFR-TKI Failure [Phase 1, Phase 2]
Phase Ib/II study evaluating the combination of vebreltinib with furmonertinib for non-small cell lung cancer with c-Met amplification after…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Tislelizumab Combined With sCRT in Stage IIIB/C-IV Non-Squamous Non-Small Cell Lung Cancer：A Prospective, Single-Arm, Phase II Study [Phase 2]
This document updates an ongoing, single-arm Phase II trial evaluating tislelizumab with sCRT (short-course chemoradiotherapy) in stage IIIB…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Electroacupuncture Combined With PD-1 Inhibitor for Elderly Patients With Advanced NSCLC [NA]
A clinical trial is evaluating electroacupuncture combined with a PD-1 inhibitor in elderly patients with advanced non-small cell lung cance…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: A Phase II Randomized Trial of Neoadjuvant Ivonescimab or Penpulimab Plus Chemotherapy in Resectable NSCLC [Phase 2]
A Phase II randomized trial is evaluating neoadjuvant Ivonescimab or Penpulimab plus chemotherapy in resectable non-small cell lung cancer, …
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Phase I/II Study of PLB1004 Combined With Platinum-based Doublet Chemotherapy in Patients With EGFR Mutation-positive [Phase 1, Phase 2]
Phase I/II trial evaluating PLB1004 in combination with platinum-based chemotherapy in EGFR mutation-positive non-small cell lung cancer; th…
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: Combination of Concurrent Chemoradiotherapy With Surufatinib and Tislelizumab in Patients With Locally Advanced Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial is evaluating the combination of concurrent chemoradiotherapy with surufatinib and tislelizumab for locally advance…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Perioperative Treatment of Sunvozertinib in Stage II-IIIB NSCLC [Phase 2]
Phase 2 trial evaluating perioperative treatment with sunvozertinib for stage II-IIIB non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Comprehensive Genomic Analysis in Tissue Samples From Patients With Recurrent or Stage IV Non-small Cell Lung Cancer [NA]
A clinical trial evaluating comprehensive genomic profiling in tissue samples from patients with recurrent or stage IV non-small cell lung c…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: A Study of Nivolumab and Ipilimumab in Untreated Participants With Stage 3 Non-small Cell Lung Cancer (NSCLC) That is Unable or Not Planned to be Removed by Surgery [Phase 3]
This document reports the completion of a Phase 3 study evaluating the combination of nivolumab and ipilimumab in untreated stage 3 non-smal…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: A Phase I Study of XZP-3621 in Chinese Patients With ALK or ROS1 Rearrangement Non-small Cell Lung Cancer [Phase 1]
A Phase I trial evaluating XZP-3621 in Chinese patients with ALK- or ROS1-rearranged non-small cell lung cancer has been completed.
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Pharmaco-economic Study of a Second Line Treatment in Advanced Non Small Cell Lung Cancer [Phase 3]
This document notes completion of a Phase 3 pharmaco-economic study evaluating a second-line treatment for advanced non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Trabedersen (OT-101) With Pembrolizumab for Newly Diagnosed Advanced NSCLC and Positive PD-L1 [Phase 1, Phase 2]
Phase 1/2 trial evaluating Trabedersen (OT-101) in combination with pembrolizumab for newly diagnosed advanced Non-small cell lung cancer wi…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Study of EGFR TKI in Patients With Advanced NSCLC Harbouring EGFR Mutations [Phase 2]
A Phase 2 clinical trial is investigating an EGFR tyrosine kinase inhibitor in patients with advanced non-small cell lung cancer carrying EG…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: A Study of CS1001 in Subjects With Stage IV Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 trial evaluating CS1001 in patients with stage IV non-small cell lung cancer is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Neoadjuvant Immunotherapy Plus Chemotherapy Followed by Concurrent Chemoradiotherapy and Consolidative Immunotherapy for Locally Advanced Non-small Cell Lung Cancer [Phase 3]
A Phase 3 trial evaluating neoadjuvant immunotherapy plus chemotherapy, followed by concurrent chemoradiotherapy and consolidative immunothe…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Copenhagen Master Observational Trial
A Copenhagen Master Observational Trial is currently recruiting. It studies patients with non-small cell lung cancer and breast cancer.
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Lorlatinib in ROS1+ NSCLC With Brain Metastasis [Phase 2]
Lorlatinib is being studied in a Phase 2 trial for ROS1-positive non-small cell lung cancer with brain metastases, which is currently not ye…
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: Study of DS-1062a Versus Docetaxel in Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer With or Without Actionable Genomic Alterations (TROPION-LUNG01) [Phase 3]
A Phase 3 trial comparing datopotamab deruxtecan (DS-1062a) to docetaxel in previously treated advanced or metastatic non-small cell lung ca…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Pembrolizumab and Chemotherapy Neoadjuvant/Adjuvant of NSCLC [Phase 2]
Phase 2 clinical trial evaluating pembrolizumab in combination with chemotherapy as neoadjuvant/adjuvant therapy for non-small cell lung can…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Hypofractionated Versus Conventional Chemoradiotherapy Followed by Consolidative Immunotherapy in Locally Advanced NSCLC [Phase 3]
A Phase 3 trial is evaluating hypofractionated chemoradiotherapy with consolidative immunotherapy versus conventional chemoradiotherapy for …
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: X-396(Ensartinib) Capsules in ALK-Positive NSCLC Patients With Brain Metastases [Phase 2]
Phase 2 study update of X-396 (ensartinib) in ALK-positive non-small cell lung cancer patients with brain metastases. The trial status is ac…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Expanded Access Protocol for the Use of SL-28 in the Treatment of Advanced Solid Tumors
This clinical trials update describes an expanded access protocol for SL-28 in patients with advanced solid tumors and lists eligible condit…
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: A Study of BL-B01D1 and Almonertinib in Patients With Resectable EGFR+ Stage II-IIIB NSCLC [Phase 2]
Phase 2 clinical trial evaluating BL-B01D1 in combination with Almonertinib for resectable EGFR-positive stage II-IIIB non-small cell lung c…