Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: Pemetrexed and Carboplatin With or Without Anlotinib Hydrochloride for Osimertinib-resistant Non-squamous NSCLC [Phase 2]
Phase 2 clinical trial at Fudan University evaluating pemetrexed and carboplatin with or without anlotinib for osimertinib-resistant non-squ…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Zusanli (ST36) Electroacupuncture Treatment for Neoadjuvant Immunotherapy in Non-Small Cell Lung Cancer [NA]
This clinical trial update reports on a study evaluating Zusanli (ST36) electroacupuncture in conjunction with neoadjuvant immunotherapy for…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Tracking T-Cell Responses to Evaluate Pembrolizumab Effectiveness in Advanced Non-Small Cell Lung Cancer [Phase 2]
This clinical trial update describes a Phase 2 study evaluating T-cell responses to pembrolizumab in advanced non-small cell lung cancer, cu…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Prophylactic Proton Pump Inhibition for Esophageal Protection in Lung Radiation Therapy [Phase 2]
A Phase 2 clinical trial protocol evaluating prophylactic proton pump inhibition to protect the esophagus during lung radiation therapy, cur…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Real-world Study of Taletrectinib for Advanced ROS1+ NSCLC With Brain Metastases
This entry describes a real-world study of Taletrectinib for advanced ROS1-positive non-small cell lung cancer with brain metastases, curren…
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: A Study in Patients With BRAF V600E-mutant Metastatic Non-small Cell Lung Cancer (OCTOPUS)
Clinical update on the OCTOPUS trial evaluating treatment for patients with BRAF V600E-mutant metastatic non-small cell lung cancer; the stu…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: ctDNA to Predict Response to Chemo-Immunotherapy and Detect Minimal Residual Disease in Non-Small Cell Lung Cancer [Phase 2]
This entry describes a Phase 2 trial evaluating whether circulating tumor DNA can predict response to chemo-immunotherapy and detect minimal…
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CLINICAL_TRIALS other · 2025-07-22Clinical Trial Update: Standard-of-care Systemic Therapy With or Without Local Therapy in Patients With Oligoprogressive Non-Small Cell Lung Cancer(NSCLC) [Phase 2, Phase 3]
This clinical trial update describes a Phase 2/Phase 3 study evaluating standard-of-care systemic therapy with or without local therapy for …
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: A Study on Exploring the Abscopal Effect Induced by Different Radioimmunotherapy Combination Patterns in the Treatment of Non-Small Cell Lung Cancer With Multiple Metastases [Phase 2]
Phase 2 clinical trial investigating whether different radioimmunotherapy combination patterns can elicit an abscopal effect in patients wit…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLC [Phase 1, Phase 2]
This entry announces an ongoing Phase Ib/II trial of M701 for malignant pleural effusions caused by non-small cell lung cancer (stage IV), c…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Using Urine Samples to Identify Lung Cancer
Memorial Sloan Kettering Cancer Center is conducting a trial evaluating urine-based methods to identify non-small cell lung cancer and is cu…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours [Phase 1, Phase 2]
NuCana plc announced termination of a Phase 1/2 trial evaluating NUC-3373 in combination with other agents for patients with advanced solid …
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Afatinib Combined With Chemotherapy as Conversion Therapy in Unresectable EGFR Sensitive Mutation-positive Stage III NSCLC [Phase 2]
Phase 2 clinical trial evaluating afatinib with chemotherapy as conversion therapy for unresectable EGFR-mutant Stage III non-small cell lun…
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: First Real-world Data on Unresectable Stage III NSCLC Patients Treated With Durvalumab After Chemoradiotherapy
This update presents the first real-world data on the use of durvalumab after chemoradiotherapy in patients with unresectable stage III non-…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: A Phase Ⅱ Study of RC108 in Combination With Furmonertinib for the First-line Treatment of EGFR-Mutated Combined MET-Positive Unresectable Locally Advanced or Recurrent Metastatic NSCLC [Phase 2]
A Phase II clinical trial is evaluating RC108 in combination with furmonertinib as first-line therapy for EGFR-mutated, MET-positive unresec…
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: Study of an Early Change of a Chemotherapeutic Doublet Versus Four Cycles of Chemotherapy in Advanced Non Small Cell Lung Cancer [Phase 2]
Phase 2 study evaluating early switch of a chemotherapy doublet versus four cycles of chemotherapy in advanced non-small cell lung cancer ha…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Analysis of Circulating Tumor DNA Dynamics to Predict and Monitor Response to TKI in Patients With Advanced NSCLC.
This clinical trial registry entry describes a study evaluating circulating tumor DNA dynamics to predict and monitor response to tyrosine k…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: Tislelizumab Combined With Recombinant Human Endostatin Combined With Chemotherapy for Unresectable Stage III Non-small Cell Lung Cancer. [Phase 2]
Phase 2 trial evaluating tislelizumab with recombinant human endostatin and chemotherapy for unresectable stage III non-small cell lung canc…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products
This clinical trial update reports long-term follow-up of participants treated with A2 Biotherapeutics' gene therapy products in solid tumor…
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: ELVN-002 in HER2 Mutant Non-Small Cell Lung Cancer [Phase 1]
Phase 1 trial ELVN-002 for HER2-mutant non-small cell lung cancer and HER2-positive metastatic breast cancer is active but not recruiting.
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: Astra Zeneca (Immuno Stereotactic Ablative Body Radiotherapy) ISABR Study: Randomized Phase I/II Study of Stereotactic Body Radiotherapy [Phase 1, Phase 2]
The ISABR trial is a randomized Phase I/II study evaluating immuno stereotactic ablative body radiotherapy for non-small cell lung cancer. T…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies [Phase 1, Phase 2]
SPEDOX-6, a single protein encapsulated doxorubicin, is being studied in Phase 1/2 trials for several advanced cancers and is currently recr…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Omitting Clinical Target Volume in Radical Treatment of Unresectable Stage III Non-small Cell Lung Cancer
Clinical trial update evaluating omission of the clinical target volume in radical treatment for unresectable stage III non-small cell lung …
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Efficacy and Safety of Super-hyperfractionation Pulse Radiotherapy Combined With ICIs for Advanced NSCLC [NA]
Clinical trial update describing a study of super-hyperfractionation pulse radiotherapy combined with immune checkpoint inhibitors for advan…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Study on the Optimal Combination Pattern of the Combined Treatment of Radiotherapy and Immunotherapy for the Abscopal Effect in Non-Small Cell Lung Cancer (NSCLC) With Multiple Metastases [Phase 2]
A Phase 2 clinical trial evaluating the optimal combination of radiotherapy and immunotherapy to induce the abscopal effect in patients with…