Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: CT-95 in Advanced Cancers Associated With Mesothelin Expression [Phase 1]
Phase 1 trial CT-95 for mesothelin-expressing tumors is currently recruiting across multiple indications, including epithelial ovarian cance…
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: MGC018 With or Without MGA012 in Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update reports results from the combination of MGC018 with or without MGA012 (pembrolizumab) in advanced solid tumors. T…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: SDTM001 Injection as Adjuvant Therapy for NSCLC Patients After Radical Surgical Resection [Phase 1]
Phase 1 clinical trial update for SDTM001 Injection as adjuvant therapy in patients with Non-Small Cell Lung Cancer after radical surgical r…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: EMPATHY NSCLC: European Registry for Plasma-Based Molecular Profiling in Advanced NSCLC Patients
This document describes the EMPATHY NSCLC study, a European registry for plasma-based molecular profiling in patients with advanced non-smal…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRs
Alaunos Therapeutics reports long-term follow-up data from subjects treated with autologous T cells engineered with a Sleeping Beauty system…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Camu-Camu Prebiotic and Immune Checkpoint Inhibition in Patients With Non-small Cell Lung Cancer and Melanoma [Phase 1]
Phase 1 trial evaluating Camu-Camu prebiotic with immune checkpoint inhibition in patients with advanced non-small cell lung cancer and mela…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Role of Cancer-associated Fibroblast, MDSCs and Immune Cell Interplays in the Resistance of Non-small Cell Lung Cancer to Anti-PD1/PD-L1 Therapies
This clinical trial examines how cancer-associated fibroblasts, myeloid-derived suppressor cells, and immune cell interactions contribute to…
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CLINICAL_TRIALS withdrawal · 2025-07-30Clinical Trial Update: HLA Typing & Tumor Neoantigen Identification for Phase I/II Study of Autologous TCR-T Cells in Subjects With Solid Tumors
Alaunos Therapeutics reports termination of a Phase I/II autologous TCR-T cell trial across several solid tumors. The study focused on HLA t…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: A Real-world Study of Adjuvant Therapy in Early Stage NSCLC With EGFR Mutation-Positive in China
This clinical trial update reports a completed real-world study in China examining adjuvant therapy for early-stage non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Study of GT103 in Combination With Pembrolizumab in Refractory, Metastatic Non-Small Cell Lung Cancer [Phase 2]
Phase 2 study of GT103 in combination with pembrolizumab for refractory, metastatic non-small cell lung cancer has been terminated.
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Consolidation Radiotherapy vs. Observation in Oligoresidual Advanced Non-Small Cell Lung Cancer After Chemo-Immunotherapy [Phase 2]
Phase 2 clinical trial comparing consolidation radiotherapy versus observation in oligoresidual advanced non-small cell lung cancer after ch…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor [Phase 1, Phase 2]
Update on a Phase I/II autologous engineered TCR T-cell therapy trial for advanced pancreatic ductal adenocarcinoma, non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Efficacy and Safety Analysis of First-Line ABCP Therapy in Advanced SMARCA4-Mutated NSCLC
The update outlines an ongoing trial evaluating first-line ABCP therapy for advanced SMARCA4-mutated non-small cell lung cancer, with the st…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: A Study to Evaluate Pembrolizumab Plus Lenvatinib in PD-L1 Positive TKI Resistant NSCLC Patients [Phase 2]
This update describes a Phase 2 trial evaluating the combination of pembrolizumab and lenvatinib in PD-L1 positive, TKI-resistant non-small …
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Follow-up of Patients With Curative-intent Surgical Resection for NSCLC [NA]
A completed clinical trial evaluating outcomes after curative-intent surgical resection for non-small cell lung cancer.
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Role of MDSCs and Cancer Stem Cells and Their Cross Talks in NSCLC
A clinical trial update describes investigation into the roles of myeloid-derived suppressor cells and cancer stem cells and their interacti…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Effect of G-CSF on MDSC and Cancer Stem-cells Interactions in Non-small Cell Lung Cancers (CIRCUIT) [NA]
Clinical trial CIRCUIT investigates how granulocyte colony-stimulating factor affects interactions between MDSCs and cancer stem cells in no…
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: Immunotherapy With Non-Ablative Radiation in Previously Untreated Patients With Stage IV NSCLC [Phase 2]
A Phase 2 trial of immunotherapy combined with non-ablative radiation in previously untreated stage IV non-small cell lung cancer was termin…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Trial for Local Ablative Treatment (LAT) Optimization in Patients With Advanced Non-Small Cells Lung Cancer (NSCLC) Presenting an Anaplastic Lymphoma Kinase (ALK) Rearrangement Treated by Brigatinib [Phase 2]
Phase 2 trial assessing local ablative treatment optimization in advanced ALK-rearranged non-small cell lung cancer patients treated with br…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Firmonertinib Combined With Intrathecal Injection for the Treatment of EGFR Mutant NSCLC With Leptomeningeal Metastases [Phase 4]
A Phase 4 trial evaluating firmonertinib in combination with intrathecal injection for EGFR-mutant non-small cell lung cancer with leptomeni…
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CLINICAL_TRIALS trial_result · 2025-07-28Clinical Trial Update: A Study of Subcutaneous (SC) Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) vs Intravenous Pembrolizumab in Adult Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) (MK-3475A-D77) [Phase 3]
Phase 3 trial comparing subcutaneous pembrolizumab coformulated with hyaluronidase alfa (MK-3475A) vs intravenous pembrolizumab in adults wi…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Tislelizumab Combined With Anlotinib and Nab-paclitaxel in III Resectable Non-small Cell Lung Cancer(TitAN) : A Prospective, Single-Arm, Phase II Study [Phase 2]
A prospective Phase II, single-arm trial evaluating tislelizumab in combination with anlotinib and nab-paclitaxel in III resectable non-smal…
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CLINICAL_TRIALS trial_result · 2025-07-28Clinical Trial Update: VARGADO - Vargatef in 2nd-line Therapy of Non-Small Cell Lung Cancer (NSCLC)
The Boehringer Ingelheim-sponsored trial evaluating Vargatef as second-line therapy for non-small cell lung cancer has completed.
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Anti-CD38 Antibody With KRAS Vaccine and Anti-PD-1 Antibody in Subjects With Pancreatic Ductal Adenocarcinoma and Refractory Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial tests an anti-CD38 antibody with a KRAS vaccine and an anti-PD-1 antibody in pancreatic ductal adenocarcinoma and r…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Ruxolitinib for Cancer Cachexia [EARLY_Phase 1]
An early-phase 1 clinical trial is evaluating ruxolitinib for cancer cachexia in patients with stage IV non-small cell lung cancer, and the …