Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: A Single-center, Phase II Clinical Trial Evaluating the Efficacy of Sacituzumab Tirumotecan in Combination With Tagitanlimab as Neoadjuvant Therapy for PD-L1-positive, Resectable Stage II to IIIB Non-small Cell Lung Cancer (NSCLC) [Phase 2]
A Phase II, single-center trial is evaluating the combination of sacituzumab tirumotecan with tagitanlimab as neoadjuvant therapy for PD-L1-…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: A Clinical Study of BT02 in Treating Patients With Advanced Lung Cancer [Phase 1]
A Phase 1 clinical trial update for BT02 in advanced lung cancer, including Non-Small Cell Lung Cancer and Small Cell Lung Cancer, with stat…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: AI-Based DeepGEM Tool for Predicting Gene Mutations in NSCLC Patients: A Randomized Controlled Study [NA]
A randomized controlled study evaluating an AI-based DeepGEM tool to predict gene mutations in Non-small cell lung cancer patients; the tria…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Toripalimab Combined With Chemotherapy as Adjuvant Therapy for Non-small Cell Lung Cancer With or Without Prior Neoadjuvant Therapy [Phase 2]
A Phase 2 clinical trial evaluating toripalimab in combination with chemotherapy as adjuvant therapy for stage IB-IIIB non-small cell lung c…
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FDA approval · 2025-08-06FDA Approved: PEMETREXED — Supplemental Application (Accord Healthcare Inc.)
FDA approved a supplemental application for pemetrexed by Accord Healthcare Inc., enabling the generic version to be marketed under approved…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: A Clinical Study to Evaluate the Efficacy and Safety of HLX26 (Anti-LAG-3 Monoclonal Antibody Injection) Combined With Serplulimab and Chemotherapy in Previously Untreated Advanced NSCLC Patients [Phase 2]
Phase 2 clinical study evaluating HLX26 in combination with Serplulimab and chemotherapy in previously untreated advanced non-small cell lun…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: AI Models for Predicting Occult Pleural Dissemination in NSCLC
Clinical trial investigating AI models to predict occult pleural dissemination in non-small cell lung cancer has completed. The study was sp…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Multimodal Large Model-Driven Risk and Prognosis Assessment for Brain Metastases in Lung Cancer
This document reports a clinical trial investigating AI-driven risk and prognosis assessment for brain metastases in non-small cell lung can…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Analysis of Biological Characteristics of Advanced ALK-rearranged NSCLC [NA]
This study analyzes the biological characteristics of advanced ALK-rearranged non-small cell lung cancer. It is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-04Clinical Trial Update: Observational Prospective Study of Quality of Life in Unresectable TNM Stage III NSCLC (OBSTINATE)
An observational prospective study (OBSTINATE) evaluating quality of life in patients with unresectable TNM stage III non-small cell lung ca…
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CLINICAL_TRIALS research · 2025-08-04Clinical Trial Update: Mechanisms of Resistance to Amivantamab in Patients With NSCLC With EGFR Exon 20 Insertion [NA]
An update on a clinical trial investigating how resistance to amivantamab may develop in non-small cell lung cancer patients with EGFR exon …
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EMA approval · 2025-08-04EMA Authorised: Docetaxel Kabi (docetaxel) — Fresenius Kabi Deutschland GmbH
The EMA authorised Docetaxel Kabi (docetaxel) from Fresenius Kabi Deutschland GmbH for multiple cancer indications, including head and neck …
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: A Study of BL-M07D1 in Patients With HER2-mutated, Locally Advanced or Metastatic Non-small-cell Lung Cancer [Phase 1, Phase 2]
This update describes an ongoing Phase 1/2 study of BL-M07D1 in patients with HER2-mutated, locally advanced or metastatic non-small-cell lu…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Study of Inupadenant (EOS100850) With Chemotherapy as Second Line Treatment for Nonsquamous Non-small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating Inupadenant (EOS100850) with chemotherapy as second-line treatment for nonsquamous non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: A Study of Real-world Treatment Patterns and Outcomes in Chinese Advanced NSCLC Patients Who Previously Received at Least 2 Line Treatments
This clinical trial update reports on real-world treatment patterns and outcomes in Chinese patients with advanced non-small cell lung cance…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: To Evaluate OBI-833/OBI-821 in Combination With First-Line Erlotinib in Patients With EGFR-Mutated, Globo H-Positive, Locally Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating the combination of OBI-833/OBI-821 with first-line erlotinib in EGFR-mutant, Globo H-positive locally adva…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Taxoprexin Plus Carboplatin Treatment for Advanced Lung Cancer [Phase 3]
A Phase 3 trial evaluating Taxoprexin with carboplatin for advanced non-small cell lung cancer has completed. Results have been posted.
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: SBRT With Immunotherapy in Early Stage Non-small Cell Lung Cancer: Tolerability and Lung Effects [Phase 1, Phase 2]
Phase 1/2 clinical trial assessing SBRT with immunotherapy for early-stage non-small cell lung cancer, focusing on tolerability and lung eff…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Prognostic Value of Sarcopenia and Nutritional Status in Early-stage Non-small Cell Lung Cancer
A completed study investigated whether sarcopenia and nutritional status can prognosticate outcomes in patients with early-stage non-small c…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: The Lung Health Check Pilot [NA]
Clinical trial update for the Lung Health Check Pilot; the study on non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Subcostal Single-port Versus Intercostal Multi-port Robotic Lobectomy for Non-small Cell Lung Cancer
A completed clinical trial comparing subcostal single-port robotic lobectomy versus intercostal multi-port robotic lobectomy for non-small c…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Study of Pembrolizumab/Vibostolimab (MK-7684A) in Combination With Concurrent Chemoradiotherapy Followed by Pembrolizumab/Vibostolimab Versus Concurrent Chemoradiotherapy Followed by Durvalumab in Participants With Stage III Non-small Cell Lung Cancer (MK-7684A-006) [Phase 3]
Phase 3 study MK-7684A-006 is evaluating pembrolizumab/vibostolimab with concurrent chemoradiotherapy, followed by maintenance pembrolizumab…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Perioperative Study of Iparomlimab and Tuvonralimab in Resectable NSCLC [Phase 2]
Phase 2 perioperative trial evaluating iparomlimab and tuvonralimab in resectable non-small cell lung cancer, currently recruiting.
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: A Study of HS-20117 Combined With Aumolertinib in Participants With Advanced Non-Squamous Non-Small Cell Lung Cancer [Phase 2, Phase 3]
A study of HS-20117 in combination with Aumolertinib is being conducted for advanced non-squamous non-small cell lung cancer in Phase 2/3, a…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction SBRT for Metastasis-directed Treatment (SPRINT) [NA]
This TWiCs trial compares acute toxicity of single-fraction versus multiple-fraction SBRT for metastasis-directed treatment across several c…