Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: PH009-1 in Patients With EGFR Mutation Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) [Phase 1, Phase 2]
PH009-1 is an investigational therapy for EGFR-mutated non-small cell lung cancer (locally advanced or metastatic), and the Phase 1/2 trial …
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Bronchoscopic Cryoablation Combined With Chemo-Immunotherapy in NSCLC With Central Airway Obstruction [Phase 2]
This is an ongoing Phase 2 clinical trial investigating bronchoscopic cryoablation combined with chemotherapy and immunotherapy in patients …
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Harnessing Allo-immunity to Enhance Immune Checkpoint Inhibitor Responses in Advanced NSCLC [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial investigating allo-immunity to boost immune checkpoint inhibitor responses in Stage IV non-small cell lung …
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: The Patient-Reported Outcomes in ALK Positive Advanced NSCLC in China
This clinical trial update reports a study in China evaluating patient-reported outcomes in ALK-positive advanced non-small cell lung cancer…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Phase 1b/2 Study of Futibatinib in Combination With Binimetinib in Patients With Advanced KRAS Mutant Cancer [Phase 1]
The trial update indicates termination of the Phase 1b/2 study of futibatinib in combination with binimetinib for advanced KRAS-mutant cance…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: PD-1 Combined With Pyrotinib for Chemotherapy Failure HER2 Insertion Mutation Advanced NSCLC [Phase 2]
Phase 2 trial evaluating a PD-1 inhibitor in combination with Pyrotinib for chemotherapy-refractory non-small cell lung cancer with HER2 ins…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Sunvozertinib Plus Anlotinib as 1L Treatment in EGFR-Sensitive Mutations Combined With Co-Mutations Advanced NSCLC [Phase 2]
A Phase 2 trial evaluating Sunvozertinib plus Anlotinib as first-line therapy for EGFR-sensitizing mutations with co-mutations in advanced n…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: High-dose Furmonertinib for First-line Treatment of EGFR Mutated NSCLC With Central Nervous System (CNS) Metastases [Phase 2]
This update describes a Phase 2 trial evaluating high-dose furmonertinib as first-line treatment for EGFR-mutated non-small cell lung cancer…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Real-World Study of Treatment Patterns and Effectiveness in MET Mutation-Positive Advanced Lung Cancer
A real-world study protocol evaluating treatment patterns and effectiveness in MET mutation-positive advanced lung cancer, currently recruit…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Ensartinib in Combination With Bevacizumab in ALK-positive NSCLC Patients With TP53 Mutation [Phase 2]
Phase 2 trial evaluating ensartinib in combination with bevacizumab in ALK-positive non-small cell lung cancer patients with TP53 mutation i…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Phase II Clinical Trial to Evaluate the Safety and Efficacy of TQB2450 Injection Combined With Anlotinib Capsule and Chemotherapy in the Treatment of Immunoresistant Advanced Non-small Cell Lung Cancer [Phase 2]
Phase II clinical trial evaluating TQB2450 in combination with Anlotinib capsule and chemotherapy for immunoresistant advanced non-small cel…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Phase Ib Study of HS-10370 in Addition to Other Anti-cancer Therapies in Participants with KRAS G12C Mutation Advanced Solid Tumors [Phase 1]
A Phase Ib trial evaluating HS-10370 in combination with other anti-cancer therapies for KRAS G12C-mutant advanced solid tumors, including n…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Induction Therapy With Serplulimab Combined With Chemotherapy for Unresectable Stage III Non-small Cell Lung Cancer
This document reports a clinical trial evaluating induction therapy with Serplulimab plus chemotherapy for unresectable stage III non-small …
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Chemotherapy Combined With Immunotherapy in HER 2 Insertion or Amplification Advanced NSCLC
A clinical trial update indicates a study evaluating chemotherapy combined with immunotherapy for HER2 insertion or amplification in advance…
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Using Circulating Tumor DNA to Personalize Duration of Consolidation Durvalumab [Phase 2]
A Phase 2 trial evaluating personalized duration of consolidation durvalumab guided by circulating tumor DNA in stage III non-small cell lun…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Improving the Intraoperative Diagnosis Accuracy of Invasiveness for Small-sized Lung Adenocarcinoma
A clinical trial update indicates a recruiting study at Union Hospital, Tongji Medical College, Huazhong University of Science and Technolog…
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CLINICAL_TRIALS other · 2024-09-19Clinical Trial Update: Pembrolizumab Combined With Double Platinum Based Chemotherapy for Potentially Resectable NSCLC
A clinical trial evaluating pembrolizumab in combination with double platinum-based chemotherapy for potentially resectable non-small cell l…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Atezolizumab Combined With Platinum-based Chemotherapy as Neoadjuvant Therapy for Patients With Resectable Stage II-IIIB [Phase 2]
A Phase 2 trial evaluating atezolizumab plus platinum-based chemotherapy as neoadjuvant therapy for resectable stage II-IIIB non-small cell …
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CLINICAL_TRIALS other · 2024-09-19Clinical Trial Update: Induction Therapy With PD-1 Antibody Combined With Platinum-based Doublet Chemotherapy for Locally-advanced Non-small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating induction therapy with a PD-1 antibody in combination with platinum-based doublet chemotherapy for local…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: The Effects of an Nutritional Intervention on PD-1 ICI in NSCLC [NA]
A completed clinical trial evaluating the effects of a nutritional intervention on PD-1 immune checkpoint inhibitor therapy in non-small cel…
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: CARE Initiative: Real-world Emulation of the KEYNOTE-189 Trial [DS4]
Aetion's CARE Initiative reports completion of a real-world emulation study based on the KEYNOTE-189 trial in metastatic non-small cell lung…
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CLINICAL_TRIALS research · 2024-09-05Clinical Trial Update: A Clinical Trial of Furmonertinib Combination Therapy As Neoadjuvant Treatment in Resectable EGFR-Mutated NSCLC [Phase 2]
A Phase 2 clinical trial is evaluating furmonertinib in combination as neoadjuvant therapy for resectable EGFR-mutated non-small cell lung c…
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: Clinical Trial of TQB2928 in Combination With a Third-Generation Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI) in Patients With Advanced Non-Small Cell Lung Cancers [Phase 1]
A Phase 1 trial is evaluating TQB2928 in combination with a third-generation EGFR tyrosine kinase inhibitor for advanced non-small cell lung…
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: Icotinib Following Chemotherapy Versus Chemotherapy as Adjuvant Therapy in Stage IIA-IIIA NSCLC With EGFR Mutation [Phase 3]
Phase 3 trial comparing icotinib after chemotherapy versus chemotherapy alone as adjuvant therapy in stage IIA-IIIA non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: ctDNA Dynamic Monitoring and Its Role of Prognosis in Stage I NSCLS by NGS
This clinical trial update reports on using dynamic monitoring of circulating tumor DNA (ctDNA) by next-generation sequencing to assess prog…