Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-09-25Clinical Trial Update: Association Between Microbiome and the Efficacy and Safety of PD-1/PD-L1 Blockade in Resectable NSCLC
A clinical trial investigating whether the gut microbiome influences the efficacy and safety of PD-1/PD-L1 blockade in patients with resecta…
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CLINICAL_TRIALS research · 2024-09-25Clinical Trial Update: Lifei Xiaoji Wan in Treatment of Advanced NSCLC [NA]
Clinical trial update for Lifei Xiaoji Wan in treating advanced non-small cell lung cancer; recruiting.
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FDA approval · 2024-09-24FDA Approved: GEMCITABINE HYDROCHLORIDE — Supplemental Application (Teyro Labs Private Limited)
FDA approved a supplemental application for Gemcitabine hydrochloride from Teyro Labs Private Limited, authorizing continued approval of thi…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: A Study Comparing Savolitinib Plus Osimertinib vs Savolitinib Plus Placebo in Patients With EGFRm+ and MET Amplified Advanced NSCLC [Phase 2]
This Phase 2 trial in EGFR-mutant, MET-amplified advanced non-small cell lung cancer compares Savolitinib plus Osimertinib versus Savolitini…
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: CARE Initiative: Real-world Emulation of the KEYNOTE-189 Trial [DS3]
A real-world emulation study by Aetion evaluating the KEYNOTE-189 regimen in metastatic non-small cell lung cancer. The study status is COMP…
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CLINICAL_TRIALS research · 2024-09-23Clinical Trial Update: MONDRIAN: Multi-omics Integrative Modelling for Stereotactic Body Radiotherapy in Early-stage Non-small Cell Lung Cancer
MONDRIAN is a clinical trial investigating a multi-omics integrative modelling approach to guide stereotactic body radiotherapy in early-sta…
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CLINICAL_TRIALS research · 2024-09-23Clinical Trial Update: Sequential Chemo-immunotherapy Plus Thoracic Radiotherapy for Elderly And/or Frail Stage III Non-small-cell Lung Cancer [NA]
A clinical trial evaluating sequential chemo-immunotherapy followed by thoracic radiotherapy for elderly and/or frail patients with stage II…
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CLINICAL_TRIALS research · 2024-09-23Clinical Trial Update: Neoadjuvant With Tα1 Plus Immuno-chemotherapy for Resectable NSCLC [NA]
This clinical trial update describes a neoadjuvant study combining thymosin alpha-1 with immuno-chemotherapy for resectable non-small cell l…
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CLINICAL_TRIALS research · 2024-09-20Clinical Trial Update: Intrathecal Pemetrexed Combined With High-dose Furmonertinib and Beva for EGFR-m NSCLC With Leptomeningeal Metastases [Phase 2]
A Phase 2 trial update describing a novel combination of intrathecal pemetrexed with high-dose furmonertinib and bevacizumab for EGFR-mutant…
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CLINICAL_TRIALS research · 2024-09-20Clinical Trial Update: ALK Tyrosine Kinase Inhibitors in ALK-rearranged Advanced Squamous Cell Carcinoma [Phase 2]
This clinical trial is evaluating ALK tyrosine kinase inhibitors in ALK-rearranged advanced squamous cell carcinoma (a form of non-small cel…
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CLINICAL_TRIALS research · 2024-09-20Clinical Trial Update: Sunvozertinib Plus Anlotinib as 1L Treatment in EGFR Mutant Advanced NSCLC-RW [Phase 2]
A Phase 2 clinical trial is investigating Sunvozertinib in combination with Anlotinib as first-line treatment for EGFR-mutant advanced non-s…
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CLINICAL_TRIALS research · 2024-09-20Clinical Trial Update: A Study With Central Nervous System Metastatic EGFR Mutation Positive Non-small Cell Lung Cancer
A clinical trial update describing a study of EGFR mutation-positive non-small cell lung cancer with central nervous system metastases. The …
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CLINICAL_TRIALS withdrawal · 2024-09-20Clinical Trial Update: Immunogenicity and Safety of Pneumococcal Vaccination in Patients Treated With Immune Checkpoint Inhibitors
The clinical trial evaluating immunogenicity and safety of pneumococcal vaccination in patients treated with immune checkpoint inhibitors fo…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Efficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage II, IIIA, and Resectable IIIB (T3-4N2) Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671) [Phase 3]
Phase 3 MK-3475-671 evaluates pembrolizumab added to platinum-doublet chemotherapy as neoadjuvant/adjuvant therapy for resectable stage II, …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Efficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage II, IIIA, and Resectable IIIB (T3-4N2) Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671) [Phase 3]
Phase 3 trial evaluating pembrolizumab with platinum doublet chemotherapy as neoadjuvant/adjuvant therapy for resectable stage II-IIIA and s…
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FDA approval · 2024-09-19FDA Approved: RYBREVANT — Supplemental Application (Janssen Biotech, Inc.)
The FDA approved a supplemental application for RYBREVANT (amivantamab-vmjw) from Janssen Biotech, Inc.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Molecular Profiling Study of Patients With EGFR Mutation-positive Locally Advanced or Metastatic NSCLC Treated With Osimertinib [Phase 2]
Phase 2 molecular profiling study of patients with EGFR mutation-positive locally advanced or metastatic non-small cell lung cancer treated …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: SinTilimab After Radiation (STAR Study) [Phase 2]
Phase 2 STAR trial evaluating SinTilimab after radiation for non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Trial Evaluating Stereotactic Radiotherapy Plus Durvalumab Continuation for Patients With NSCLC Metachronous Oligometastatic Disease Under Durvalumab Consolidation Following Chemoradiation [Phase 2]
A Phase 2 clinical trial evaluating continuation of durvalumab with added stereotactic radiotherapy for non-small cell lung cancer patients …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: JAB-3068 Activity in Adult Patients With Advanced Solid Tumors [Phase 1, Phase 2]
A completed Phase 1/Phase 2 trial update for JAB-3068 in adults with advanced solid tumors, including Esophageal Squamous Cell Carcinoma, No…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Radiotherapy to the Primary in Metastatic Non-small Cell Lung Cancer Patients [Phase 3]
A Phase 3 trial evaluating radiotherapy to the primary tumor in metastatic non-small cell lung cancer has completed.
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Immuno-effect of Tα1 for Stage I NSCLC [NA]
A clinical trial update noting ongoing recruitment for a study examining the immune effects of thymosin alpha-1 in Stage I non-small cell lu…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Retrospective Study: Evaluation of the Efficacy of Immunotherapy With Rare Mutations in Non-small Cell Lung Cancer
This document describes a retrospective study evaluating the efficacy of immunotherapy in non-small cell lung cancer patients with rare muta…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Anaplastic Lymphoma Kinase (ALK)-Positive Non-small Cell Lung Cancer (NSCLC) Post-alectinib Treatment Patterns
Pfizer's completed trial evaluates post-alectinib treatment patterns in ALK-positive non-small cell lung cancer. The study results have been…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Reinforced and Non-Reinforced Staple Lines in Fissureless Lobectomy [Phase 1]
A Phase 1 clinical trial evaluating reinforced versus non-reinforced staple lines in fissureless lobectomy for lung cancer, currently not re…